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GADD45G | growth arrest and DNA-damage-inducible, gamma; Involved in the regulation of growth and apoptosis. Mediates activation of stress-responsive MTK1/MEKK4 MAPKKK (159 aa) | |||
KLC4 | kinesin light chain 4; Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport. The light chain may function in coupling of cargo to the heavy chain or in the modulation of its ATPase activity (By similarity) (637 aa) | |||
MID2 | midline 2 (735 aa) | |||
MFAP1 | microfibrillar-associated protein 1; Component of the elastin-associated microfibrils (439 aa) | |||
HAUS1 | HAUS augmin-like complex, subunit 1; Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex (278 aa) | |||
MYO15B | myosin XVB pseudogene (487 aa) | |||
TRAPPC2L | trafficking protein particle complex 2-like; May play a role in vesicular transport from endoplasmic reticulum to Golgi (140 aa) | |||
ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2; Specifically recognizes the xenobiotic response element (XRE) (717 aa) | |||
HDDC3 | HD domain containing 3; ppGpp hydrolyzing enzyme involved in starvation response (140 aa) | |||
MAGEA2B | melanoma antigen family A, 2B (314 aa) | |||
PKN1 | protein kinase N1; PKC-related serine/threonine-protein kinase involved in various processes such as regulation of the intermediate filaments of the actin cytoskeleton, cell migration, tumor cell invasion and transcription regulation. Regulates the cytoskeletal network by phosphorylating proteins such as VIM and neurofilament proteins NEFH, NEFL and NEFM, leading to inhibit their polymerization. Phosphorylates ’Ser-575’, ’Ser-637’ and ’Ser-669’ of MAPT/Tau, lowering its ability to bind to microtubules, resulting in disruption of tubulin assembly. Acts as a key coactivator of androgen r [...] (948 aa) | |||
UBC | ubiquitin C (685 aa) | |||
TXLNB | taxilin beta; Promotes motor nerve regeneration (By similarity). May be involved in intracellular vesicle traffic (684 aa) | |||
CEP57L1 | centrosomal protein 57kDa-like 1; Centrosomal protein which may be required for microtubule attachment to centrosomes (By similarity) (460 aa) | |||
EXOC8 | exocyst complex component 8; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane (725 aa) | |||
DISC1 | disrupted in schizophrenia 1 (755 aa) | |||
SNAP47 | synaptosomal-associated protein, 47kDa (464 aa) | |||
CEP55 | centrosomal protein 55kDa; Plays a role in mitotic exit and cytokinesis. Not required for microtubule nucleation. Recruits PDCD6IP and TSG101 to midbody during cytokinesis (464 aa) | |||
GOLGA1 | golgin A1; Probably involved in maintaining Golgi structure (767 aa) | |||
TXLNA | taxilin alpha (546 aa) | |||
KATNAL1 | katanin p60 subunit A-like 1; Regulates microtubule dynamics in Sertoli cells, a process that is essential for spermiogenesis and male fertility. Severs microtubules in an ATP-dependent manner, promoting rapid reorganization of cellular microtubule arrays (By similarity) (490 aa) | |||
SNAPC3 | small nuclear RNA activating complex, polypeptide 3, 50kDa; Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. Recruits TBP and BRF2 to the U6 snRNA TATA box (411 aa) | |||
FAM161A | family with sequence similarity 161, member A; Involved in ciliogenesis (716 aa) | |||
ELAVL1 | ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R); Involved in 3’-UTR ARE-mediated MYC stabilization. Binds avidly to the AU-rich element in FOS and IL3/interleukin-3 mRNAs. In the case of the FOS AU-rich element, HUR binds to a core element of 27 nucleotides that contain AUUUA, AUUUUA and AUUUUUA motifs. Binds preferentially to the 5’-UUUU[AG]UUU-3’ motif in vitro (326 aa) | |||
TCEB3 | transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A); SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A is transcriptionally active and its transcription activity is strongly enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex) (798 aa) |