node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADAMTS14 | BMP1 | ENSP00000362304 | ENSP00000305714 | ADAM metallopeptidase with thrombospondin type 1 motif, 14; Has a aminoprocollagen type I activity processing activity in the absence of ADAMTS2. Seems to be synthesized as a latent enzyme that requires activation to display aminoprocollagen peptidase activity | bone morphogenetic protein 1 | 0.944 |
ADAMTS14 | PCOLCE | ENSP00000362304 | ENSP00000223061 | ADAM metallopeptidase with thrombospondin type 1 motif, 14; Has a aminoprocollagen type I activity processing activity in the absence of ADAMTS2. Seems to be synthesized as a latent enzyme that requires activation to display aminoprocollagen peptidase activity | procollagen C-endopeptidase enhancer; Binds to the C-terminal propeptide of type I procollagen and enhances procollagen C-proteinase activity | 0.921 |
ADAMTS14 | PCOLCE2 | ENSP00000362304 | ENSP00000295992 | ADAM metallopeptidase with thrombospondin type 1 motif, 14; Has a aminoprocollagen type I activity processing activity in the absence of ADAMTS2. Seems to be synthesized as a latent enzyme that requires activation to display aminoprocollagen peptidase activity | procollagen C-endopeptidase enhancer 2; Binds to the C-terminal propeptide of types I and II procollagens and may enhance the cleavage of that propeptide by BMP1 | 0.909 |
ADAMTS14 | TLL1 | ENSP00000362304 | ENSP00000061240 | ADAM metallopeptidase with thrombospondin type 1 motif, 14; Has a aminoprocollagen type I activity processing activity in the absence of ADAMTS2. Seems to be synthesized as a latent enzyme that requires activation to display aminoprocollagen peptidase activity | tolloid-like 1; Protease which processes procollagen C-propeptides, such as chordin, pro-biglycan and pro-lysyl oxidase. Required for the embryonic development. Predominant protease, which in the development, influences dorsal-ventral patterning and skeletogenesis | 0.947 |
BMP1 | ADAMTS14 | ENSP00000305714 | ENSP00000362304 | bone morphogenetic protein 1 | ADAM metallopeptidase with thrombospondin type 1 motif, 14; Has a aminoprocollagen type I activity processing activity in the absence of ADAMTS2. Seems to be synthesized as a latent enzyme that requires activation to display aminoprocollagen peptidase activity | 0.944 |
BMP1 | PCOLCE | ENSP00000305714 | ENSP00000223061 | bone morphogenetic protein 1 | procollagen C-endopeptidase enhancer; Binds to the C-terminal propeptide of type I procollagen and enhances procollagen C-proteinase activity | 0.922 |
BMP1 | PCOLCE2 | ENSP00000305714 | ENSP00000295992 | bone morphogenetic protein 1 | procollagen C-endopeptidase enhancer 2; Binds to the C-terminal propeptide of types I and II procollagens and may enhance the cleavage of that propeptide by BMP1 | 0.921 |
BMP1 | TLL1 | ENSP00000305714 | ENSP00000061240 | bone morphogenetic protein 1 | tolloid-like 1; Protease which processes procollagen C-propeptides, such as chordin, pro-biglycan and pro-lysyl oxidase. Required for the embryonic development. Predominant protease, which in the development, influences dorsal-ventral patterning and skeletogenesis | 0.901 |
PCOLCE | ADAMTS14 | ENSP00000223061 | ENSP00000362304 | procollagen C-endopeptidase enhancer; Binds to the C-terminal propeptide of type I procollagen and enhances procollagen C-proteinase activity | ADAM metallopeptidase with thrombospondin type 1 motif, 14; Has a aminoprocollagen type I activity processing activity in the absence of ADAMTS2. Seems to be synthesized as a latent enzyme that requires activation to display aminoprocollagen peptidase activity | 0.921 |
PCOLCE | BMP1 | ENSP00000223061 | ENSP00000305714 | procollagen C-endopeptidase enhancer; Binds to the C-terminal propeptide of type I procollagen and enhances procollagen C-proteinase activity | bone morphogenetic protein 1 | 0.922 |
PCOLCE2 | ADAMTS14 | ENSP00000295992 | ENSP00000362304 | procollagen C-endopeptidase enhancer 2; Binds to the C-terminal propeptide of types I and II procollagens and may enhance the cleavage of that propeptide by BMP1 | ADAM metallopeptidase with thrombospondin type 1 motif, 14; Has a aminoprocollagen type I activity processing activity in the absence of ADAMTS2. Seems to be synthesized as a latent enzyme that requires activation to display aminoprocollagen peptidase activity | 0.909 |
PCOLCE2 | BMP1 | ENSP00000295992 | ENSP00000305714 | procollagen C-endopeptidase enhancer 2; Binds to the C-terminal propeptide of types I and II procollagens and may enhance the cleavage of that propeptide by BMP1 | bone morphogenetic protein 1 | 0.921 |
TLL1 | ADAMTS14 | ENSP00000061240 | ENSP00000362304 | tolloid-like 1; Protease which processes procollagen C-propeptides, such as chordin, pro-biglycan and pro-lysyl oxidase. Required for the embryonic development. Predominant protease, which in the development, influences dorsal-ventral patterning and skeletogenesis | ADAM metallopeptidase with thrombospondin type 1 motif, 14; Has a aminoprocollagen type I activity processing activity in the absence of ADAMTS2. Seems to be synthesized as a latent enzyme that requires activation to display aminoprocollagen peptidase activity | 0.947 |
TLL1 | BMP1 | ENSP00000061240 | ENSP00000305714 | tolloid-like 1; Protease which processes procollagen C-propeptides, such as chordin, pro-biglycan and pro-lysyl oxidase. Required for the embryonic development. Predominant protease, which in the development, influences dorsal-ventral patterning and skeletogenesis | bone morphogenetic protein 1 | 0.901 |