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STRINGSTRING
SAR1B SAR1B DHCR24 DHCR24 RNF220 RNF220 PCYT1A PCYT1A AGPS AGPS HIBCH HIBCH C12orf10 C12orf10 D2HGDH D2HGDH LDHD LDHD ZC4H2 ZC4H2 ACOT11 ACOT11
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
AGPSalkylglycerone phosphate synthase; Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids (By similarity) (658 aa)
C12orf10chromosome 12 open reading frame 10 (376 aa)
PCYT1Aphosphate cytidylyltransferase 1, choline, alpha; Controls phosphatidylcholine synthesis (367 aa)
LDHDlactate dehydrogenase D (507 aa)
D2HGDHD-2-hydroxyglutarate dehydrogenase; Catalyzes the oxidation of D-2-hydroxyglutarate to alpha-ketoglutarate (521 aa)
RNF220ring finger protein 220; E3 ubiquitin-protein ligase that promotes the ubiquitination and proteasomal degradation of SIN3B (By similarity) (566 aa)
HIBCH3-hydroxyisobutyryl-CoA hydrolase; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite. Has high activity toward isobutyryl-CoA. Could be an isobutyryl-CoA dehydrogenase that functions in valine catabolism. Also hydrolyzes 3-hydroxypropanoyl-CoA (386 aa)
DHCR2424-dehydrocholesterol reductase; Catalyzes the reduction of the delta-24 double bond of sterol intermediates. Protects cells from oxidative stress by reducing caspase 3 activity during apoptosis induced by oxidative stress. Also protects against amyloid-beta peptide-induced apoptosis (516 aa)
ACOT11acyl-CoA thioesterase 11; Has acyl-CoA thioesterase activity towards medium (C12) and long-chain (C18) fatty acyl-CoA substrates (607 aa)
ZC4H2zinc finger, C4H2 domain containing (224 aa)
SAR1BSAR1 homolog B (S. cerevisiae); Involved in transport from the endoplasmic reticulum to the Golgi apparatus. Activated by the guanine nucleotide exchange factor PREB. Involved in the selection of the protein cargo and the assembly of the COPII coat complex (198 aa)
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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