adenylate cyclase 4; This is a membrane-bound, calmodulin-insensitive adenylyl cyclase (By similarity)

adrenoceptor alpha 2B; Alpha-2 adrenergic receptors mediate the catecholamine- induced inhibition of adenylate cyclase through the action of G proteins. The rank order of potency for agonists of this receptor is clonidine > norepinephrine > epinephrine = oxymetazoline > dopamine > p-tyramine = phenylephrine > serotonin > p-synephrine / p-octopamine. For antagonists, the rank order is yohimbine > chlorpromazine > phentolamine > mianserine > spiperone > prazosin > alprenolol > propanolol > pindolol

adenylate cyclase 4; This is a membrane-bound, calmodulin-insensitive adenylyl cyclase (By similarity)

annexin A1; Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis. This protein regulates phospholipase A2 activity. It seems to bind from two to four calcium ions with high affinity

adenylate cyclase 4; This is a membrane-bound, calmodulin-insensitive adenylyl cyclase (By similarity)

bradykinin receptor B2; Receptor for bradykinin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system

adenylate cyclase 4; This is a membrane-bound, calmodulin-insensitive adenylyl cyclase (By similarity)

complement component 5; Activation of C5 by a C5 convertase initiates the spontaneous assembly of the late complement components, C5-C9, into the membrane attack complex. C5b has a transient binding site for C6. The C5b-C6 complex is the foundation upon which the lytic complex is assembled

adenylate cyclase 4; This is a membrane-bound, calmodulin-insensitive adenylyl cyclase (By similarity)

chemokine (C-C motif) ligand 28; Chemotactic activity for resting CD4, CD8 T-cells and eosinophils. Binds to CCR3 and CCR10 and induces calcium mobilization in a dose-dependent manner

adenylate cyclase 4; This is a membrane-bound, calmodulin-insensitive adenylyl cyclase (By similarity)

chemokine (C-C motif) receptor 6; Receptor for a C-C type chemokine. Binds to MIP-3- alpha/LARC and subsequently transduces a signal by increasing the intracellular calcium ions level

adenylate cyclase 4; This is a membrane-bound, calmodulin-insensitive adenylyl cyclase (By similarity)

chemokine (C-C motif) receptor 8; Receptor for the chemokine CCL1/SCYA1/I-309. May regulate monocyte chemotaxis and thymic cell line apoptosis. Alternative coreceptor with CD4 for HIV-1 infection

adenylate cyclase 4; This is a membrane-bound, calmodulin-insensitive adenylyl cyclase (By similarity)

hydroxycarboxylic acid receptor 3; Receptor for 3-OH-octanoid acid mediates a negative feedback regulation of adipocyte lipolysis to counteract prolipolytic influences under conditions of physiological or pathological increases in beta-oxidation rates. Acts as a low affinity receptor for nicotinic acid. This pharmacological effect requires nicotinic acid doses that are much higher than those provided by a normal diet

adenylate cyclase 4; This is a membrane-bound, calmodulin-insensitive adenylyl cyclase (By similarity)

histamine receptor H3; The H3 subclass of histamine receptors could mediate the histamine signals in CNS and peripheral nervous system. Signals through the inhibition of adenylate cyclase and displays high constitutive activity (spontaneous activity in the absence of agonist). Agonist stimulation of isoform 3 neither modified adenylate cyclase activity nor induced intracellular calcium mobilization

adenylate cyclase 4; This is a membrane-bound, calmodulin-insensitive adenylyl cyclase (By similarity)

melanin-concentrating hormone receptor 2; Receptor for melanin-concentrating hormone, coupled to G proteins that activate phosphoinositide hydrolysis

adenylate cyclase 4; This is a membrane-bound, calmodulin-insensitive adenylyl cyclase (By similarity)

neuromedin U receptor 1; Receptor for the neuromedin-U and neuromedin-S neuropeptides (By similarity)

adenylate cyclase 4; This is a membrane-bound, calmodulin-insensitive adenylyl cyclase (By similarity)

neuropeptide Y receptor Y5; Receptor for neuropeptide Y and peptide YY. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. Seems to be associated with food intake. Could be involved in feeding disorders

adenylate cyclase 4; This is a membrane-bound, calmodulin-insensitive adenylyl cyclase (By similarity)

opiate receptor-like 1; Receptor for the neuropeptide nociceptin/orphanin FQ. Has a potential role in modulating a number of brain functions, including instinctive behaviors and emotions. The activity of this receptor is mediated by G proteins which inhibits adenylyl cyclase

adenylate cyclase 4; This is a membrane-bound, calmodulin-insensitive adenylyl cyclase (By similarity)

opioid receptor, mu 1

adenylate cyclase 4; This is a membrane-bound, calmodulin-insensitive adenylyl cyclase (By similarity)

pyrimidinergic receptor P2Y, G-protein coupled, 4; Receptor for UTP and UDP coupled to G-proteins that activate a phosphatidylinositol-calcium second messenger system. Not activated by ATP or ADP

adenylate cyclase 4; This is a membrane-bound, calmodulin-insensitive adenylyl cyclase (By similarity)

proenkephalin; Met- and Leu-enkephalins compete with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress. PENK(114-133) and PENK(237-258) increase glutamate release in the striatum. PENK(114-133) decreases GABA concentration in the striatum

adenylate cyclase 4; This is a membrane-bound, calmodulin-insensitive adenylyl cyclase (By similarity)

sphingosine-1-phosphate receptor 1; Receptor for the lysosphingolipid sphingosine 1- phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. This inducible epithelial cell G-protein-coupled receptor may be involved in the processes that regulate the differentiation of endothelial cells. Seems to be coupled to the G(i) subclass of heteromeric G proteins

adenylate cyclase 4; This is a membrane-bound, calmodulin-insensitive adenylyl cyclase (By similarity)

somatostatin receptor 1; Receptor for somatostatin with higher affinity for somatostatin-14 than -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and Na(+)/H(+) exchanger via pertussis toxin insensitive G proteins

adenylate cyclase 4; This is a membrane-bound, calmodulin-insensitive adenylyl cyclase (By similarity)

somatostatin receptor 3; Receptor for somatostatins-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase

adenylate cyclase 4; This is a membrane-bound, calmodulin-insensitive adenylyl cyclase (By similarity)

taste receptor, type 2, member 40; Gustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5