Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small nodes:
protein of unknown 3D structure
protein of unknown 3D structure
large nodes:
some 3D structure is known or predicted
some 3D structure is known or predicted
Node Color
colored nodes:
query proteins and first shell of interactors
query proteins and first shell of interactors
white nodes:
second shell of interactors
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Your Input:
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 | MRPL28 | mitochondrial ribosomal protein L28 (256 aa) | ||
 | MRPL51 | mitochondrial ribosomal protein L51 (128 aa) | ||
 | MRPS2 | mitochondrial ribosomal protein S2 (296 aa) | ||
 | MRPS18B | mitochondrial ribosomal protein S18B (258 aa) | ||
 | MRPL15 | mitochondrial ribosomal protein L15 (296 aa) | ||
 | MRPS27 | mitochondrial ribosomal protein S27 (414 aa) | ||
 | MRPS17 | mitochondrial ribosomal protein S17 (130 aa) | ||
 | MRPS18C | mitochondrial ribosomal protein S18C (142 aa) | ||
 | MRPL33 | mitochondrial ribosomal protein L33 (65 aa) | ||
 | MRPL13 | mitochondrial ribosomal protein L13 (178 aa) | ||
 | MRPL48 | mitochondrial ribosomal protein L48 (212 aa) | ||
 | MRPL11 | mitochondrial ribosomal protein L11 (192 aa) | ||
 | MRP63 | mitochondrial ribosomal protein 63 (102 aa) | ||
 | MRPL46 | mitochondrial ribosomal protein L46 (279 aa) | ||
 | MRPS21 | mitochondrial ribosomal protein S21 (87 aa) | ||
 | AURKAIP1 | aurora kinase A interacting protein 1; May act as a negative regulator of Aurora-A kinase, by down-regulation through proteasome-dependent degradation (199 aa) | ||
 | GADD45GIP1 | growth arrest and DNA-damage-inducible, gamma interacting protein 1; Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis (222 aa) | ||
 | MRPL35 | mitochondrial ribosomal protein L35 (188 aa) | ||
 | MTRF1L | mitochondrial translational release factor 1-like; Mitochondrial peptide chain release factor that directs the termination of translation in response to the peptide chain termination codons UAA and UAG (380 aa) | ||
 | MRPL9 | mitochondrial ribosomal protein L9 (267 aa) | ||
 | MRPL50 | mitochondrial ribosomal protein L50 (158 aa) | ||
 | MRPL36 | mitochondrial ribosomal protein L36; Component of the large subunit of the mitochondrial ribosome (Potential) (103 aa) | ||
 | MRPS34 | mitochondrial ribosomal protein S34 (218 aa) | ||
 | MRPS6 | mitochondrial ribosomal protein S6 (125 aa) | ||
 | MRPL47 | mitochondrial ribosomal protein L47 (250 aa) | ||
 | MRPS14 | mitochondrial ribosomal protein S14 (128 aa) | ||
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
Other names: H. sapiens, Homo, Homo sapiens, human, man
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