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RPL27 RPL27 UBC UBC SLC25A17 SLC25A17 DHX15 DHX15 ACIN1 ACIN1 B4GALT3 B4GALT3 B4GALT1 B4GALT1 FUT8 FUT8 MGAT4A MGAT4A MGAT2 MGAT2 B4GALT2 B4GALT2 MGAT4B MGAT4B MGAT3 MGAT3
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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small nodes:
protein of unknown 3D structure
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large nodes:
some 3D structure is known or predicted
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colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
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Predicted Interactions
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RPL27ribosomal protein L27 (136 aa)
ACIN1apoptotic chromatin condensation inducer 1; Component of a splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of a few core proteins and several more peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Induces apoptotic chromatin condensation after activation by CASP3. Regulates cyclin A1, but not cyclin A2, expression in leukemia cells (1341 aa)
MGAT4Amannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A; Glycosyltransferase that participates in the transfer of N-acetylglucosamine (GlcNAc) to the core mannose residues of N- linked glycans. Catalyzes the formation of the GlcNAcbeta1-4 branch on the GlcNAcbeta1-2Manalpha1-3 arm of the core structure of N-linked glycans. Essential for the production of tri- and tetra-antennary N-linked sugar chains. Involved in glucose transport by mediating SLC2A2/GLUT2 glycosylation, thereby controlling cell-surface expression of SLC2A2 in pancreatic beta cells (535 aa)
MGAT2mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase; Catalyzes an essential step in the conversion of oligo- mannose to complex N-glycans (447 aa)
B4GALT2UDP-Gal-betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 (401 aa)
B4GALT3UDP-Gal-betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3; Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids (393 aa)
DHX15DEAH (Asp-Glu-Ala-His) box polypeptide 15; Pre-mRNA processing factor involved in disassembly of spliceosomes after the release of mature mRNA (By similarity) (795 aa)
MGAT4Bmannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B; Glycosyltransferase that participates in the transfer of N-acetylglucosamine (GlcNAc) to the core mannose residues of N- linked glycans. Catalyzes the formation of the GlcNAcbeta1-4 branch on the GlcNAcbeta1-2Manalpha1-3 arm of the core structure of N-linked glycans. Essential for the production of tri- and tetra-antennary N-linked sugar chains. Has lower affinities for donors or acceptors than MGAT4A, suggesting that, under physiological conditions, it is not the main contributor in N- glycan biosy [...] (563 aa)
UBCubiquitin C (685 aa)
MGAT3mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase; It is involved in the regulation of the biosynthesis and biological function of glycoprotein oligosaccharides. Catalyzes the addition of N-acetylglucosamine in beta 1-4 linkage to the beta-linked mannose of the trimannosyl core of N-linked sugar chains. It is one of the most important enzymes involved in the regulation of the biosynthesis of glycoprotein oligosaccharides (533 aa)
FUT8fucosyltransferase 8 (alpha (1,6) fucosyltransferase); Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans (By similarity) (575 aa)
B4GALT1UDP-Gal-betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 (398 aa)
SLC25A17solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17; Peroxisomal transporter for multiple cofactors like coenzyme A (CoA), flavin adenine dinucleotide (FAD), flavin mononucleotide (FMN) and nucleotide adenosine monophosphate (AMP), and to a lesser extend for nicotinamide adenine dinucleotide (NAD(+)), adenosine diphosphate (ADP) and adenosine 3’,5’- diphosphate (PAP). May catalyze the transport of free CoA, FAD and NAD(+) from the cytosol into the peroxisomal matrix by a counter- exchange mechanism. Inhibited by pyridoxal 5’-phosphate and ba [...] (307 aa)
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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