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STRINGSTRING
CPA6 CPA6 CPA2 CPA2 APLP2 APLP2 CPB2 CPB2 CELA2A CELA2A CPA1 CPA1 CELA3A CELA3A CPA3 CPA3 CELA3B CELA3B CPB1 CPB1 CPA4 CPA4 SERPINA11 SERPINA11 CPA5 CPA5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
CPA1carboxypeptidase A1 (pancreatic) (419 aa)
CPB2carboxypeptidase B2 (plasma); Cleaves C-terminal arginine or lysine residues from biologically active peptides such as kinins or anaphylatoxins in the circulation thereby regulating their activities. Down- regulates fibrinolysis by removing C-terminal lysine residues from fibrin that has already been partially degraded by plasmin (423 aa)
CPA2carboxypeptidase A2 (pancreatic) (419 aa)
CPA4carboxypeptidase A4; Metalloprotease that could be involved in the histone hyperacetylation pathway (421 aa)
APLP2amyloid beta (A4) precursor-like protein 2; May play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5’-GTCACATG-3’(CDEI box). Inhibits trypsin, chymotrypsin, plasmin, factor XIA and plasma and glandular kallikrein. Modulates the Cu/Zn nitric oxide-catalyzed autodegradation of GPC1 heparan sulfate side chains in fibroblasts (By similarity) (763 aa)
CPB1carboxypeptidase B1 (tissue) (417 aa)
CELA3Achymotrypsin-like elastase family, member 3A; Efficient protease with alanine specificity but only little elastolytic activity (270 aa)
CPA3carboxypeptidase A3 (mast cell) (417 aa)
CPA6carboxypeptidase A6; May be involved in the proteolytic inactivation of enkephalins and neurotensin in some brain areas. May convert inactive angiotensin I into the biologically active angiotensin II (437 aa)
SERPINA11serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 11 (422 aa)
CELA3Bchymotrypsin-like elastase family, member 3B; Efficient protease with alanine specificity but only little elastolytic activity (270 aa)
CPA5carboxypeptidase A5 (436 aa)
CELA2Achymotrypsin-like elastase family, member 2A; Acts upon elastin (269 aa)
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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