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PIGV | phosphatidylinositol glycan anchor biosynthesis, class V; Alpha-1,6-mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the second mannose to the glycosylphosphatidylinositol during GPI precursor assembly (493 aa) | |||
PIGB | phosphatidylinositol glycan anchor biosynthesis, class B; Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the third alpha-1,2-mannose to Man2-GlcN-acyl-PI during GPI precursor assembly (554 aa) | |||
PIGU | phosphatidylinositol glycan anchor biosynthesis, class U; Component of the GPI transamidase complex. May be involved in the recognition of either the GPI attachment signal or the lipid portion of GPI (435 aa) | |||
ALG5 | asparagine-linked glycosylation 5, dolichyl-phosphate beta-glucosyltransferase homolog (S. cerevisiae) (324 aa) | |||
PIGC | phosphatidylinositol glycan anchor biosynthesis, class C; Part of the complex catalyzing the transfer of N- acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis (297 aa) | |||
PIGT | phosphatidylinositol glycan anchor biosynthesis, class T (578 aa) | |||
PIGX | phosphatidylinositol glycan anchor biosynthesis, class X; Essential component of glycosylphosphatidylinositol- mannosyltransferase 1 which transfers the first of the 4 mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis. Probably acts by stabilizing the mannosyltransferase PIGM (By similarity) (276 aa) | |||
ARV1 | ARV1 homolog (S. cerevisiae) (271 aa) | |||
B3GNTL1 | UDP-GlcNAc-betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1; Putative glycosyltransferase (Potential) (361 aa) | |||
DPM2 | dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit; Regulates the biosynthesis of dolichol phosphate- mannose. Essential for the ER localization and stable expression of DPM1 (84 aa) | |||
PIGW | phosphatidylinositol glycan anchor biosynthesis, class W; Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI- anchor. Acetylation during GPI-anchor biosynthesis is not essential for the subsequent mannosylation and is usually removed soon after the attachment of GPIs to proteins (By similarity) (504 aa) | |||
STARD7 | StAR-related lipid transfer (START) domain containing 7 (370 aa) | |||
PIGN | phosphatidylinositol glycan anchor biosynthesis, class N; Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor (By similarity) (931 aa) | |||
CNDP1 | carnosine dipeptidase 1 (metallopeptidase M20 family) (507 aa) | |||
PIGM | phosphatidylinositol glycan anchor biosynthesis, class M; Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN-acyl-PI during GPI precursor assembly (423 aa) | |||
DPM3 | dolichyl-phosphate mannosyltransferase polypeptide 3; Stabilizer subunit of the dolichol-phosphate-mannose synthase complex (122 aa) | |||
ALG14 | asparagine-linked glycosylation 14 homolog (S. cerevisiae); May be involved in protein N-glycosylation. May play a role in the second step of the dolichol-linked oligosaccharide pathway. May anchor the catalytic subunit ALG13 to the ER (216 aa) | |||
ALG6 | asparagine-linked glycosylation 6, alpha-1,3-glucosyltransferase homolog (S. cerevisiae); Adds the first glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Man(9)GlcNAc(2)-PP-Dol (507 aa) | |||
DPM1 | dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit; Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O- mannosylation of proteins (260 aa) | |||
ALG3 | asparagine-linked glycosylation 3, alpha-1,3- mannosyltransferase homolog (S. cerevisiae); Adds the first Dol-P-Man derived mannose in an alpha-1,3 linkage to Man5GlcNAc2-PP-Dol (438 aa) | |||
PIGZ | phosphatidylinositol glycan anchor biosynthesis, class Z; Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers a fourth mannose to some trimannosyl-GPIs during GPI precursor assembly. The presence of a fourth mannose in GPI is facultative and only scarcely detected, suggesting that it only exists in some tissues (579 aa) | |||
PIGP | phosphatidylinositol glycan anchor biosynthesis, class P (158 aa) |