Export your current network:
... as a bitmap image:
file format is 'PNG': portable network graphic
... as a high-resolution bitmap:
same PNG format, but resolution at 400 dpi
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as simple tabular text output:
TSV: tab separated values - can be opened in Excel
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and annotated functions of the network proteins
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ACTB | PFN3 | ENSP00000349960 | ENSP00000351379 | actin, beta | profilin 3; Binds to actin and affects the structure of the cytoskeleton (By similarity). May be involved in spermatogenesis | 0.814 |
| ACTB | VCL | ENSP00000349960 | ENSP00000211998 | actin, beta | vinculin; Actin filament (F-actin)-binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell- surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion | 0.872 |
| ACTRT3 | DIAPH2 | ENSP00000333037 | ENSP00000321348 | actin-related protein T3 | diaphanous homolog 2 (Drosophila); Could be involved in oogenesis. Involved in the regulation of endosome dynamics. Implicated in a novel signal transduction pathway, in which isoform 3 and CSK are sequentially activated by RHOD to regulate the motility of early endosomes through interactions with the actin cytoskeleton | 0.482 |
| ACTRT3 | PFN3 | ENSP00000333037 | ENSP00000351379 | actin-related protein T3 | profilin 3; Binds to actin and affects the structure of the cytoskeleton (By similarity). May be involved in spermatogenesis | 0.543 |
| APBB1IP | PFN3 | ENSP00000365411 | ENSP00000351379 | amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein; Appears to function in the signal transduction from Ras activation to actin cytoskeletal remodeling. Suppresses insulin- induced promoter activities through AP1 and SRE. Mediates Rap1- induced adhesion | profilin 3; Binds to actin and affects the structure of the cytoskeleton (By similarity). May be involved in spermatogenesis | 0.800 |
| DIAPH1 | PFN3 | ENSP00000381565 | ENSP00000351379 | diaphanous homolog 1 (Drosophila); Acts in a Rho-dependent manner to recruit PFY1 to the membrane. Required for the assembly of F-actin structures, such as actin cables and stress fibers. Nucleates actin filaments. Binds to the barbed end of the actin filament and slows down actin polymerization and depolymerization. Required for cytokinesis, and transcriptional activation of the serum response factor. DFR proteins couple Rho and Src tyrosine kinase during signaling and the regulation of actin dynamics. Functions as a scaffold protein for MAPRE1 and APC to stabilize microtubules and pr [...] | profilin 3; Binds to actin and affects the structure of the cytoskeleton (By similarity). May be involved in spermatogenesis | 0.806 |
| DIAPH2 | ACTRT3 | ENSP00000321348 | ENSP00000333037 | diaphanous homolog 2 (Drosophila); Could be involved in oogenesis. Involved in the regulation of endosome dynamics. Implicated in a novel signal transduction pathway, in which isoform 3 and CSK are sequentially activated by RHOD to regulate the motility of early endosomes through interactions with the actin cytoskeleton | actin-related protein T3 | 0.482 |
| DIAPH2 | PFN3 | ENSP00000321348 | ENSP00000351379 | diaphanous homolog 2 (Drosophila); Could be involved in oogenesis. Involved in the regulation of endosome dynamics. Implicated in a novel signal transduction pathway, in which isoform 3 and CSK are sequentially activated by RHOD to regulate the motility of early endosomes through interactions with the actin cytoskeleton | profilin 3; Binds to actin and affects the structure of the cytoskeleton (By similarity). May be involved in spermatogenesis | 0.806 |
| PFN3 | ACTB | ENSP00000351379 | ENSP00000349960 | profilin 3; Binds to actin and affects the structure of the cytoskeleton (By similarity). May be involved in spermatogenesis | actin, beta | 0.814 |
| PFN3 | ACTRT3 | ENSP00000351379 | ENSP00000333037 | profilin 3; Binds to actin and affects the structure of the cytoskeleton (By similarity). May be involved in spermatogenesis | actin-related protein T3 | 0.543 |
| PFN3 | APBB1IP | ENSP00000351379 | ENSP00000365411 | profilin 3; Binds to actin and affects the structure of the cytoskeleton (By similarity). May be involved in spermatogenesis | amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein; Appears to function in the signal transduction from Ras activation to actin cytoskeletal remodeling. Suppresses insulin- induced promoter activities through AP1 and SRE. Mediates Rap1- induced adhesion | 0.800 |
| PFN3 | DIAPH1 | ENSP00000351379 | ENSP00000381565 | profilin 3; Binds to actin and affects the structure of the cytoskeleton (By similarity). May be involved in spermatogenesis | diaphanous homolog 1 (Drosophila); Acts in a Rho-dependent manner to recruit PFY1 to the membrane. Required for the assembly of F-actin structures, such as actin cables and stress fibers. Nucleates actin filaments. Binds to the barbed end of the actin filament and slows down actin polymerization and depolymerization. Required for cytokinesis, and transcriptional activation of the serum response factor. DFR proteins couple Rho and Src tyrosine kinase during signaling and the regulation of actin dynamics. Functions as a scaffold protein for MAPRE1 and APC to stabilize microtubules and pr [...] | 0.806 |
| PFN3 | DIAPH2 | ENSP00000351379 | ENSP00000321348 | profilin 3; Binds to actin and affects the structure of the cytoskeleton (By similarity). May be involved in spermatogenesis | diaphanous homolog 2 (Drosophila); Could be involved in oogenesis. Involved in the regulation of endosome dynamics. Implicated in a novel signal transduction pathway, in which isoform 3 and CSK are sequentially activated by RHOD to regulate the motility of early endosomes through interactions with the actin cytoskeleton | 0.806 |
| PFN3 | VCL | ENSP00000351379 | ENSP00000211998 | profilin 3; Binds to actin and affects the structure of the cytoskeleton (By similarity). May be involved in spermatogenesis | vinculin; Actin filament (F-actin)-binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell- surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion | 0.800 |
| VCL | ACTB | ENSP00000211998 | ENSP00000349960 | vinculin; Actin filament (F-actin)-binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell- surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion | actin, beta | 0.872 |
| VCL | PFN3 | ENSP00000211998 | ENSP00000351379 | vinculin; Actin filament (F-actin)-binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell- surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion | profilin 3; Binds to actin and affects the structure of the cytoskeleton (By similarity). May be involved in spermatogenesis | 0.800 |
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