node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AZGP1 | B2M | ENSP00000292401 | ENSP00000452780 | alpha-2-glycoprotein 1, zinc-binding; Stimulates lipid degradation in adipocytes and causes the extensive fat losses associated with some advanced cancers. May bind polyunsaturated fatty acids | beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity) | 0.610 |
AZGP1 | MR1 | ENSP00000292401 | ENSP00000356552 | alpha-2-glycoprotein 1, zinc-binding; Stimulates lipid degradation in adipocytes and causes the extensive fat losses associated with some advanced cancers. May bind polyunsaturated fatty acids | major histocompatibility complex, class I-related | 0.402 |
B2M | AZGP1 | ENSP00000452780 | ENSP00000292401 | beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity) | alpha-2-glycoprotein 1, zinc-binding; Stimulates lipid degradation in adipocytes and causes the extensive fat losses associated with some advanced cancers. May bind polyunsaturated fatty acids | 0.610 |
B2M | CD8A | ENSP00000452780 | ENSP00000283635 | beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity) | CD8a molecule; Identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing. CD8 alpha chains binds to class I MHC molecules alpha-3 domains | 0.998 |
B2M | HFE | ENSP00000452780 | ENSP00000417404 | beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity) | hemochromatosis | 0.998 |
B2M | HLA-A | ENSP00000452780 | ENSP00000366005 | beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity) | major histocompatibility complex, class I, A; Involved in the presentation of foreign antigens to the immune system (By similarity) | 0.998 |
B2M | HLA-B | ENSP00000452780 | ENSP00000399168 | beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity) | major histocompatibility complex, class I, B; Involved in the presentation of foreign antigens to the immune system (By similarity) | 0.999 |
B2M | HLA-C | ENSP00000452780 | ENSP00000365402 | beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity) | major histocompatibility complex, class I, C; Involved in the presentation of foreign antigens to the immune system (By similarity) | 0.986 |
B2M | HLA-G | ENSP00000452780 | ENSP00000353472 | beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity) | major histocompatibility complex, class I, G; Involved in the presentation of foreign antigens to the immune system. Plays a role in maternal tolerance of the fetus by mediating protection from the deleterious effects of natural killer cells, cytotoxic T-lymphocytes, macrophages and mononuclear cells | 0.924 |
B2M | KIR2DL4 | ENSP00000452780 | ENSP00000339634 | beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity) | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 | 0.900 |
B2M | KLRD1 | ENSP00000452780 | ENSP00000338130 | beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity) | killer cell lectin-like receptor subfamily D, member 1; Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells | 0.943 |
B2M | LILRB1 | ENSP00000452780 | ENSP00000315997 | beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity) | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1; Receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles. Receptor for H301/UL18, a human cytomegalovirus class I MHC homolog. Ligand binding results in inhibitory signals and down-regulation of the immune response. Engagement of LILRB1 present on natural killer cells or T-cells by class I MHC molecules protects the target cells from lysis. Interaction with HLA-B or HLA-E leads to inhibition of the signal triggered by FCER1A and inhibits serotonin rel [...] | 0.564 |
B2M | LILRB2 | ENSP00000452780 | ENSP00000375629 | beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity) | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2; Receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles. Involved in the down-regulation of the immune response and the development of tolerance. Competes with CD8A for binding to class I MHC antigens. Inhibits FCGR1A-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions | 0.920 |
B2M | MR1 | ENSP00000452780 | ENSP00000356552 | beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity) | major histocompatibility complex, class I-related | 0.985 |
CD8A | B2M | ENSP00000283635 | ENSP00000452780 | CD8a molecule; Identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing. CD8 alpha chains binds to class I MHC molecules alpha-3 domains | beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity) | 0.998 |
CD8A | HLA-A | ENSP00000283635 | ENSP00000366005 | CD8a molecule; Identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing. CD8 alpha chains binds to class I MHC molecules alpha-3 domains | major histocompatibility complex, class I, A; Involved in the presentation of foreign antigens to the immune system (By similarity) | 0.987 |
CD8A | HLA-B | ENSP00000283635 | ENSP00000399168 | CD8a molecule; Identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing. CD8 alpha chains binds to class I MHC molecules alpha-3 domains | major histocompatibility complex, class I, B; Involved in the presentation of foreign antigens to the immune system (By similarity) | 0.992 |
CD8A | HLA-C | ENSP00000283635 | ENSP00000365402 | CD8a molecule; Identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing. CD8 alpha chains binds to class I MHC molecules alpha-3 domains | major histocompatibility complex, class I, C; Involved in the presentation of foreign antigens to the immune system (By similarity) | 0.992 |
CD8A | HLA-G | ENSP00000283635 | ENSP00000353472 | CD8a molecule; Identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing. CD8 alpha chains binds to class I MHC molecules alpha-3 domains | major histocompatibility complex, class I, G; Involved in the presentation of foreign antigens to the immune system. Plays a role in maternal tolerance of the fetus by mediating protection from the deleterious effects of natural killer cells, cytotoxic T-lymphocytes, macrophages and mononuclear cells | 0.967 |
CD8A | KLRD1 | ENSP00000283635 | ENSP00000338130 | CD8a molecule; Identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing. CD8 alpha chains binds to class I MHC molecules alpha-3 domains | killer cell lectin-like receptor subfamily D, member 1; Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells | 0.948 |