node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CAD | CDS1 | ENSP00000264705 | ENSP00000295887 | carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase; This protein is a "fusion" protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase) | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1; Provides CDP-diacylglycerol an important precursor for the synthesis of phosphatidylinositol (PtdIns), phosphatidylglycerol, and cardiolipin. Overexpression may amplify cellular signaling responses from cytokines. May also play an important role in the signal transduction mechanism of retina and neural cells | 0.487 |
CAD | CDS2 | ENSP00000264705 | ENSP00000419879 | carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase; This protein is a "fusion" protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase) | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 | 0.492 |
CAD | CPS1 | ENSP00000264705 | ENSP00000402608 | carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase; This protein is a "fusion" protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase) | carbamoyl-phosphate synthase 1, mitochondrial; Involved in the urea cycle of ureotelic animals where the enzyme plays an important role in removing excess ammonia from the cell | 0.999 |
CAD | HSPA1A | ENSP00000264705 | ENSP00000364802 | carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase; This protein is a "fusion" protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase) | heat shock 70kDa protein 1A | 0.681 |
CAD | SLC35F1 | ENSP00000264705 | ENSP00000353557 | carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase; This protein is a "fusion" protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase) | solute carrier family 35, member F1; Putative solute transporter (Potential) | 0.515 |
CDS1 | CAD | ENSP00000295887 | ENSP00000264705 | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1; Provides CDP-diacylglycerol an important precursor for the synthesis of phosphatidylinositol (PtdIns), phosphatidylglycerol, and cardiolipin. Overexpression may amplify cellular signaling responses from cytokines. May also play an important role in the signal transduction mechanism of retina and neural cells | carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase; This protein is a "fusion" protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase) | 0.487 |
CDS2 | CAD | ENSP00000419879 | ENSP00000264705 | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 | carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase; This protein is a "fusion" protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase) | 0.492 |
CPS1 | CAD | ENSP00000402608 | ENSP00000264705 | carbamoyl-phosphate synthase 1, mitochondrial; Involved in the urea cycle of ureotelic animals where the enzyme plays an important role in removing excess ammonia from the cell | carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase; This protein is a "fusion" protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase) | 0.999 |
CPS1 | HSPA1A | ENSP00000402608 | ENSP00000364802 | carbamoyl-phosphate synthase 1, mitochondrial; Involved in the urea cycle of ureotelic animals where the enzyme plays an important role in removing excess ammonia from the cell | heat shock 70kDa protein 1A | 0.504 |
HSPA1A | CAD | ENSP00000364802 | ENSP00000264705 | heat shock 70kDa protein 1A | carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase; This protein is a "fusion" protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase) | 0.681 |
HSPA1A | CPS1 | ENSP00000364802 | ENSP00000402608 | heat shock 70kDa protein 1A | carbamoyl-phosphate synthase 1, mitochondrial; Involved in the urea cycle of ureotelic animals where the enzyme plays an important role in removing excess ammonia from the cell | 0.504 |
HSPA1A | SEC61A1 | ENSP00000364802 | ENSP00000243253 | heat shock 70kDa protein 1A | Sec61 alpha 1 subunit (S. cerevisiae) | 0.491 |
HSPA1A | SEC61A2 | ENSP00000364802 | ENSP00000298428 | heat shock 70kDa protein 1A | Sec61 alpha 2 subunit (S. cerevisiae); Appears to play a crucial role in the insertion of secretory and membrane polypeptides into the ER. It is required for assembly of membrane and secretory proteins. Found to be tightly associated with membrane-bound ribosomes, either directly or through adaptor proteins (By similarity) | 0.491 |
SEC61A1 | HSPA1A | ENSP00000243253 | ENSP00000364802 | Sec61 alpha 1 subunit (S. cerevisiae) | heat shock 70kDa protein 1A | 0.491 |
SEC61A1 | SEC61A2 | ENSP00000243253 | ENSP00000298428 | Sec61 alpha 1 subunit (S. cerevisiae) | Sec61 alpha 2 subunit (S. cerevisiae); Appears to play a crucial role in the insertion of secretory and membrane polypeptides into the ER. It is required for assembly of membrane and secretory proteins. Found to be tightly associated with membrane-bound ribosomes, either directly or through adaptor proteins (By similarity) | 0.900 |
SEC61A2 | HSPA1A | ENSP00000298428 | ENSP00000364802 | Sec61 alpha 2 subunit (S. cerevisiae); Appears to play a crucial role in the insertion of secretory and membrane polypeptides into the ER. It is required for assembly of membrane and secretory proteins. Found to be tightly associated with membrane-bound ribosomes, either directly or through adaptor proteins (By similarity) | heat shock 70kDa protein 1A | 0.491 |
SEC61A2 | SEC61A1 | ENSP00000298428 | ENSP00000243253 | Sec61 alpha 2 subunit (S. cerevisiae); Appears to play a crucial role in the insertion of secretory and membrane polypeptides into the ER. It is required for assembly of membrane and secretory proteins. Found to be tightly associated with membrane-bound ribosomes, either directly or through adaptor proteins (By similarity) | Sec61 alpha 1 subunit (S. cerevisiae) | 0.900 |
SLC35F1 | CAD | ENSP00000353557 | ENSP00000264705 | solute carrier family 35, member F1; Putative solute transporter (Potential) | carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase; This protein is a "fusion" protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase) | 0.515 |