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PVALB | parvalbumin; In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions (110 aa) | |||
CD38 | CD38 molecule; Synthesizes cyclic ADP-ribose, a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system (300 aa) | |||
OCM | oncomodulin; Has some calmodulin-like activity with respect to enzyme activation and growth regulation. Binds two calcium ions (109 aa) | |||
UNG | uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity) (313 aa) | |||
OCM2 | oncomodulin 2 (109 aa) | |||
EFCAB6 | EF-hand calcium binding domain 6 (1501 aa) | |||
CALB1 | calbindin 1, 28kDa; Buffers cytosolic calcium. May stimulate a membrane Ca(2+)-ATPase and a 3’,5’-cyclic nucleotide phosphodiesterase (261 aa) | |||
RHBDL3 | rhomboid, veinlet-like 3 (Drosophila); May be involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors (By similarity) (404 aa) | |||
CALM2 | calmodulin 2 (phosphorylase kinase, delta) (149 aa) | |||
CALM3 | calmodulin 3 (phosphorylase kinase, delta) (149 aa) | |||
CABP5 | calcium binding protein 5; Inhibits calcium-dependent inactivation of L-type calcium channel and shifts voltage dependence of activation to more depolarized membrane potentials. Involved in the transmission of light signals (By similarity) (173 aa) | |||
CABP2 | calcium binding protein 2 (220 aa) | |||
CALB2 | calbindin 2; Calretinin is a calcium-binding protein which is abundant in auditory neurons (271 aa) | |||
CABP1 | calcium binding protein 1; Modulates calcium-dependent activity of inositol 1,4,5- triphosphate receptors (ITPRs). Inhibits agonist-induced intracellular calcium signaling. Enhances inactivation and does not support calcium-dependent facilitation of voltage-dependent P/Q-type calcium channels. Causes calcium-dependent facilitation and inhibits inactivation of L-type calcium channels by binding to the same sites as calmodulin in the C-terminal domain of CACNA1C, but resulting in an opposit effects on channel function. Suppresses the calcium-dependent inactivation of CACNA1D (By similari [...] (370 aa) | |||
CABP4 | calcium binding protein 4; Involved in normal synaptic function through regulation of Ca(2+) influx and neurotransmitter release in photoreceptor synaptic terminals and in auditory transmission. Modulator of CACNA1D and CACNA1F, suppressing the calcium-dependent inactivation and shifting the activation range to more hyperpolarized voltages (By similarity) (275 aa) | |||
EFCAB13 | EF-hand calcium binding domain 13 (973 aa) | |||
SPATA21 | spermatogenesis associated 21; Involved in the differentiation of haploid spermatids (By similarity) (469 aa) | |||
NOS1 | nitric oxide synthase 1 (neuronal); Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. Probably has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR (1468 aa) | |||
CALM1 | calmodulin 1 (phosphorylase kinase, delta) (149 aa) | |||
RYR1 | ryanodine receptor 1 (skeletal); Calcium channel that mediates the release of Ca(2+) from the sarcoplasmic reticulum into the cytoplasm and thereby plays a key role in triggering muscle contraction following depolarization of T-tubules. Repeated very high-level exercise increases the open probability of the channel and leads to Ca(2+) leaking into the cytoplasm. Can also mediate the release of Ca(2+) from intracellular stores in neurons, and may thereby promote prolonged Ca(2+) signaling in the brain. Required for normal embryonic development of muscle fibers and skeletal muscle. Requi [...] (5038 aa) | |||
SCGN | secretagogin, EF-hand calcium binding protein (276 aa) | |||
ASPH | aspartate beta-hydroxylase (758 aa) | |||
CALN1 | calneuron 1; Negatively regulates Golgi-to-plasma membrane trafficking by interacting with PI4KB and inhibiting its activity (By similarity). May play a role in the physiology of neurons and is potentially important in memory and learning (261 aa) | |||
EFCAB9 | EF-hand calcium binding domain 9 (197 aa) | |||
EFCAB3 | EF-hand calcium binding domain 3 (490 aa) | |||
CALML4 | calmodulin-like 4 (196 aa) |