node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
FAU | OAS1 | ENSP00000431822 | ENSP00000388001 | Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed | 2’-5’-oligoadenylate synthetase 1, 40/46kDa | 0.480 |
FAU | OAS2 | ENSP00000431822 | ENSP00000342278 | Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed | 2’-5’-oligoadenylate synthetase 2, 69/71kDa; Interferon-induced, dsRNA-activated antiviral enzyme which plays a critical role in cellular innate antiviral response. In addition, it may also play a role in other cellular processes such as apoptosis, cell growth, differentiation and gene regulation. Synthesizes higher oligomers of 2’-5’-oligoadenylates (2-5A) from ATP which then bind to the inactive monomeric form of ribonuclease L (RNase L) leading to its dimerization and subsequent activation. Activation of RNase L leads to degradation of cellular as well as viral RNA, resulting in the [...] | 0.480 |
FAU | UBC | ENSP00000431822 | ENSP00000344818 | Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed | ubiquitin C | 0.887 |
GOLGA7 | UBC | ENSP00000350378 | ENSP00000344818 | golgin A7; May be involved in protein transport from Golgi to cell surface. The ZDHHC9-GOLGA7 complex is a palmitoyltransferase specific for HRAS and NRAS | ubiquitin C | 0.923 |
GTF3C3 | UBC | ENSP00000263956 | ENSP00000344818 | general transcription factor IIIC, polypeptide 3, 102kDa; Involved in RNA polymerase III-mediated transcription. Integral, tightly associated component of the DNA-binding TFIIIC2 subcomplex that directly binds tRNA and virus-associated RNA promoters | ubiquitin C | 0.826 |
NDUFAB1 | SLC26A11 | ENSP00000007516 | ENSP00000355384 | NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa; Carrier of the growing fatty acid chain in fatty acid biosynthesis in mitochondria. Accessory and non-catalytic subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain (By similarity) | solute carrier family 26, member 11; Exhibits sodium-independent sulfate anion transporter activity that may cooperate with SLC26A2 to mediate DIDS-sensitive sulfate uptake into high endothelial venules endothelial cells (HEVEC) | 0.451 |
OAS1 | FAU | ENSP00000388001 | ENSP00000431822 | 2’-5’-oligoadenylate synthetase 1, 40/46kDa | Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed | 0.480 |
OAS1 | OAS2 | ENSP00000388001 | ENSP00000342278 | 2’-5’-oligoadenylate synthetase 1, 40/46kDa | 2’-5’-oligoadenylate synthetase 2, 69/71kDa; Interferon-induced, dsRNA-activated antiviral enzyme which plays a critical role in cellular innate antiviral response. In addition, it may also play a role in other cellular processes such as apoptosis, cell growth, differentiation and gene regulation. Synthesizes higher oligomers of 2’-5’-oligoadenylates (2-5A) from ATP which then bind to the inactive monomeric form of ribonuclease L (RNase L) leading to its dimerization and subsequent activation. Activation of RNase L leads to degradation of cellular as well as viral RNA, resulting in the [...] | 0.908 |
OAS2 | FAU | ENSP00000342278 | ENSP00000431822 | 2’-5’-oligoadenylate synthetase 2, 69/71kDa; Interferon-induced, dsRNA-activated antiviral enzyme which plays a critical role in cellular innate antiviral response. In addition, it may also play a role in other cellular processes such as apoptosis, cell growth, differentiation and gene regulation. Synthesizes higher oligomers of 2’-5’-oligoadenylates (2-5A) from ATP which then bind to the inactive monomeric form of ribonuclease L (RNase L) leading to its dimerization and subsequent activation. Activation of RNase L leads to degradation of cellular as well as viral RNA, resulting in the [...] | Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed | 0.480 |
OAS2 | OAS1 | ENSP00000342278 | ENSP00000388001 | 2’-5’-oligoadenylate synthetase 2, 69/71kDa; Interferon-induced, dsRNA-activated antiviral enzyme which plays a critical role in cellular innate antiviral response. In addition, it may also play a role in other cellular processes such as apoptosis, cell growth, differentiation and gene regulation. Synthesizes higher oligomers of 2’-5’-oligoadenylates (2-5A) from ATP which then bind to the inactive monomeric form of ribonuclease L (RNase L) leading to its dimerization and subsequent activation. Activation of RNase L leads to degradation of cellular as well as viral RNA, resulting in the [...] | 2’-5’-oligoadenylate synthetase 1, 40/46kDa | 0.908 |
OAS2 | UBC | ENSP00000342278 | ENSP00000344818 | 2’-5’-oligoadenylate synthetase 2, 69/71kDa; Interferon-induced, dsRNA-activated antiviral enzyme which plays a critical role in cellular innate antiviral response. In addition, it may also play a role in other cellular processes such as apoptosis, cell growth, differentiation and gene regulation. Synthesizes higher oligomers of 2’-5’-oligoadenylates (2-5A) from ATP which then bind to the inactive monomeric form of ribonuclease L (RNase L) leading to its dimerization and subsequent activation. Activation of RNase L leads to degradation of cellular as well as viral RNA, resulting in the [...] | ubiquitin C | 0.727 |
RAB4B | UBC | ENSP00000349560 | ENSP00000344818 | RAB4B, member RAS oncogene family; Protein transport. Probably involved in vesicular traffic (By similarity) | ubiquitin C | 0.497 |
SLC26A11 | NDUFAB1 | ENSP00000355384 | ENSP00000007516 | solute carrier family 26, member 11; Exhibits sodium-independent sulfate anion transporter activity that may cooperate with SLC26A2 to mediate DIDS-sensitive sulfate uptake into high endothelial venules endothelial cells (HEVEC) | NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa; Carrier of the growing fatty acid chain in fatty acid biosynthesis in mitochondria. Accessory and non-catalytic subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain (By similarity) | 0.451 |
SLC26A11 | UBC | ENSP00000355384 | ENSP00000344818 | solute carrier family 26, member 11; Exhibits sodium-independent sulfate anion transporter activity that may cooperate with SLC26A2 to mediate DIDS-sensitive sulfate uptake into high endothelial venules endothelial cells (HEVEC) | ubiquitin C | 0.663 |
UBC | FAU | ENSP00000344818 | ENSP00000431822 | ubiquitin C | Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed | 0.887 |
UBC | GOLGA7 | ENSP00000344818 | ENSP00000350378 | ubiquitin C | golgin A7; May be involved in protein transport from Golgi to cell surface. The ZDHHC9-GOLGA7 complex is a palmitoyltransferase specific for HRAS and NRAS | 0.923 |
UBC | GTF3C3 | ENSP00000344818 | ENSP00000263956 | ubiquitin C | general transcription factor IIIC, polypeptide 3, 102kDa; Involved in RNA polymerase III-mediated transcription. Integral, tightly associated component of the DNA-binding TFIIIC2 subcomplex that directly binds tRNA and virus-associated RNA promoters | 0.826 |
UBC | OAS2 | ENSP00000344818 | ENSP00000342278 | ubiquitin C | 2’-5’-oligoadenylate synthetase 2, 69/71kDa; Interferon-induced, dsRNA-activated antiviral enzyme which plays a critical role in cellular innate antiviral response. In addition, it may also play a role in other cellular processes such as apoptosis, cell growth, differentiation and gene regulation. Synthesizes higher oligomers of 2’-5’-oligoadenylates (2-5A) from ATP which then bind to the inactive monomeric form of ribonuclease L (RNase L) leading to its dimerization and subsequent activation. Activation of RNase L leads to degradation of cellular as well as viral RNA, resulting in the [...] | 0.727 |
UBC | RAB4B | ENSP00000344818 | ENSP00000349560 | ubiquitin C | RAB4B, member RAS oncogene family; Protein transport. Probably involved in vesicular traffic (By similarity) | 0.497 |
UBC | SLC26A11 | ENSP00000344818 | ENSP00000355384 | ubiquitin C | solute carrier family 26, member 11; Exhibits sodium-independent sulfate anion transporter activity that may cooperate with SLC26A2 to mediate DIDS-sensitive sulfate uptake into high endothelial venules endothelial cells (HEVEC) | 0.663 |