node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
B4GALT5 | GCNT1 | ENSP00000360776 | ENSP00000365920 | UDP-Gal-betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5; Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids | glucosaminyl (N-acetyl) transferase 1, core 2; Forms critical branches in O-glycans | 0.908 |
B4GALT5 | MUC1 | ENSP00000360776 | ENSP00000357380 | UDP-Gal-betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5; Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids | mucin 1, cell surface associated | 0.900 |
B4GALT5 | MUC12 | ENSP00000360776 | ENSP00000441929 | UDP-Gal-betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5; Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids | mucin 12, cell surface associated; Involved in epithelial cell protection, adhesion modulation, and signaling. May be involved in epithelial cell growth regulation. Stimulated by both cytokine TNF-alpha and TGF- beta in intestinal epithelium | 0.900 |
B4GALT5 | MUC13 | ENSP00000360776 | ENSP00000312235 | UDP-Gal-betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5; Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids | mucin 13, cell surface associated; Epithelial and hemopoietic transmembrane mucin that may play a role in cell signaling | 0.900 |
B4GALT5 | MUC15 | ENSP00000360776 | ENSP00000416753 | UDP-Gal-betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5; Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids | mucin 15, cell surface associated; May play a role in the cell adhesion to the extracellular matrix | 0.900 |
B4GALT5 | MUC16 | ENSP00000360776 | ENSP00000381008 | UDP-Gal-betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5; Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids | mucin 16, cell surface associated; Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces (By similarity) | 0.900 |
B4GALT5 | MUC17 | ENSP00000360776 | ENSP00000302716 | UDP-Gal-betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5; Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids | mucin 17, cell surface associated; Probably plays a role in maintaining homeostasis on mucosal surfaces | 0.900 |
B4GALT5 | MUC19 | ENSP00000360776 | ENSP00000395253 | UDP-Gal-betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5; Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids | mucin 19, oligomeric; May function in ocular mucus homeostasis | 0.900 |
B4GALT5 | MUC2 | ENSP00000360776 | ENSP00000415183 | UDP-Gal-betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5; Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids | mucin 2, oligomeric mucus/gel-forming; Coats the epithelia of the intestines, airways, and other mucus membrane-containing organs. Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. Major constituent of both the inner and outer mucus layers of the colon and may play a role in excluding bacteria from the inner mucus layer | 0.900 |
B4GALT5 | MUC20 | ENSP00000360776 | ENSP00000396774 | UDP-Gal-betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5; Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids | mucin 20, cell surface associated; May regulate MET signaling cascade. Seems to decrease hepatocyte growth factor (HGF)-induced transient MAPK activation. Blocks GRB2 recruitment to MET thus suppressing the GRB2-RAS pathway. Inhibits HGF-induced proliferation of MMP1 and MMP9 expression | 0.900 |
B4GALT5 | MUC21 | ENSP00000360776 | ENSP00000365473 | UDP-Gal-betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5; Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids | mucin 21, cell surface associated | 0.900 |
B4GALT5 | MUC3A | ENSP00000360776 | ENSP00000324834 | UDP-Gal-betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5; Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids | mucin 3A, cell surface associated; Major glycoprotein component of a variety of mucus gels. Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces (By similarity) | 0.900 |
B4GALT5 | MUC4 | ENSP00000360776 | ENSP00000417498 | UDP-Gal-betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5; Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids | mucin 4, cell surface associated | 0.900 |
B4GALT5 | MUC5AC | ENSP00000360776 | ENSP00000435591 | UDP-Gal-betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5; Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids | mucin 5AC, oligomeric mucus/gel-forming | 0.900 |
B4GALT5 | MUC5B | ENSP00000360776 | ENSP00000436812 | UDP-Gal-betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5; Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids | mucin 5B, oligomeric mucus/gel-forming | 0.900 |
B4GALT5 | MUC6 | ENSP00000360776 | ENSP00000406861 | UDP-Gal-betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5; Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids | mucin 6, oligomeric mucus/gel-forming; May provide a mechanism for modulation of the composition of the protective mucus layer related to acid secretion or the presence of bacteria and noxious agents in the lumen. Plays an important role in the cytoprotection of epithelial surfaces and are used as tumor markers in a variety of cancers. May play a role in epithelial organogenesis | 0.900 |
B4GALT5 | MUC7 | ENSP00000360776 | ENSP00000302021 | UDP-Gal-betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5; Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids | mucin 7, secreted; May function in a protective capacity by promoting the clearance of bacteria in the oral cavity and aiding in mastication, speech, and swallowing. Binds P.aeruginosa pili | 0.900 |
B4GALT5 | MUCL1 | ENSP00000360776 | ENSP00000311364 | UDP-Gal-betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5; Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids | mucin-like 1; May play a role as marker for the diagnosis of metastatic breast cancer | 0.900 |
ELAVL1 | UBC | ENSP00000385269 | ENSP00000344818 | ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R); Involved in 3’-UTR ARE-mediated MYC stabilization. Binds avidly to the AU-rich element in FOS and IL3/interleukin-3 mRNAs. In the case of the FOS AU-rich element, HUR binds to a core element of 27 nucleotides that contain AUUUA, AUUUUA and AUUUUUA motifs. Binds preferentially to the 5’-UUUU[AG]UUU-3’ motif in vitro | ubiquitin C | 0.998 |
GCNT1 | B4GALT5 | ENSP00000365920 | ENSP00000360776 | glucosaminyl (N-acetyl) transferase 1, core 2; Forms critical branches in O-glycans | UDP-Gal-betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5; Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids | 0.908 |