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RHBDD2 | rhomboid domain containing 2 (364 aa) | |||
RHBDD3 | rhomboid domain containing 3 (386 aa) | |||
ERBB3 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian); Binds and is activated by neuregulins and NTAK (1342 aa) | |||
ZDHHC11 | zinc finger, DHHC-type containing 11 (412 aa) | |||
ZDHHC5 | zinc finger, DHHC-type containing 5; Palmitoyl acyltransferase for the G-protein coupled receptor SSTR5. Also palmitoylates FLOT2 (By similarity) (715 aa) | |||
ZDHHC3 | zinc finger, DHHC-type containing 3; Palmitoyltransferase with broad specificity. Palmitoylates GABA receptors on their gamma subunit (GABRG1, GABRG2 and GABRG3), which regulates synaptic clustering and/or cell surface stability. Palmitoylates glutamate receptors GRIA1 and GRIA2, which leads to their retention in Golgi (By similarity) (327 aa) | |||
ZDHHC19 | zinc finger, DHHC-type containing 19 (309 aa) | |||
ZDHHC24 | zinc finger, DHHC-type containing 24 (284 aa) | |||
ZDHHC22 | zinc finger, DHHC-type containing 22 (263 aa) | |||
ZDHHC23 | zinc finger, DHHC-type containing 23; May be involved in NOS1 regulation and targeting to the synaptic membrane (By similarity) (409 aa) | |||
ZDHHC1 | zinc finger, DHHC-type containing 1 (485 aa) | |||
ZDHHC7 | zinc finger, DHHC-type containing 7; Palmitoyltransferase with broad specificity. Palmitoylates SNAP25 and DLG4/PSD95. May palmitoylate GABA receptors on their gamma subunit (GABRG1, GABRG2 and GABRG3) and thereby regulate their synaptic clustering and/or cell surface stability (By similarity). Palmitoylates sex steroid hormone receptors, including ESR1, PGR and AR, thereby regulating their targeting to the plasma membrane. This affects rapid intracellular signaling by sex hormones via ERK and AKT kinases and the generation of cAMP, but does not affect that mediated by their nuclear re [...] (345 aa) | |||
RHBDD1 | rhomboid domain containing 1; Intramembrane-cleaving serine protease that cleaves single transmembrane or multi-pass membrane proteins in the hydrophobic plane of the membrane, luminal loops and juxtamembrane regions. Involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors. Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded membrane proteins. Required for the degradation process of some specific misfolded endoplasmic reticulum (ER) luminal proteins. Participates in the trans [...] (315 aa) | |||
ZDHHC9 | zinc finger, DHHC-type containing 9 (364 aa) | |||
ZDHHC14 | zinc finger, DHHC-type containing 14 (488 aa) | |||
STX7 | syntaxin 7; May be involved in protein trafficking from the plasma membrane to the early endosome (EE) as well as in homotypic fusion of endocytic organelles. Mediates the endocytic trafficking from early endosomes to late endosomes and lysosomes (261 aa) | |||
ZDHHC12 | zinc finger, DHHC-type containing 12 (267 aa) | |||
ZDHHC18 | zinc finger, DHHC-type containing 18; Has palmitoyltransferase activity towards HRAS and LCK (By similarity) (388 aa) | |||
SLC31A1 | solute carrier family 31 (copper transporters), member 1; High-affinity, saturable copper transporter involved in dietary copper uptake (190 aa) | |||
ZDHHC21 | zinc finger, DHHC-type containing 21; Palmitoylates sex steroid hormone receptors, including ESR1, PGR and AR, thereby regulating their targeting to the plasma membrane. This affects rapid intracellular signaling by sex hormones via ERK and AKT kinases and the generation of cAMP, but does not affect that mediated by their nuclear receptor (By similarity) (265 aa) | |||
ZDHHC8 | zinc finger, DHHC-type containing 8; Palmitoyltransferase involved in glutamatergic transmission. Mediates palmitoylation of ABCA1 (778 aa) | |||
CCS | copper chaperone for superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) (274 aa) | |||
ZDHHC11B | zinc finger, DHHC-type containing 11B (382 aa) |