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UTP18 | UTP18 small subunit (SSU) processome component homolog (yeast); Involved in nucleolar processing of pre-18S ribosomal RNA (By similarity) (556 aa) | |||
BYSL | bystin-like; Required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits. May be required for trophinin-dependent regulation of cell adhesion during implantation of human embryos (437 aa) | |||
DDX55 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 55; Probable ATP-binding RNA helicase (600 aa) | |||
FTSJ2 | FtsJ RNA methyltransferase homolog 2 (E. coli); Probable methyltransferase (246 aa) | |||
MPHOSPH10 | M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein); Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing (681 aa) | |||
RRP8 | ribosomal RNA processing 8, methyltransferase, homolog (yeast); Essential component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone-modifying enzymes. The eNoSC complex is able to sense the energy status of cell- upon glucose starvation, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at ’Lys- 9’ (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, [...] (456 aa) | |||
NOP58 | NOP58 ribonucleoprotein homolog (yeast); Required for 60S ribosomal subunit biogenesis (By similarity) (529 aa) | |||
CEP70 | centrosomal protein 70kDa (597 aa) | |||
PWP2 | PWP2 periodic tryptophan protein homolog (yeast) (919 aa) | |||
LARP1B | La ribonucleoprotein domain family, member 1B (914 aa) | |||
PRPF31 | PRP31 pre-mRNA processing factor 31 homolog (S. cerevisiae) (499 aa) | |||
CIRH1A | cirrhosis, autosomal recessive 1A (cirhin); May be a transcriptional regulator. Acts as a positive regulator of HIVEP1 which specifically binds to the DNA sequence 5’-GGGACTTTCC-3’ found in enhancer elements of numerous viral promoters such as those of HIV-1, SV40, or CMV (686 aa) | |||
NOC4L | nucleolar complex associated 4 homolog (S. cerevisiae) (516 aa) | |||
LARP1 | La ribonucleoprotein domain family, member 1 (1019 aa) | |||
UBC | ubiquitin C (685 aa) | |||
COG2 | component of oligomeric golgi complex 2; Required for normal Golgi morphology and function (738 aa) | |||
SURF6 | surfeit 6; Binds to both DNA and RNA in vitro, with a stronger binding capacity for RNA. May represent a nucleolar constitutive protein involved in ribosomal biosynthesis or assembly (By similarity) (361 aa) | |||
DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 (851 aa) | |||
UTP11L | UTP11-like, U3 small nucleolar ribonucleoprotein, (yeast); Involved in nucleolar processing of pre-18S ribosomal RNA (By similarity) (253 aa) | |||
EXOSC10 | exosome component 10; Putative catalytic component of the RNA exosome complex which has 3’->5’ exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding ’pervasive’ transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. [...] (885 aa) | |||
NOP56 | NOP56 ribonucleoprotein homolog (yeast); Involved in the early to middle stages of 60S ribosomal subunit biogenesis (594 aa) | |||
RPF2 | ribosome production factor 2 homolog (S. cerevisiae) (306 aa) | |||
SUMO2 | SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae); Ubiquitin-like protein that can be covalently attached to proteins as a monomer or as a lysine-linked polymer. Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such as PIAS1-4, RANBP2 or CBX4. This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduc [...] (95 aa) | |||
CNBP | CCHC-type zinc finger, nucleic acid binding protein (179 aa) | |||
ENSG00000248354 | Uncharacterized protein (205 aa) | |||
RSL1D1 | ribosomal L1 domain containing 1 (490 aa) |