9 items (Homo sapiens) - STRING network view

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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protein of unknown 3D structure

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Your Input:
	GGA3	golgi-associated, gamma adaptin ear containing, ARF binding protein 3; Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates the ARF- dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (AC-LL) motif (723 aa)
	GGA2	golgi-associated, gamma adaptin ear containing, ARF binding protein 2; Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates the ARF- dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (AC-LL) motif (613 aa)
	GGA1	golgi-associated, gamma adaptin ear containing, ARF binding protein 1 (639 aa)
	UBC	ubiquitin C (685 aa)
	CUEDC1	CUE domain containing 1 (386 aa)
	IKBKG	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma; Regulatory subunit of the IKK core complex which phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Its binding to scaffolding polyubiquitin seems to play a role in IKK activation by multiple signaling receptor pathways. However, the specific type of polyubiquitin recognized upon cell stimulation (either ’Lys-63’- linked or linear polyubiquitin) and its functional importance is reported conflictingly. Als [...] (487 aa)
	TOM1L2	target of myb1-like 2 (chicken); Probable role in protein transport. May regulate growth factor-induced mitogenic signaling (507 aa)
	TOM1	target of myb1 (chicken); May be involved in intracellular trafficking. Probable association with membranes (493 aa)
	TOM1L1	target of myb1 (chicken)-like 1; Probable adapter protein involved in signaling pathways. Interacts with the SH2 and SH3 domains of various signaling proteins when it is phosphorylated. May promote FYN activation, possibly by disrupting intramolecular SH3-dependent interactions (By similarity) (476 aa)

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CUEDC1	TOM1	ENSP00000353373	ENSP00000413697	CUE domain containing 1	target of myb1 (chicken); May be involved in intracellular trafficking. Probable association with membranes	0.424
CUEDC1	TOM1L2	ENSP00000353373	ENSP00000368818	CUE domain containing 1	target of myb1-like 2 (chicken); Probable role in protein transport. May regulate growth factor-induced mitogenic signaling	0.584
CUEDC1	UBC	ENSP00000353373	ENSP00000344818	CUE domain containing 1	ubiquitin C	0.630
GGA1	GGA2	ENSP00000341344	ENSP00000311962	golgi-associated, gamma adaptin ear containing, ARF binding protein 1	golgi-associated, gamma adaptin ear containing, ARF binding protein 2; Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates the ARF- dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (AC-LL) motif	0.736
GGA1	GGA3	ENSP00000341344	ENSP00000245541	golgi-associated, gamma adaptin ear containing, ARF binding protein 1	golgi-associated, gamma adaptin ear containing, ARF binding protein 3; Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates the ARF- dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (AC-LL) motif	0.743
GGA1	UBC	ENSP00000341344	ENSP00000344818	golgi-associated, gamma adaptin ear containing, ARF binding protein 1	ubiquitin C	0.997
GGA2	GGA1	ENSP00000311962	ENSP00000341344	golgi-associated, gamma adaptin ear containing, ARF binding protein 2; Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates the ARF- dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (AC-LL) motif	golgi-associated, gamma adaptin ear containing, ARF binding protein 1	0.736
GGA2	GGA3	ENSP00000311962	ENSP00000245541	golgi-associated, gamma adaptin ear containing, ARF binding protein 2; Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates the ARF- dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (AC-LL) motif	golgi-associated, gamma adaptin ear containing, ARF binding protein 3; Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates the ARF- dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (AC-LL) motif	0.758
GGA2	UBC	ENSP00000311962	ENSP00000344818	golgi-associated, gamma adaptin ear containing, ARF binding protein 2; Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates the ARF- dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (AC-LL) motif	ubiquitin C	0.804
GGA3	GGA1	ENSP00000245541	ENSP00000341344	golgi-associated, gamma adaptin ear containing, ARF binding protein 3; Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates the ARF- dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (AC-LL) motif	golgi-associated, gamma adaptin ear containing, ARF binding protein 1	0.743
GGA3	GGA2	ENSP00000245541	ENSP00000311962	golgi-associated, gamma adaptin ear containing, ARF binding protein 3; Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates the ARF- dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (AC-LL) motif	golgi-associated, gamma adaptin ear containing, ARF binding protein 2; Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates the ARF- dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (AC-LL) motif	0.758
GGA3	UBC	ENSP00000245541	ENSP00000344818	golgi-associated, gamma adaptin ear containing, ARF binding protein 3; Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates the ARF- dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (AC-LL) motif	ubiquitin C	0.999
IKBKG	UBC	ENSP00000358622	ENSP00000344818	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma; Regulatory subunit of the IKK core complex which phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Its binding to scaffolding polyubiquitin seems to play a role in IKK activation by multiple signaling receptor pathways. However, the specific type of polyubiquitin recognized upon cell stimulation (either ’Lys-63’- linked or linear polyubiquitin) and its functional importance is reported conflictingly. Als [...]	ubiquitin C	0.999
TOM1	CUEDC1	ENSP00000413697	ENSP00000353373	target of myb1 (chicken); May be involved in intracellular trafficking. Probable association with membranes	CUE domain containing 1	0.424
TOM1	TOM1L1	ENSP00000413697	ENSP00000460823	target of myb1 (chicken); May be involved in intracellular trafficking. Probable association with membranes	target of myb1 (chicken)-like 1; Probable adapter protein involved in signaling pathways. Interacts with the SH2 and SH3 domains of various signaling proteins when it is phosphorylated. May promote FYN activation, possibly by disrupting intramolecular SH3-dependent interactions (By similarity)	0.630
TOM1	UBC	ENSP00000413697	ENSP00000344818	target of myb1 (chicken); May be involved in intracellular trafficking. Probable association with membranes	ubiquitin C	0.998
TOM1L1	TOM1	ENSP00000460823	ENSP00000413697	target of myb1 (chicken)-like 1; Probable adapter protein involved in signaling pathways. Interacts with the SH2 and SH3 domains of various signaling proteins when it is phosphorylated. May promote FYN activation, possibly by disrupting intramolecular SH3-dependent interactions (By similarity)	target of myb1 (chicken); May be involved in intracellular trafficking. Probable association with membranes	0.630
TOM1L1	UBC	ENSP00000460823	ENSP00000344818	target of myb1 (chicken)-like 1; Probable adapter protein involved in signaling pathways. Interacts with the SH2 and SH3 domains of various signaling proteins when it is phosphorylated. May promote FYN activation, possibly by disrupting intramolecular SH3-dependent interactions (By similarity)	ubiquitin C	0.912
TOM1L2	CUEDC1	ENSP00000368818	ENSP00000353373	target of myb1-like 2 (chicken); Probable role in protein transport. May regulate growth factor-induced mitogenic signaling	CUE domain containing 1	0.584
TOM1L2	UBC	ENSP00000368818	ENSP00000344818	target of myb1-like 2 (chicken); Probable role in protein transport. May regulate growth factor-induced mitogenic signaling	ubiquitin C	0.976

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