node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ATP6V1D | ATP6V1E2 | ENSP00000216442 | ENSP00000304891 | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D; Subunit of the peripheral V1 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system (By similarity) | ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E2; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. This isoform is essential for energy coupling involved in acidification of acrosome (By similarity) | 0.998 |
ATP6V1D | C9orf16 | ENSP00000216442 | ENSP00000362085 | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D; Subunit of the peripheral V1 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system (By similarity) | chromosome 9 open reading frame 16 | 0.483 |
ATP6V1E2 | ATP6V1D | ENSP00000304891 | ENSP00000216442 | ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E2; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. This isoform is essential for energy coupling involved in acidification of acrosome (By similarity) | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D; Subunit of the peripheral V1 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system (By similarity) | 0.998 |
ATP6V1E2 | C9orf16 | ENSP00000304891 | ENSP00000362085 | ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E2; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. This isoform is essential for energy coupling involved in acidification of acrosome (By similarity) | chromosome 9 open reading frame 16 | 0.581 |
C9orf16 | ATP6V1D | ENSP00000362085 | ENSP00000216442 | chromosome 9 open reading frame 16 | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D; Subunit of the peripheral V1 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system (By similarity) | 0.483 |
C9orf16 | ATP6V1E2 | ENSP00000362085 | ENSP00000304891 | chromosome 9 open reading frame 16 | ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E2; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. This isoform is essential for energy coupling involved in acidification of acrosome (By similarity) | 0.581 |
C9orf16 | CEP290 | ENSP00000362085 | ENSP00000448012 | chromosome 9 open reading frame 16 | centrosomal protein 290kDa; Part of the tectonic-like complex which is required for tissue-specific ciliogenesis and may regulate ciliary membrane composition (By similarity). Activates ATF4-mediated transcription. Required for the correct localization of ciliary and phototransduction proteins in retinal photoreceptor cells; may play a role in ciliary transport processes | 0.608 |
C9orf16 | IKBIP | ENSP00000362085 | ENSP00000299157 | chromosome 9 open reading frame 16 | IKBKB interacting protein; Target of p53/TP53 with pro-apoptotic function | 0.548 |
C9orf16 | THAP11 | ENSP00000362085 | ENSP00000304689 | chromosome 9 open reading frame 16 | THAP domain containing 11; Transcriptional repressor that plays a central role for embryogenesis and the pluripotency of embryonic stem (ES) cells. Sequence-specific DNA-binding factor that represses gene expression in pluripotent ES cells by directly binding to key genetic loci and recruiting epigenetic modifiers (By similarity) | 0.475 |
CEP290 | C9orf16 | ENSP00000448012 | ENSP00000362085 | centrosomal protein 290kDa; Part of the tectonic-like complex which is required for tissue-specific ciliogenesis and may regulate ciliary membrane composition (By similarity). Activates ATF4-mediated transcription. Required for the correct localization of ciliary and phototransduction proteins in retinal photoreceptor cells; may play a role in ciliary transport processes | chromosome 9 open reading frame 16 | 0.608 |
IKBIP | C9orf16 | ENSP00000299157 | ENSP00000362085 | IKBKB interacting protein; Target of p53/TP53 with pro-apoptotic function | chromosome 9 open reading frame 16 | 0.548 |
THAP11 | C9orf16 | ENSP00000304689 | ENSP00000362085 | THAP domain containing 11; Transcriptional repressor that plays a central role for embryogenesis and the pluripotency of embryonic stem (ES) cells. Sequence-specific DNA-binding factor that represses gene expression in pluripotent ES cells by directly binding to key genetic loci and recruiting epigenetic modifiers (By similarity) | chromosome 9 open reading frame 16 | 0.475 |