node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EIF1 | EIF1AY | ENSP00000419449 | ENSP00000354722 | eukaryotic translation initiation factor 1; Necessary for scanning and involved in initiation site selection. Promotes the assembly of 48S ribosomal complexes at the authentic initiation codon of a conventional capped mRNA | eukaryotic translation initiation factor 1A, Y-linked; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits (By similarity) | 0.834 |
EIF1 | EIF2S2 | ENSP00000419449 | ENSP00000364119 | eukaryotic translation initiation factor 1; Necessary for scanning and involved in initiation site selection. Promotes the assembly of 48S ribosomal complexes at the authentic initiation codon of a conventional capped mRNA | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a rea [...] | 0.993 |
EIF1 | EIF5 | ENSP00000419449 | ENSP00000216554 | eukaryotic translation initiation factor 1; Necessary for scanning and involved in initiation site selection. Promotes the assembly of 48S ribosomal complexes at the authentic initiation codon of a conventional capped mRNA | eukaryotic translation initiation factor 5; Catalyzes the hydrolysis of GTP bound to the 40S ribosomal initiation complex (40S.mRNA.Met-tRNA[F].eIF-2.GTP) with the subsequent joining of a 60S ribosomal subunit resulting in the release of eIF-2 and the guanine nucleotide. The subsequent joining of a 60S ribosomal subunit results in the formation of a functional 80S initiation complex (80S.mRNA.Met-tRNA[F]) | 0.997 |
EIF1 | EIF5B | ENSP00000419449 | ENSP00000289371 | eukaryotic translation initiation factor 1; Necessary for scanning and involved in initiation site selection. Promotes the assembly of 48S ribosomal complexes at the authentic initiation codon of a conventional capped mRNA | eukaryotic translation initiation factor 5B; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 (By similarity) | 0.978 |
EIF1 | FAU | ENSP00000419449 | ENSP00000431822 | eukaryotic translation initiation factor 1; Necessary for scanning and involved in initiation site selection. Promotes the assembly of 48S ribosomal complexes at the authentic initiation codon of a conventional capped mRNA | Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed | 0.891 |
EIF1 | RPS11 | ENSP00000419449 | ENSP00000270625 | eukaryotic translation initiation factor 1; Necessary for scanning and involved in initiation site selection. Promotes the assembly of 48S ribosomal complexes at the authentic initiation codon of a conventional capped mRNA | ribosomal protein S11 | 0.828 |
EIF1 | RPS13 | ENSP00000419449 | ENSP00000435777 | eukaryotic translation initiation factor 1; Necessary for scanning and involved in initiation site selection. Promotes the assembly of 48S ribosomal complexes at the authentic initiation codon of a conventional capped mRNA | ribosomal protein S13 | 0.801 |
EIF1 | RPS14 | ENSP00000419449 | ENSP00000311028 | eukaryotic translation initiation factor 1; Necessary for scanning and involved in initiation site selection. Promotes the assembly of 48S ribosomal complexes at the authentic initiation codon of a conventional capped mRNA | ribosomal protein S14 | 0.796 |
EIF1 | RPS15 | ENSP00000419449 | ENSP00000467676 | eukaryotic translation initiation factor 1; Necessary for scanning and involved in initiation site selection. Promotes the assembly of 48S ribosomal complexes at the authentic initiation codon of a conventional capped mRNA | ribosomal protein S15 | 0.844 |
EIF1 | RPS15A | ENSP00000419449 | ENSP00000318646 | eukaryotic translation initiation factor 1; Necessary for scanning and involved in initiation site selection. Promotes the assembly of 48S ribosomal complexes at the authentic initiation codon of a conventional capped mRNA | ribosomal protein S15a | 0.845 |
EIF1 | RPS16 | ENSP00000419449 | ENSP00000251453 | eukaryotic translation initiation factor 1; Necessary for scanning and involved in initiation site selection. Promotes the assembly of 48S ribosomal complexes at the authentic initiation codon of a conventional capped mRNA | ribosomal protein S16 | 0.778 |
EIF1 | RPS19 | ENSP00000419449 | ENSP00000470004 | eukaryotic translation initiation factor 1; Necessary for scanning and involved in initiation site selection. Promotes the assembly of 48S ribosomal complexes at the authentic initiation codon of a conventional capped mRNA | ribosomal protein S19; Required for pre-rRNA processing and maturation of 40S ribosomal subunits | 0.769 |
EIF1 | RPS2 | ENSP00000419449 | ENSP00000341885 | eukaryotic translation initiation factor 1; Necessary for scanning and involved in initiation site selection. Promotes the assembly of 48S ribosomal complexes at the authentic initiation codon of a conventional capped mRNA | ribosomal protein S2 | 0.822 |
EIF1 | RPS20 | ENSP00000419449 | ENSP00000429374 | eukaryotic translation initiation factor 1; Necessary for scanning and involved in initiation site selection. Promotes the assembly of 48S ribosomal complexes at the authentic initiation codon of a conventional capped mRNA | ribosomal protein S20 | 0.784 |
EIF1 | RPS23 | ENSP00000419449 | ENSP00000296674 | eukaryotic translation initiation factor 1; Necessary for scanning and involved in initiation site selection. Promotes the assembly of 48S ribosomal complexes at the authentic initiation codon of a conventional capped mRNA | ribosomal protein S23 | 0.813 |
EIF1 | RPS24 | ENSP00000419449 | ENSP00000414321 | eukaryotic translation initiation factor 1; Necessary for scanning and involved in initiation site selection. Promotes the assembly of 48S ribosomal complexes at the authentic initiation codon of a conventional capped mRNA | ribosomal protein S24; Required for processing of pre-rRNA and maturation of 40S ribosomal subunits | 0.762 |
EIF1 | RPS27A | ENSP00000419449 | ENSP00000272317 | eukaryotic translation initiation factor 1; Necessary for scanning and involved in initiation site selection. Promotes the assembly of 48S ribosomal complexes at the authentic initiation codon of a conventional capped mRNA | ribosomal protein S27a | 0.793 |
EIF1 | RPS28 | ENSP00000419449 | ENSP00000472469 | eukaryotic translation initiation factor 1; Necessary for scanning and involved in initiation site selection. Promotes the assembly of 48S ribosomal complexes at the authentic initiation codon of a conventional capped mRNA | ribosomal protein S28 | 0.814 |
EIF1 | RPS29 | ENSP00000419449 | ENSP00000379339 | eukaryotic translation initiation factor 1; Necessary for scanning and involved in initiation site selection. Promotes the assembly of 48S ribosomal complexes at the authentic initiation codon of a conventional capped mRNA | ribosomal protein S29 | 0.852 |
EIF1 | RPS3 | ENSP00000419449 | ENSP00000433821 | eukaryotic translation initiation factor 1; Necessary for scanning and involved in initiation site selection. Promotes the assembly of 48S ribosomal complexes at the authentic initiation codon of a conventional capped mRNA | ribosomal protein S3 | 0.869 |