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TSPO TSPO RPL7A RPL7A RPL21 RPL21 RPL23 RPL23 RPL14 RPL14 RPL7 RPL7 RPS28 RPS28 RPL15 RPL15 RPL37A RPL37A RPS8 RPS8 RPL31 RPL31 RPL9 RPL9 RPS3A RPS3A RPL10A RPL10A RPL23A RPL23A RPS19 RPS19 RPL11 RPL11 RPS21 RPS21 SLC25A4 SLC25A4 SLC25A5 SLC25A5 SLC25A24 SLC25A24 CIAO1 CIAO1 MMS19 MMS19 ERCC2 ERCC2 FAM96B FAM96B SLC25A31 SLC25A31
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
SLC25A31solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31; Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane. May serve to mediate energy generating and energy consuming processes in the distal flagellum, possibly as a nucleotide shuttle between flagellar glycolysis, protein phosphorylation and mechanisms of motility (315 aa)
SLC25A4solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4; Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane (298 aa)
RPL15ribosomal protein L15 (204 aa)
TSPOtranslocator protein (18kDa); Responsible for the manifestation of peripheral-type benzodiazepine recognition sites and is most likely to comprise binding domains for benzodiazepines and isoquinoline carboxamides. May play a role in the transport of porphyrins and heme. Plays a role in the transport of cholesterol across mitochondrial membranes in steroidogenic cells (By similarity) (169 aa)
RPL7ribosomal protein L7; Binds to G-rich structures in 28S rRNA and in mRNAs. Plays a regulatory role in the translation apparatus; inhibits cell-free translation of mRNAs (248 aa)
RPL14ribosomal protein L14 (215 aa)
RPS21ribosomal protein S21 (83 aa)
RPL9ribosomal protein L9 (192 aa)
RPL21ribosomal protein L21 (160 aa)
RPS3Aribosomal protein S3A; May play a role during erythropoiesis through regulation of transcription factor DDIT3 (By similarity) (264 aa)
MMS19MMS19 nucleotide excision repair homolog (S. cerevisiae) (1030 aa)
SLC25A5solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5; Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation (298 aa)
RPL7Aribosomal protein L7a (266 aa)
RPL10Aribosomal protein L10a (217 aa)
RPL11ribosomal protein L11; Binds to 5S ribosomal RNA (By similarity). Required for rRNA maturation and formation of the 60S ribosomal subunits. Promotes nucleolar location of PML (By similarity) (178 aa)
ERCC2excision repair cross-complementing rodent repair deficiency, complementation group 2; ATP-dependent 5’-3’ DNA helicase, component of the core- TFIIH basal transcription factor. Involved in nucleotide excision repair (NER) of DNA by opening DNA around the damage, and in RNA transcription by RNA polymerase II by anchoring the CDK-activating kinase (CAK) complex, composed of CDK7, cyclin H and MAT1, to the core-TFIIH complex. Involved in the regulation of vitamin-D receptor activity. As part of the mitotic spindle-associated MMXD complex it plays a role in chromosome segregation. Might h [...] (760 aa)
RPL23ribosomal protein L23 (140 aa)
RPS8ribosomal protein S8 (208 aa)
RPL31ribosomal protein L31 (128 aa)
FAM96Bfamily with sequence similarity 96, member B; Component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. As part of the mitotic spindle-associated MMXD complex it plays a role in chromosome segregation, probably by facilitating iron-sulfur cluster assembly into ERCC2/XPD (163 aa)
RPL23Aribosomal protein L23a; This protein binds to a specific region on the 26S rRNA (By similarity) (156 aa)
RPL37Aribosomal protein L37a (92 aa)
CIAO1cytosolic iron-sulfur protein assembly 1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to specifically modulate the transactivation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation (339 aa)
SLC25A24solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24; Calcium-dependent mitochondrial solute carrier. Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane. May act as a ATP-Mg/Pi exchanger that mediates the transport of Mg-ATP in exchange for phosphate, catalyzing the net uptake or efflux of adenine nucleotides into or from the mitochondria (477 aa)
RPS19ribosomal protein S19; Required for pre-rRNA processing and maturation of 40S ribosomal subunits (145 aa)
RPS28ribosomal protein S28 (69 aa)
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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