node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MNF1 | UQCC | ENSP00000363348 | ENSP00000363506 | mitochondrial nucleoid factor 1 | ubiquinol-cytochrome c reductase complex chaperone | 0.710 |
MT-CYB | PMPCA | ENSP00000354554 | ENSP00000360782 | mitochondrially encoded cytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) | peptidase (mitochondrial processing) alpha; Cleaves presequences (transit peptides) from mitochondrial protein precursors (By similarity) | 0.595 |
MT-CYB | PMPCB | ENSP00000354554 | ENSP00000249269 | mitochondrially encoded cytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) | peptidase (mitochondrial processing) beta; Cleaves presequences (transit peptides) from mitochondrial protein precursors (By similarity) | 0.833 |
MT-CYB | UQCC | ENSP00000354554 | ENSP00000363506 | mitochondrially encoded cytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) | ubiquinol-cytochrome c reductase complex chaperone | 0.589 |
MT-CYB | UQCRC1 | ENSP00000354554 | ENSP00000203407 | mitochondrially encoded cytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) | ubiquinol-cytochrome c reductase core protein I; This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1 | 0.985 |
MT-CYB | UQCRC2 | ENSP00000354554 | ENSP00000268379 | mitochondrially encoded cytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) | ubiquinol-cytochrome c reductase core protein II; This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. The core protein 2 is required for the assembly of the complex | 0.992 |
PMPCA | MT-CYB | ENSP00000360782 | ENSP00000354554 | peptidase (mitochondrial processing) alpha; Cleaves presequences (transit peptides) from mitochondrial protein precursors (By similarity) | mitochondrially encoded cytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) | 0.595 |
PMPCA | PMPCB | ENSP00000360782 | ENSP00000249269 | peptidase (mitochondrial processing) alpha; Cleaves presequences (transit peptides) from mitochondrial protein precursors (By similarity) | peptidase (mitochondrial processing) beta; Cleaves presequences (transit peptides) from mitochondrial protein precursors (By similarity) | 0.995 |
PMPCA | UQCRC1 | ENSP00000360782 | ENSP00000203407 | peptidase (mitochondrial processing) alpha; Cleaves presequences (transit peptides) from mitochondrial protein precursors (By similarity) | ubiquinol-cytochrome c reductase core protein I; This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1 | 0.893 |
PMPCB | MT-CYB | ENSP00000249269 | ENSP00000354554 | peptidase (mitochondrial processing) beta; Cleaves presequences (transit peptides) from mitochondrial protein precursors (By similarity) | mitochondrially encoded cytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) | 0.833 |
PMPCB | PMPCA | ENSP00000249269 | ENSP00000360782 | peptidase (mitochondrial processing) beta; Cleaves presequences (transit peptides) from mitochondrial protein precursors (By similarity) | peptidase (mitochondrial processing) alpha; Cleaves presequences (transit peptides) from mitochondrial protein precursors (By similarity) | 0.995 |
PMPCB | UQCC | ENSP00000249269 | ENSP00000363506 | peptidase (mitochondrial processing) beta; Cleaves presequences (transit peptides) from mitochondrial protein precursors (By similarity) | ubiquinol-cytochrome c reductase complex chaperone | 0.558 |
PMPCB | UQCRC2 | ENSP00000249269 | ENSP00000268379 | peptidase (mitochondrial processing) beta; Cleaves presequences (transit peptides) from mitochondrial protein precursors (By similarity) | ubiquinol-cytochrome c reductase core protein II; This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. The core protein 2 is required for the assembly of the complex | 0.975 |
SETD1A | SETD1B | ENSP00000262519 | ENSP00000267197 | SET domain containing 1A; Histone methyltransferase that specifically methylates ’Lys-4’ of histone H3, when part of the SET1 histone methyltransferase (HMT) complex, but not if the neighboring ’Lys- 9’ residue is already methylated. H3 ’Lys-4’ methylation represents a specific tag for epigenetic transcriptional activation. The non-overalpping localization with SETD1B suggests that SETD1A and SETD1B make non-redundant contributions to the epigenetic control of chromatin structure and gene expression | SET domain containing 1B; Histone methyltransferase that specifically methylates ’Lys-4’ of histone H3, when part of the SET1 histone methyltransferase (HMT) complex, but not if the neighboring ’Lys- 9’ residue is already methylated. H3 ’Lys-4’ methylation represents a specific tag for epigenetic transcriptional activation. The non-overalpping localization with SETD1A suggests that SETD1A and SETD1B make non-redundant contributions to the epigenetic control of chromatin structure and gene expression. Specifically tri-methylates ’Lys-4’ of histone H3 in vitro | 0.933 |
SETD1A | UQCC | ENSP00000262519 | ENSP00000363506 | SET domain containing 1A; Histone methyltransferase that specifically methylates ’Lys-4’ of histone H3, when part of the SET1 histone methyltransferase (HMT) complex, but not if the neighboring ’Lys- 9’ residue is already methylated. H3 ’Lys-4’ methylation represents a specific tag for epigenetic transcriptional activation. The non-overalpping localization with SETD1B suggests that SETD1A and SETD1B make non-redundant contributions to the epigenetic control of chromatin structure and gene expression | ubiquinol-cytochrome c reductase complex chaperone | 0.594 |
SETD1B | SETD1A | ENSP00000267197 | ENSP00000262519 | SET domain containing 1B; Histone methyltransferase that specifically methylates ’Lys-4’ of histone H3, when part of the SET1 histone methyltransferase (HMT) complex, but not if the neighboring ’Lys- 9’ residue is already methylated. H3 ’Lys-4’ methylation represents a specific tag for epigenetic transcriptional activation. The non-overalpping localization with SETD1A suggests that SETD1A and SETD1B make non-redundant contributions to the epigenetic control of chromatin structure and gene expression. Specifically tri-methylates ’Lys-4’ of histone H3 in vitro | SET domain containing 1A; Histone methyltransferase that specifically methylates ’Lys-4’ of histone H3, when part of the SET1 histone methyltransferase (HMT) complex, but not if the neighboring ’Lys- 9’ residue is already methylated. H3 ’Lys-4’ methylation represents a specific tag for epigenetic transcriptional activation. The non-overalpping localization with SETD1B suggests that SETD1A and SETD1B make non-redundant contributions to the epigenetic control of chromatin structure and gene expression | 0.933 |
SETD1B | UQCC | ENSP00000267197 | ENSP00000363506 | SET domain containing 1B; Histone methyltransferase that specifically methylates ’Lys-4’ of histone H3, when part of the SET1 histone methyltransferase (HMT) complex, but not if the neighboring ’Lys- 9’ residue is already methylated. H3 ’Lys-4’ methylation represents a specific tag for epigenetic transcriptional activation. The non-overalpping localization with SETD1A suggests that SETD1A and SETD1B make non-redundant contributions to the epigenetic control of chromatin structure and gene expression. Specifically tri-methylates ’Lys-4’ of histone H3 in vitro | ubiquinol-cytochrome c reductase complex chaperone | 0.572 |
UQCC | MNF1 | ENSP00000363506 | ENSP00000363348 | ubiquinol-cytochrome c reductase complex chaperone | mitochondrial nucleoid factor 1 | 0.710 |
UQCC | MT-CYB | ENSP00000363506 | ENSP00000354554 | ubiquinol-cytochrome c reductase complex chaperone | mitochondrially encoded cytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) | 0.589 |
UQCC | PMPCB | ENSP00000363506 | ENSP00000249269 | ubiquinol-cytochrome c reductase complex chaperone | peptidase (mitochondrial processing) beta; Cleaves presequences (transit peptides) from mitochondrial protein precursors (By similarity) | 0.558 |