node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CD4 | HLA-A | ENSP00000011653 | ENSP00000366005 | CD4 molecule; Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation. Induces the aggregation of lipid rafts | major histocompatibility complex, class I, A; Involved in the presentation of foreign antigens to the immune system (By similarity) | 0.565 |
CD4 | HLA-B | ENSP00000011653 | ENSP00000399168 | CD4 molecule; Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation. Induces the aggregation of lipid rafts | major histocompatibility complex, class I, B; Involved in the presentation of foreign antigens to the immune system (By similarity) | 0.538 |
CD4 | HLA-C | ENSP00000011653 | ENSP00000365402 | CD4 molecule; Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation. Induces the aggregation of lipid rafts | major histocompatibility complex, class I, C; Involved in the presentation of foreign antigens to the immune system (By similarity) | 0.489 |
CD4 | HLA-DPB1 | ENSP00000011653 | ENSP00000408146 | CD4 molecule; Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation. Induces the aggregation of lipid rafts | major histocompatibility complex, class II, DP beta 1 | 0.678 |
CD4 | HLA-DQA2 | ENSP00000011653 | ENSP00000364076 | CD4 molecule; Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation. Induces the aggregation of lipid rafts | major histocompatibility complex, class II, DQ alpha 2 | 0.755 |
CD4 | HLA-DQB1 | ENSP00000011653 | ENSP00000382034 | CD4 molecule; Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation. Induces the aggregation of lipid rafts | major histocompatibility complex, class II, DQ beta 1 | 0.863 |
CD4 | HLA-DRB1 | ENSP00000011653 | ENSP00000353099 | CD4 molecule; Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation. Induces the aggregation of lipid rafts | major histocompatibility complex, class II, DR beta 1 | 0.950 |
CD4 | HLA-G | ENSP00000011653 | ENSP00000353472 | CD4 molecule; Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation. Induces the aggregation of lipid rafts | major histocompatibility complex, class I, G; Involved in the presentation of foreign antigens to the immune system. Plays a role in maternal tolerance of the fetus by mediating protection from the deleterious effects of natural killer cells, cytotoxic T-lymphocytes, macrophages and mononuclear cells | 0.492 |
CD4 | INS | ENSP00000011653 | ENSP00000250971 | CD4 molecule; Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation. Induces the aggregation of lipid rafts | insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver (By similarity) | 0.504 |
HLA-A | CD4 | ENSP00000366005 | ENSP00000011653 | major histocompatibility complex, class I, A; Involved in the presentation of foreign antigens to the immune system (By similarity) | CD4 molecule; Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation. Induces the aggregation of lipid rafts | 0.565 |
HLA-A | HLA-B | ENSP00000366005 | ENSP00000399168 | major histocompatibility complex, class I, A; Involved in the presentation of foreign antigens to the immune system (By similarity) | major histocompatibility complex, class I, B; Involved in the presentation of foreign antigens to the immune system (By similarity) | 0.901 |
HLA-A | HLA-C | ENSP00000366005 | ENSP00000365402 | major histocompatibility complex, class I, A; Involved in the presentation of foreign antigens to the immune system (By similarity) | major histocompatibility complex, class I, C; Involved in the presentation of foreign antigens to the immune system (By similarity) | 0.900 |
HLA-A | HLA-DRB1 | ENSP00000366005 | ENSP00000353099 | major histocompatibility complex, class I, A; Involved in the presentation of foreign antigens to the immune system (By similarity) | major histocompatibility complex, class II, DR beta 1 | 0.910 |
HLA-A | HLA-DRB5 | ENSP00000366005 | ENSP00000364114 | major histocompatibility complex, class I, A; Involved in the presentation of foreign antigens to the immune system (By similarity) | major histocompatibility complex, class II, DR beta 5 | 0.902 |
HLA-A | HLA-G | ENSP00000366005 | ENSP00000353472 | major histocompatibility complex, class I, A; Involved in the presentation of foreign antigens to the immune system (By similarity) | major histocompatibility complex, class I, G; Involved in the presentation of foreign antigens to the immune system. Plays a role in maternal tolerance of the fetus by mediating protection from the deleterious effects of natural killer cells, cytotoxic T-lymphocytes, macrophages and mononuclear cells | 0.544 |
HLA-B | CD4 | ENSP00000399168 | ENSP00000011653 | major histocompatibility complex, class I, B; Involved in the presentation of foreign antigens to the immune system (By similarity) | CD4 molecule; Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation. Induces the aggregation of lipid rafts | 0.538 |
HLA-B | HLA-A | ENSP00000399168 | ENSP00000366005 | major histocompatibility complex, class I, B; Involved in the presentation of foreign antigens to the immune system (By similarity) | major histocompatibility complex, class I, A; Involved in the presentation of foreign antigens to the immune system (By similarity) | 0.901 |
HLA-B | HLA-C | ENSP00000399168 | ENSP00000365402 | major histocompatibility complex, class I, B; Involved in the presentation of foreign antigens to the immune system (By similarity) | major histocompatibility complex, class I, C; Involved in the presentation of foreign antigens to the immune system (By similarity) | 0.900 |
HLA-B | HLA-DRB1 | ENSP00000399168 | ENSP00000353099 | major histocompatibility complex, class I, B; Involved in the presentation of foreign antigens to the immune system (By similarity) | major histocompatibility complex, class II, DR beta 1 | 0.908 |
HLA-B | HLA-DRB5 | ENSP00000399168 | ENSP00000364114 | major histocompatibility complex, class I, B; Involved in the presentation of foreign antigens to the immune system (By similarity) | major histocompatibility complex, class II, DR beta 5 | 0.902 |