11 items (Homo sapiens) - STRING network view

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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protein of unknown 3D structure

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Your Input:
	MOB1B	MOB kinase activator 1B; Activator of LATS1/2 in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Phosphorylation of YAP1 by LATS1/2 inhibits its translocation into the nucleus to regulate cellu [...] (216 aa)
	MINOS1	mitochondrial inner membrane organizing system 1; May play a role in mitochondrial architecture (By similarity) (78 aa)
	MOB2	MOB kinase activator 2; Stimulates the autophosphorylation and kinase activity of STK38 and STK38L (268 aa)
	NADK	NAD kinase (591 aa)
	UBC	ubiquitin C (685 aa)
	IBA57	IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae); Required for normal heme biosynthesis (By similarity) (356 aa)
	DDX43	DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 (648 aa)
	ISCA1	iron-sulfur cluster assembly 1 homolog (S. cerevisiae); Involved in the assembly of mitochondrial iron-sulfur proteins. Probably involved in the binding of an intermediate of Fe/S cluster assembly (129 aa)
	DDX53	DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 (631 aa)
	MOB1A	MOB kinase activator 1A; Activator of LATS1/2 in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Phosphorylation of YAP1 by LATS1/2 inhibits its translocation into the nucleus to regulate cellu [...] (216 aa)
	ISCA2	iron-sulfur cluster assembly 2 homolog (S. cerevisiae); Involved in the assembly of mitochondrial iron-sulfur proteins. Probably involved in the binding of an intermediate of Fe/S cluster assembly (By similarity) (154 aa)

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
IBA57	ISCA1	ENSP00000355672	ENSP00000365159	IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae); Required for normal heme biosynthesis (By similarity)	iron-sulfur cluster assembly 1 homolog (S. cerevisiae); Involved in the assembly of mitochondrial iron-sulfur proteins. Probably involved in the binding of an intermediate of Fe/S cluster assembly	0.986
IBA57	ISCA2	ENSP00000355672	ENSP00000452007	IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae); Required for normal heme biosynthesis (By similarity)	iron-sulfur cluster assembly 2 homolog (S. cerevisiae); Involved in the assembly of mitochondrial iron-sulfur proteins. Probably involved in the binding of an intermediate of Fe/S cluster assembly (By similarity)	0.987
IBA57	MINOS1	ENSP00000355672	ENSP00000325562	IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae); Required for normal heme biosynthesis (By similarity)	mitochondrial inner membrane organizing system 1; May play a role in mitochondrial architecture (By similarity)	0.512
IBA57	UBC	ENSP00000355672	ENSP00000344818	IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae); Required for normal heme biosynthesis (By similarity)	ubiquitin C	0.483
ISCA1	IBA57	ENSP00000365159	ENSP00000355672	iron-sulfur cluster assembly 1 homolog (S. cerevisiae); Involved in the assembly of mitochondrial iron-sulfur proteins. Probably involved in the binding of an intermediate of Fe/S cluster assembly	IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae); Required for normal heme biosynthesis (By similarity)	0.986
ISCA1	ISCA2	ENSP00000365159	ENSP00000452007	iron-sulfur cluster assembly 1 homolog (S. cerevisiae); Involved in the assembly of mitochondrial iron-sulfur proteins. Probably involved in the binding of an intermediate of Fe/S cluster assembly	iron-sulfur cluster assembly 2 homolog (S. cerevisiae); Involved in the assembly of mitochondrial iron-sulfur proteins. Probably involved in the binding of an intermediate of Fe/S cluster assembly (By similarity)	0.413
ISCA2	IBA57	ENSP00000452007	ENSP00000355672	iron-sulfur cluster assembly 2 homolog (S. cerevisiae); Involved in the assembly of mitochondrial iron-sulfur proteins. Probably involved in the binding of an intermediate of Fe/S cluster assembly (By similarity)	IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae); Required for normal heme biosynthesis (By similarity)	0.987
ISCA2	ISCA1	ENSP00000452007	ENSP00000365159	iron-sulfur cluster assembly 2 homolog (S. cerevisiae); Involved in the assembly of mitochondrial iron-sulfur proteins. Probably involved in the binding of an intermediate of Fe/S cluster assembly (By similarity)	iron-sulfur cluster assembly 1 homolog (S. cerevisiae); Involved in the assembly of mitochondrial iron-sulfur proteins. Probably involved in the binding of an intermediate of Fe/S cluster assembly	0.413
MINOS1	IBA57	ENSP00000325562	ENSP00000355672	mitochondrial inner membrane organizing system 1; May play a role in mitochondrial architecture (By similarity)	IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae); Required for normal heme biosynthesis (By similarity)	0.512
MOB1A	MOB1B	ENSP00000379364	ENSP00000310189	MOB kinase activator 1A; Activator of LATS1/2 in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Phosphorylation of YAP1 by LATS1/2 inhibits its translocation into the nucleus to regulate cellu [...]	MOB kinase activator 1B; Activator of LATS1/2 in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Phosphorylation of YAP1 by LATS1/2 inhibits its translocation into the nucleus to regulate cellu [...]	0.960
MOB1A	UBC	ENSP00000379364	ENSP00000344818	MOB kinase activator 1A; Activator of LATS1/2 in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Phosphorylation of YAP1 by LATS1/2 inhibits its translocation into the nucleus to regulate cellu [...]	ubiquitin C	0.795
MOB1B	MOB1A	ENSP00000310189	ENSP00000379364	MOB kinase activator 1B; Activator of LATS1/2 in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Phosphorylation of YAP1 by LATS1/2 inhibits its translocation into the nucleus to regulate cellu [...]	MOB kinase activator 1A; Activator of LATS1/2 in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Phosphorylation of YAP1 by LATS1/2 inhibits its translocation into the nucleus to regulate cellu [...]	0.960
MOB1B	UBC	ENSP00000310189	ENSP00000344818	MOB kinase activator 1B; Activator of LATS1/2 in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Phosphorylation of YAP1 by LATS1/2 inhibits its translocation into the nucleus to regulate cellu [...]	ubiquitin C	0.853
NADK	UBC	ENSP00000340925	ENSP00000344818	NAD kinase	ubiquitin C	0.469
UBC	IBA57	ENSP00000344818	ENSP00000355672	ubiquitin C	IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae); Required for normal heme biosynthesis (By similarity)	0.483
UBC	MOB1A	ENSP00000344818	ENSP00000379364	ubiquitin C	MOB kinase activator 1A; Activator of LATS1/2 in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Phosphorylation of YAP1 by LATS1/2 inhibits its translocation into the nucleus to regulate cellu [...]	0.795
UBC	MOB1B	ENSP00000344818	ENSP00000310189	ubiquitin C	MOB kinase activator 1B; Activator of LATS1/2 in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Phosphorylation of YAP1 by LATS1/2 inhibits its translocation into the nucleus to regulate cellu [...]	0.853
UBC	NADK	ENSP00000344818	ENSP00000340925	ubiquitin C	NAD kinase	0.469

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