23 items (Homo sapiens) - STRING network view

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Size

small nodes:
protein of unknown 3D structure

large nodes:
some 3D structure is known or predicted

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SLC13A1	solute carrier family 13 (sodium/sulfate symporters), member 1; Sodium/sulfate cotransporter that mediates sulfate reabsorption in the kidney (595 aa)
	ABHD11	abhydrolase domain containing 11 (315 aa)
	RNF103	ring finger protein 103; Acts as an E2-dependent E3 ubiquitin-protein ligase, probably involved in the ER-associated protein degradation pathway (685 aa)
	EPHX1	epoxide hydrolase 1, microsomal (xenobiotic) (455 aa)
	ABHD10	abhydrolase domain containing 10; Catalyzes the deglucuronidation of mycophenolic acid acyl-glucuronide, a metabolite of the immunosuppressant drug mycophenolate (306 aa)
	ABHD14A	abhydrolase domain containing 14A; Possible role in granule neuron development (By similarity) (271 aa)
	SLC2A13	solute carrier family 2 (facilitated glucose transporter), member 13; H(+)-myo-inositol cotransporter. Can also transport related stereoisomers (648 aa)
	ZSWIM2	zinc finger, SWIM-type containing 2; E3 ubiquitin-protein ligase involved in the regulation of Fas-, DR3- and DR4-mediated apoptosis. Functions in conjunction with the UBE2D1, UBE2D3 and UBE2E1 E2 ubiquitin-conjugating enzymes (By similarity) (633 aa)
	SLC13A4	solute carrier family 13 (sodium/sulfate symporters), member 4; Sodium/sulfate cotransporter that mediates sulfate reabsorption in the high endothelial venules (HEV) (626 aa)
	PPME1	protein phosphatase methylesterase 1; Demethylates proteins that have been reversibly carboxymethylated. Demethylates PPP2CB (in vitro) and PPP2CA. Binding to PPP2CA displaces the manganese ion and inactivates the enzyme (386 aa)
	SERHL2	serine hydrolase-like 2; Probable serine hydrolase. May be related to cell muscle hypertrophy (314 aa)
	LIPA	lipase A, lysosomal acid, cholesterol esterase; Crucial for the intracellular hydrolysis of cholesteryl esters and triglycerides that have been internalized via receptor- mediated endocytosis of lipoprotein particles. Important in mediating the effect of LDL (low density lipoprotein) uptake on suppression of hydroxymethylglutaryl-CoA reductase and activation of endogenous cellular cholesteryl ester formation (399 aa)
	ABHD14B	abhydrolase domain containing 14B; Has hydrolase activity towards p-nitrophenyl butyrate (in vitro). May activate transcription (210 aa)
	LIPJ	lipase, family member J (366 aa)
	SLC29A3	solute carrier family 29 (nucleoside transporters), member 3 (475 aa)
	LIPF	lipase, gastric (408 aa)
	LIPK	lipase, family member K; Plays a highly specific role in the last step of keratinocyte differentiation. May have an essential function in lipid metabolism of the most differentiated epidermal layers (399 aa)
	LIPM	lipase, family member M; Plays a highly specific role in the last step of keratinocyte differentiation. May have an essential function in lipid metabolism of the most differentiated epidermal layers (423 aa)
	LIPN	lipase, family member N; Plays a highly specific role in the last step of keratinocyte differentiation. May have an essential function in lipid metabolism of the most differentiated epidermal layers (398 aa)
	ABHD5	abhydrolase domain containing 5; Lysophosphatidic acid acyltransferase which functions in phosphatidic acid biosynthesis. May regulate the cellular storage of triacylglycerol through activation of the phospholipase PNPLA2. Involved in keratinocyte differentiation (349 aa)
	ENSG00000249884	RNF103-CHMP3 readthrough (221 aa)
	CHMP3	charged multivesicular body protein 3 (251 aa)
	ABHD4	abhydrolase domain containing 4; Lysophospholipase selective for N-acyl phosphatidylethanolamine (NAPE). Contributes to the biosynthesis of N-acyl ethanolamines, including the endocannabinoid anandamide by hydrolyzing the sn-1 and sn-2 acyl chains from N-acyl phosphatidylethanolamine (NAPE) generating glycerophospho-N-acyl ethanolamine (GP-NAE), an intermediate for N-acyl ethanolamine biosynthesis. Hydrolyzes substrates bearing saturated, monounsaturated, polyunsaturated N-acyl chains. Shows no significant activity towards other lysophospholipids, including lysophosphatidylcholine, lys [...] (342 aa)