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STRINGSTRING
SURF1 SURF1 GTP GTP SLC25A5 SLC25A5 SLC25A31 SLC25A31 SLC25A6 SLC25A6 PTEN PTEN SLC25A25 SLC25A25 UBC UBC DUSP1 DUSP1 SLC25A22 SLC25A22 SLC25A4 SLC25A4 MTG1 MTG1 DUSP12 DUSP12 SLC25A18 SLC25A18
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
DUSP1dual specificity phosphatase 1; Dual specificity phosphatase that dephosphorylates MAP kinase MAPK1/ERK2 on both ’Thr-183’ and ’Tyr-185’, regulating its activity during the meiotic cell cycle (By similarity) (367 aa)
SLC25A31solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31; Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane. May serve to mediate energy generating and energy consuming processes in the distal flagellum, possibly as a nucleotide shuttle between flagellar glycolysis, protein phosphorylation and mechanisms of motility (315 aa)
SLC25A4solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4; Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane (298 aa)
SLC25A22solute carrier family 25 (mitochondrial carrier- glutamate), member 22 (323 aa)
GTPMitochondrial GTPase 1 ; Mitochondrial GTPase. May be involved in assembly of the large ribosomal subunit (By similarity) (334 aa)
SLC25A18solute carrier family 25 (glutamate carrier), member 18; Involved in the transport of glutamate across the inner mitochondrial membrane. Glutamate is cotransported with H(+) (315 aa)
UBCubiquitin C (685 aa)
DUSP12dual specificity phosphatase 12 (340 aa)
SLC25A5solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5; Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation (298 aa)
PTENphosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase, removing the phosphate in the D3 position of the inositol ring from phosphatidylinositol 3,4,5-trisphosphate, phosphatidylinositol 3,4-diphosphate, phosphatidylinositol 3- phosphate and inositol 1,3,4,5-tetrakisphosphate with order of substrate preference in vitro PtdIns(3,4,5)P3 > PtdIns(3,4)P2 > PtdIns3P > Ins(1,3,4,5)P4. The lipid phosphatase activity is critical for its tumor [...] (403 aa)
SURF1surfeit 1; Probably involved in the biogenesis of the COX complex (300 aa)
SLC25A25solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25 (503 aa)
SLC25A6solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6; Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane. May participate in the formation of the permeability transition pore complex (PTPC) responsible for the release of mitochondrial products that triggers apoptosis (298 aa)
MTG1mitochondrial GTPase 1 homolog (S. cerevisiae); Mitochondrial GTPase. May be involved in assembly of the large ribosomal subunit (By similarity) (339 aa)
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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