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RABAC1 | Rab acceptor 1 (prenylated); General Rab protein regulator required for vesicle formation from the Golgi complex. May control vesicle docking and fusion by mediating the action of Rab GTPases to the SNARE complexes. In addition it inhibits the removal of Rab GTPases from the membrane by GDI (By similarity) (185 aa) | |||
GNB3 | guanine nucleotide binding protein (G protein), beta polypeptide 3; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction (340 aa) | |||
GNAT1 | guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Transducin is an amplifier and one of the transducers of a visual impulse that performs the coupling between rhodopsin and cGMP-phosphodiesterase (350 aa) | |||
GNB4 | guanine nucleotide binding protein (G protein), beta polypeptide 4; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction (340 aa) | |||
GNAT2 | guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Transducin is an amplifier and one of the transducers of a visual impulse that performs the coupling between rhodopsin and cGMP-phosphodiesterase (354 aa) | |||
GNAO1 | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(o) protein function is not clear. Stimulated by RGS14 (354 aa) | |||
SUCO | SUN domain containing ossification factor; Required for bone modeling during late embryogenesis. Regulates type I collagen synthesis in osteoblasts during their postnatal maturation (By similarity) (1254 aa) | |||
PWP2 | PWP2 periodic tryptophan protein homolog (yeast) (919 aa) | |||
GNB2 | guanine nucleotide binding protein (G protein), beta polypeptide 2; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction (340 aa) | |||
GNAI2 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase- they inhibit the cyclase in response to beta-adrenergic stimuli. May play a role in cell division (355 aa) | |||
GPR89A | G protein-coupled receptor 89A (455 aa) | |||
TBC1D22A | TBC1 domain family, member 22A (517 aa) | |||
GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 (354 aa) | |||
UBC | ubiquitin C (685 aa) | |||
XPR1 | xenotropic and polytropic retrovirus receptor 1; May function in G-protein coupled signal transduction (By similarity). Potential receptor for xenotropic and polytropic murine leukemia retroviruses (696 aa) | |||
GPR89B | G protein-coupled receptor 89B (455 aa) | |||
GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. G(k) is the stimulatory G protein of receptor- regulated K(+) channels. The active GTP-bound form prevents the association of RGS14 with centrosomes and is required for the translocation of RGS14 from the cytoplasm to the plasma membrane. May play a role in cell division (354 aa) | |||
TBC1D22B | TBC1 domain family, member 22B; May act as a GTPase-activating protein for Rab family protein(s) (By similarity) (505 aa) | |||
GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction (340 aa) | |||
GNAT3 | guanine nucleotide binding protein, alpha transducing 3; Guanine nucleotide-binding protein (G protein) alpha subunit playing a prominent role in bitter and sweet taste transduction as well as in umami (monosodium glutamate, monopotassium glutamate, and inosine monophosphate) taste transduction. Transduction by this alpha subunit involves coupling of specific cell-surface receptors with a cGMP-phosphodiesterase; Activation of phosphodiesterase lowers intracellular levels of cAMP and cGMP which may open a cyclic nucleotide-suppressible cation channel leading to influx of calcium, ultima [...] (354 aa) | |||
ELAVL1 | ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R); Involved in 3’-UTR ARE-mediated MYC stabilization. Binds avidly to the AU-rich element in FOS and IL3/interleukin-3 mRNAs. In the case of the FOS AU-rich element, HUR binds to a core element of 27 nucleotides that contain AUUUA, AUUUUA and AUUUUUA motifs. Binds preferentially to the 5’-UUUU[AG]UUU-3’ motif in vitro (326 aa) | |||
MCC | mutated in colorectal cancers; Candidate for the putative colorectal tumor suppressor gene located at 5q21. Suppresses cell proliferation and the Wnt/b- catenin pathway in colorectal cancer cells. Inhibits DNA binding of b-catenin/TCF/LEF transcription factors. Involved in cell migration independently of RAC1, CDC42 and p21-activated kinase (PAK) activation (1019 aa) | |||
GPR89C | G protein-coupled receptor 89C (320 aa) | |||
ENSG00000248354 | Uncharacterized protein (205 aa) | |||
KIAA1432 | KIAA1432 (1423 aa) |