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SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2; Low-affinity, high capacity permease involved in the transport of the cationic amino acids (arginine, lysine and ornithine). Plays a regulatory role in classical or alternative activation of macrophages (By similarity) (698 aa) | |||
SLC7A9 | solute carrier family 7 (glycoprotein-associated amino acid transporter light chain, bo,+ system), member 9; Involved in the high-affinity, sodium-independent transport of cystine and neutral and dibasic amino acids (system b(0,+)-like activity). Thought to be responsible for the high- affinity reabsorption of cystine in the kidney tubule (487 aa) | |||
SLC7A6 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 6; Involved in the sodium-independent uptake of dibasic amino acids and sodium-dependent uptake of some neutral amino acids. Requires coexpression with SLC3A2/4F2hc to mediate the uptake of arginine, leucine and glutamine. Also acts as an arginine/glutamine exchanger, following an antiport mechanism for amino acid transport, influencing arginine release in exchange for extracellular amino acids. Plays a role in nitric oxide synthesis in human umbilical vein endothelial cells (HUVECs) via transport of L-arg [...] (515 aa) | |||
SLC7A14 | solute carrier family 7 (orphan transporter), member 14 (771 aa) | |||
SLC7A10 | solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10; Sodium-independent, high affinity transport of small neutral D- and L-amino acids. May play a role in the modulation of glutamatergic transmission through mobilization of D-serine at the glutamatergic synapse (523 aa) | |||
SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5; Sodium-independent, high-affinity transport of large neutral amino acids such as phenylalanine, tyrosine, leucine, arginine and tryptophan, when associated with SLC3A2/4F2hc. Involved in cellular amino acid uptake. Acts as an amino acid exchanger. Involved in the transport of L-DOPA across the blood- brain barrier, and that of thyroid hormones triiodothyronine (T3) and thyroxine (T4) across the cell membrane in tissues such as placenta. Plays a role in neuronal cell proliferation (neurogenesis) in brain. [...] (507 aa) | |||
SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporters), member 2; Electrically silent transporter system. Mediates sodium and chloride reabsorption. Plays a vital role in the regulation of ionic balance and cell volume (1212 aa) | |||
SLC12A7 | solute carrier family 12 (potassium/chloride transporters), member 7; Mediates electroneutral potassium-chloride cotransport when activated by cell swelling. May mediate K(+) uptake into Deiters’ cells in the cochlea and contribute to K(+) recycling in the inner ear. Important for the survival of cochlear outer and inner hair cells and the maintenance of the organ of Corti. May be required for basolateral Cl(-) extrusion in the kidney and contribute to renal acidification (By similarity) (1083 aa) | |||
SLC12A9 | solute carrier family 12 (potassium/chloride transporters), member 9 (914 aa) | |||
SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11; Sodium-independent, high-affinity exchange of anionic amino acids with high specificity for anionic form of cystine and glutamate (501 aa) | |||
SLC7A13 | solute carrier family 7 (anionic amino acid transporter), member 13; Mediates the transport L-aspartate and L-glutamate in a sodium-independent manner (By similarity) (470 aa) | |||
SLC7A3 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 3; Mediates the uptake of the cationic amino acids arginine, lysine and ornithine in a sodium-independent manner (619 aa) | |||
RACGAP1 | Rac GTPase activating protein 1; Component of the centralspindlin complex that serves as a microtubule-dependent and Rho-mediated signaling required for the myosin contractile ring formation during the cell cycle cytokinesis. Plays key roles in controlling cell growth and differentiation of hematopoietic cells through mechanisms other than regulating Rac GTPase activity. Also involved in the regulation of growth-related processes in adipocytes and myoblasts. May be involved in regulating spermatogenesis and in the RACGAP1 pathway in neuronal proliferation. Shows strong GAP (GTPase acti [...] (632 aa) | |||
SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8; Sodium-independent, high-affinity transport of small and large neutral amino acids such as alanine, serine, threonine, cysteine, phenylalanine, tyrosine, leucine, arginine and tryptophan, when associated with SLC3A2/4F2hc. Acts as an amino acid exchanger. Has higher affinity for L-phenylalanine than LAT1 but lower affinity for glutamine and serine. L-alanine is transported at physiological concentrations. Plays a role in basolateral (re)absorption of neutral amino acids. Involved in the uptake of methylme [...] (535 aa) | |||
UBC | ubiquitin C (685 aa) | |||
SLC16A10 | solute carrier family 16, member 10 (aromatic amino acid transporter); Sodium-independent transporter that mediates the update of aromatic acid. Can function as a net efflux pathway for aromatic amino acids in the basosolateral epithelial cells (By similarity) (515 aa) | |||
GPN2 | GPN-loop GTPase 2 (310 aa) | |||
SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1; High-affinity, low capacity permease involved in the transport of the cationic amino acids (arginine, lysine and ornithine) in non-hepatic tissues. May also function as an ecotropic retroviral leukemia receptor (629 aa) | |||
SLC12A1 | solute carrier family 12 (sodium/potassium/chloride transporters), member 1; Electrically silent transporter system. Mediates sodium and chloride reabsorption. Plays a vital role in the regulation of ionic balance and cell volume (1099 aa) | |||
SLC7A4 | solute carrier family 7 (orphan transporter), member 4; Involved in the transport of the cationic amino acids (arginine, lysine and ornithine) (635 aa) | |||
SLC12A8 | solute carrier family 12 (potassium/chloride transporters), member 8 (714 aa) | |||
SLC12A5 | solute carrier family 12 (potassium/chloride transporter), member 5; Mediates electroneutral potassium-chloride cotransport in mature neurons. Transport occurs under isotonic conditions, but is activated 20-fold by cell swelling. Important for Cl(-) homeostasis in neurons (1139 aa) | |||
SLC12A4 | solute carrier family 12 (potassium/chloride transporters), member 4 (1087 aa) | |||
SLC12A3 | solute carrier family 12 (sodium/chloride transporters), member 3; Key mediator of sodium and chloride reabsorption in this nephron segment, accounting for a significant fraction of renal sodium reabsorption (1030 aa) | |||
SLC12A6 | solute carrier family 12 (potassium/chloride transporters), member 6 (1141 aa) | |||
ENSG00000268864 | Uncharacterized protein (142 aa) |