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STRINGSTRING
HMG20A HMG20A H2AFX H2AFX HADH HADH ACAA1 ACAA1 EHHADH EHHADH ECHS1 ECHS1 HADHA HADHA RPS5 RPS5 UBC UBC ACOT1 ACOT1 DAP3 DAP3 MRPS5 MRPS5 MRPS15 MRPS15 HIBCH HIBCH MRPS35 MRPS35 HIBADH HIBADH MRPS10 MRPS10 MRPS9 MRPS9 SOD2 SOD2 MRPS16 MRPS16 METTL17 METTL17 C12orf10 C12orf10 MRPS2 MRPS2 MRPS7 MRPS7 IRF2BPL IRF2BPL PAICS PAICS
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
MRPS10mitochondrial ribosomal protein S10 (201 aa)
MRPS35mitochondrial ribosomal protein S35 (323 aa)
RPS5ribosomal protein S5 (204 aa)
EHHADHenoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase (723 aa)
IRF2BPLinterferon regulatory factor 2 binding protein-like; May contribute to the control of female reproductive function (By similarity). May play a role in gene transcription by transactivating GNRH1 promoter and repressing PENK promoter (796 aa)
MRPS2mitochondrial ribosomal protein S2 (296 aa)
MRPS7mitochondrial ribosomal protein S7 (242 aa)
MRPS9mitochondrial ribosomal protein S9 (396 aa)
HIBADH3-hydroxyisobutyrate dehydrogenase (336 aa)
C12orf10chromosome 12 open reading frame 10 (376 aa)
MRPS5mitochondrial ribosomal protein S5 (430 aa)
ACOT1acyl-CoA thioesterase 1; Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. Active towards fatty acyl-CoA with chain-lengths of C12-C16 (By similarity) (421 aa)
ACAA1acetyl-CoA acyltransferase 1 (424 aa)
HMG20Ahigh mobility group 20A; Plays a role in neuronal differentiation as chromatin- associated protein. Acts as inhibitor of HMG20B. Overcomes the repressive effects of the neuronal silencer REST and induces the activation of neuronal-specific genes. Involved in the recruitment of the histone methyltransferase MLL and consequent increased methylation of histone H3 lysine 4 (By similarity) (347 aa)
DAP3death associated protein 3; Involved in mediating interferon-gamma-induced cell death (398 aa)
UBCubiquitin C (685 aa)
HIBCH3-hydroxyisobutyryl-CoA hydrolase; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite. Has high activity toward isobutyryl-CoA. Could be an isobutyryl-CoA dehydrogenase that functions in valine catabolism. Also hydrolyzes 3-hydroxypropanoyl-CoA (386 aa)
SOD2superoxide dismutase 2, mitochondrial; Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) (222 aa)
ECHS1enoyl CoA hydratase, short chain, 1, mitochondrial; Straight-chain enoyl-CoA thioesters from C4 up to at least C16 are processed, although with decreasing catalytic rate (290 aa)
MRPS16mitochondrial ribosomal protein S16 (137 aa)
MRPS15mitochondrial ribosomal protein S15 (257 aa)
H2AFXH2A histone family, member X; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Required for checkpoint-mediated arrest of cell cycle progression in resp [...] (143 aa)
HADHAhydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit; Bifunctional subunit (763 aa)
METTL17methyltransferase like 17; May be a component of the mitochondrial small ribosomal subunit (By similarity) (478 aa)
PAICSphosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase (432 aa)
HADHhydroxyacyl-CoA dehydrogenase; Plays an essential role in the mitochondrial beta- oxidation of short chain fatty acids. Exerts it highest activity toward 3-hydroxybutyryl-CoA (331 aa)
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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