11 items (Homo sapiens) - STRING network view

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Your Input:
	DLD	dihydrolipoamide dehydrogenase; Lipoamide dehydrogenase is a component of the glycine cleavage system as well as of the alpha-ketoacid dehydrogenase complexes. Involved in the hyperactivation of spermatazoa during capacitation and in the spermatazoal acrosome reaction (509 aa)
	PDHX	pyruvate dehydrogenase complex, component X; Required for anchoring dihydrolipoamide dehydrogenase (E3) to the dihydrolipoamide transacetylase (E2) core of the pyruvate dehydrogenase complexes of eukaryotes. This specific binding is essential for a functional PDH complex (501 aa)
	MPC2	mitochondrial pyruvate carrier 2; Mediates the uptake of pyruvate into mitochondria (127 aa)
	PDHB	pyruvate dehydrogenase (lipoamide) beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle (359 aa)
	GPD2	glycerol-3-phosphate dehydrogenase 2 (mitochondrial) (727 aa)
	ME2	malic enzyme 2, NAD(+)-dependent, mitochondrial (584 aa)
	UBC	ubiquitin C (685 aa)
	ME3	malic enzyme 3, NADP(+)-dependent, mitochondrial (604 aa)
	MPC1	mitochondrial pyruvate carrier 1; Mediates the uptake of pyruvate into mitochondria (109 aa)
	ME1	malic enzyme 1, NADP(+)-dependent, cytosolic (572 aa)
	PDHA1	pyruvate dehydrogenase (lipoamide) alpha 1 (428 aa)

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DLD	MPC1	ENSP00000205402	ENSP00000354223	dihydrolipoamide dehydrogenase; Lipoamide dehydrogenase is a component of the glycine cleavage system as well as of the alpha-ketoacid dehydrogenase complexes. Involved in the hyperactivation of spermatazoa during capacitation and in the spermatazoal acrosome reaction	mitochondrial pyruvate carrier 1; Mediates the uptake of pyruvate into mitochondria	0.903
DLD	MPC2	ENSP00000205402	ENSP00000271373	dihydrolipoamide dehydrogenase; Lipoamide dehydrogenase is a component of the glycine cleavage system as well as of the alpha-ketoacid dehydrogenase complexes. Involved in the hyperactivation of spermatazoa during capacitation and in the spermatazoal acrosome reaction	mitochondrial pyruvate carrier 2; Mediates the uptake of pyruvate into mitochondria	0.903
DLD	PDHA1	ENSP00000205402	ENSP00000369134	dihydrolipoamide dehydrogenase; Lipoamide dehydrogenase is a component of the glycine cleavage system as well as of the alpha-ketoacid dehydrogenase complexes. Involved in the hyperactivation of spermatazoa during capacitation and in the spermatazoal acrosome reaction	pyruvate dehydrogenase (lipoamide) alpha 1	0.993
DLD	PDHB	ENSP00000205402	ENSP00000307241	dihydrolipoamide dehydrogenase; Lipoamide dehydrogenase is a component of the glycine cleavage system as well as of the alpha-ketoacid dehydrogenase complexes. Involved in the hyperactivation of spermatazoa during capacitation and in the spermatazoal acrosome reaction	pyruvate dehydrogenase (lipoamide) beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle	0.999
DLD	PDHX	ENSP00000205402	ENSP00000227868	dihydrolipoamide dehydrogenase; Lipoamide dehydrogenase is a component of the glycine cleavage system as well as of the alpha-ketoacid dehydrogenase complexes. Involved in the hyperactivation of spermatazoa during capacitation and in the spermatazoal acrosome reaction	pyruvate dehydrogenase complex, component X; Required for anchoring dihydrolipoamide dehydrogenase (E3) to the dihydrolipoamide transacetylase (E2) core of the pyruvate dehydrogenase complexes of eukaryotes. This specific binding is essential for a functional PDH complex	0.999
DLD	UBC	ENSP00000205402	ENSP00000344818	dihydrolipoamide dehydrogenase; Lipoamide dehydrogenase is a component of the glycine cleavage system as well as of the alpha-ketoacid dehydrogenase complexes. Involved in the hyperactivation of spermatazoa during capacitation and in the spermatazoal acrosome reaction	ubiquitin C	0.863
GPD2	UBC	ENSP00000308610	ENSP00000344818	glycerol-3-phosphate dehydrogenase 2 (mitochondrial)	ubiquitin C	0.440
ME1	MPC1	ENSP00000358719	ENSP00000354223	malic enzyme 1, NADP(+)-dependent, cytosolic	mitochondrial pyruvate carrier 1; Mediates the uptake of pyruvate into mitochondria	0.566
ME1	PDHA1	ENSP00000358719	ENSP00000369134	malic enzyme 1, NADP(+)-dependent, cytosolic	pyruvate dehydrogenase (lipoamide) alpha 1	0.925
ME1	PDHB	ENSP00000358719	ENSP00000307241	malic enzyme 1, NADP(+)-dependent, cytosolic	pyruvate dehydrogenase (lipoamide) beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle	0.929
ME1	PDHX	ENSP00000358719	ENSP00000227868	malic enzyme 1, NADP(+)-dependent, cytosolic	pyruvate dehydrogenase complex, component X; Required for anchoring dihydrolipoamide dehydrogenase (E3) to the dihydrolipoamide transacetylase (E2) core of the pyruvate dehydrogenase complexes of eukaryotes. This specific binding is essential for a functional PDH complex	0.430
ME1	UBC	ENSP00000358719	ENSP00000344818	malic enzyme 1, NADP(+)-dependent, cytosolic	ubiquitin C	0.818
ME2	MPC1	ENSP00000321070	ENSP00000354223	malic enzyme 2, NAD(+)-dependent, mitochondrial	mitochondrial pyruvate carrier 1; Mediates the uptake of pyruvate into mitochondria	0.566
ME2	PDHA1	ENSP00000321070	ENSP00000369134	malic enzyme 2, NAD(+)-dependent, mitochondrial	pyruvate dehydrogenase (lipoamide) alpha 1	0.925
ME2	PDHB	ENSP00000321070	ENSP00000307241	malic enzyme 2, NAD(+)-dependent, mitochondrial	pyruvate dehydrogenase (lipoamide) beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle	0.923
ME2	PDHX	ENSP00000321070	ENSP00000227868	malic enzyme 2, NAD(+)-dependent, mitochondrial	pyruvate dehydrogenase complex, component X; Required for anchoring dihydrolipoamide dehydrogenase (E3) to the dihydrolipoamide transacetylase (E2) core of the pyruvate dehydrogenase complexes of eukaryotes. This specific binding is essential for a functional PDH complex	0.430
ME2	UBC	ENSP00000321070	ENSP00000344818	malic enzyme 2, NAD(+)-dependent, mitochondrial	ubiquitin C	0.430
ME3	MPC1	ENSP00000352657	ENSP00000354223	malic enzyme 3, NADP(+)-dependent, mitochondrial	mitochondrial pyruvate carrier 1; Mediates the uptake of pyruvate into mitochondria	0.566
ME3	PDHA1	ENSP00000352657	ENSP00000369134	malic enzyme 3, NADP(+)-dependent, mitochondrial	pyruvate dehydrogenase (lipoamide) alpha 1	0.925
ME3	PDHB	ENSP00000352657	ENSP00000307241	malic enzyme 3, NADP(+)-dependent, mitochondrial	pyruvate dehydrogenase (lipoamide) beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle	0.926

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