node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CNST | GGA1 | ENSP00000355470 | ENSP00000341344 | consortin, connexin sorting protein; Required for targeting of connexins to the plasma membrane | golgi-associated, gamma adaptin ear containing, ARF binding protein 1 | 0.441 |
CNST | GGA2 | ENSP00000355470 | ENSP00000311962 | consortin, connexin sorting protein; Required for targeting of connexins to the plasma membrane | golgi-associated, gamma adaptin ear containing, ARF binding protein 2; Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates the ARF- dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (AC-LL) motif | 0.534 |
CNST | GJA1 | ENSP00000355470 | ENSP00000282561 | consortin, connexin sorting protein; Required for targeting of connexins to the plasma membrane | gap junction protein, alpha 1, 43kDa; Gap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph. Negative regulator of bladder functional capacity- acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural s [...] | 0.689 |
CNST | GJB1 | ENSP00000355470 | ENSP00000354900 | consortin, connexin sorting protein; Required for targeting of connexins to the plasma membrane | gap junction protein, beta 1, 32kDa; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell (By similarity) | 0.702 |
CNST | GJB2 | ENSP00000355470 | ENSP00000372295 | consortin, connexin sorting protein; Required for targeting of connexins to the plasma membrane | gap junction protein, beta 2, 26kDa; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell (By similarity) | 0.850 |
CNST | GJB3 | ENSP00000355470 | ENSP00000362460 | consortin, connexin sorting protein; Required for targeting of connexins to the plasma membrane | gap junction protein, beta 3, 31kDa; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell | 0.567 |
CNST | GJB6 | ENSP00000355470 | ENSP00000241124 | consortin, connexin sorting protein; Required for targeting of connexins to the plasma membrane | gap junction protein, beta 6, 30kDa; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell | 0.886 |
CNST | GJC1 | ENSP00000355470 | ENSP00000333193 | consortin, connexin sorting protein; Required for targeting of connexins to the plasma membrane | gap junction protein, gamma 1, 45kDa; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell (By similarity) | 0.747 |
CNST | PPP1CA | ENSP00000355470 | ENSP00000326031 | consortin, connexin sorting protein; Required for targeting of connexins to the plasma membrane | protein phosphatase 1, catalytic subunit, alpha isozyme; Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase 1 (PP1) is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Involved in regulation of ionic conductances and long-term synaptic plasticity. May play an important role in dephosphorylating substrates such as the postsynaptic density-associated Ca(2+)/calmodulin dependent p [...] | 0.446 |
CNST | PPP1CC | ENSP00000355470 | ENSP00000335084 | consortin, connexin sorting protein; Required for targeting of connexins to the plasma membrane | protein phosphatase 1, catalytic subunit, gamma isozyme; Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase 1 (PP1) is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Dephosphorylates RPS6KB1. Involved in regulation of ionic conductances and long-term synaptic plasticity. May play an important role in dephosphorylating substrates such as the postsynaptic density- associated Ca [...] | 0.425 |
CNST | ROPN1 | ENSP00000355470 | ENSP00000184183 | consortin, connexin sorting protein; Required for targeting of connexins to the plasma membrane | rhophilin associated tail protein 1 | 0.504 |
GGA1 | CNST | ENSP00000341344 | ENSP00000355470 | golgi-associated, gamma adaptin ear containing, ARF binding protein 1 | consortin, connexin sorting protein; Required for targeting of connexins to the plasma membrane | 0.441 |
GGA1 | GGA2 | ENSP00000341344 | ENSP00000311962 | golgi-associated, gamma adaptin ear containing, ARF binding protein 1 | golgi-associated, gamma adaptin ear containing, ARF binding protein 2; Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates the ARF- dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (AC-LL) motif | 0.736 |
GGA1 | GJC1 | ENSP00000341344 | ENSP00000333193 | golgi-associated, gamma adaptin ear containing, ARF binding protein 1 | gap junction protein, gamma 1, 45kDa; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell (By similarity) | 0.404 |
GGA2 | CNST | ENSP00000311962 | ENSP00000355470 | golgi-associated, gamma adaptin ear containing, ARF binding protein 2; Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates the ARF- dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (AC-LL) motif | consortin, connexin sorting protein; Required for targeting of connexins to the plasma membrane | 0.534 |
GGA2 | GGA1 | ENSP00000311962 | ENSP00000341344 | golgi-associated, gamma adaptin ear containing, ARF binding protein 2; Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates the ARF- dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (AC-LL) motif | golgi-associated, gamma adaptin ear containing, ARF binding protein 1 | 0.736 |
GGA2 | GJB2 | ENSP00000311962 | ENSP00000372295 | golgi-associated, gamma adaptin ear containing, ARF binding protein 2; Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates the ARF- dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (AC-LL) motif | gap junction protein, beta 2, 26kDa; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell (By similarity) | 0.405 |
GGA2 | GJC1 | ENSP00000311962 | ENSP00000333193 | golgi-associated, gamma adaptin ear containing, ARF binding protein 2; Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates the ARF- dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (AC-LL) motif | gap junction protein, gamma 1, 45kDa; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell (By similarity) | 0.515 |
GJA1 | CNST | ENSP00000282561 | ENSP00000355470 | gap junction protein, alpha 1, 43kDa; Gap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph. Negative regulator of bladder functional capacity- acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural s [...] | consortin, connexin sorting protein; Required for targeting of connexins to the plasma membrane | 0.689 |
GJA1 | GJB1 | ENSP00000282561 | ENSP00000354900 | gap junction protein, alpha 1, 43kDa; Gap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph. Negative regulator of bladder functional capacity- acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural s [...] | gap junction protein, beta 1, 32kDa; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell (By similarity) | 0.757 |