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STRINGSTRING
B3GNT5 B3GNT5 B3GNT4 B3GNT4 B3GNT2 B3GNT2 GALNT14 GALNT14 GALNT2 GALNT2 GALNT8 GALNT8 GALNT3 GALNT3 C1GALT1C1 C1GALT1C1 MUC17 MUC17 GALNT10 GALNT10 MUCL1 MUCL1 C1GALT1 C1GALT1 GALNT1 GALNT1 MUC13 MUC13 GALNT6 GALNT6 MUC3A MUC3A MUC21 MUC21 ST6GALNAC1 ST6GALNAC1 GALNT12 GALNT12 B3GNT7 B3GNT7 GALNT7 GALNT7 GALNT11 GALNT11 GALNTL2 GALNTL2 B3GNT3 B3GNT3 GCNT1 GCNT1 B3GNT8 B3GNT8
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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protein of unknown 3D structure
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second shell of interactors
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ST6GALNAC1ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 (600 aa)
C1GALT1core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1; Glycosyltransferase that generates the core 1 O-glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins. Plays a central role in many processes, such as angiogenesis, thrombopoiesis and kidney homeostasis development (363 aa)
GALNT8UDP-N-acetyl-alpha-D-galactosamine-polypeptide N-acetylgalactosaminyltransferase 8 (GalNAc-T8); Probably catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor (By similarity) (637 aa)
GALNT7UDP-N-acetyl-alpha-D-galactosamine-polypeptide N-acetylgalactosaminyltransferase 7 (GalNAc-T7); Glycopeptide transferase involved in O-linked oligosaccharide biosynthesis, which catalyzes the transfer of an N-acetyl-D-galactosamine residue to an already glycosylated peptide. In contrast to other proteins of the family, it does not act as a peptide transferase that transfers GalNAc onto serine or threonine residue on the protein receptor, but instead requires the prior addition of a GalNAc on a peptide before adding additional GalNAc moieties. Some peptide transferase activity is howeve [...] (657 aa)
GALNT1UDP-N-acetyl-alpha-D-galactosamine-polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1); Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor. Has a broad spectrum of substrates for peptides such as EA2, Muc5AC, Muc1a, Muc1b and Muc7 (559 aa)
B3GNT7UDP-GlcNAc-betaGal beta-1,3-N-acetylglucosaminyltransferase 7; May be involved in keratane sulfate biosynthesis. Transfers N-acetylgalactosamine on to keratan sulfate-related glycans. May play a role in preventing cells from migrating out of the original tissues and invading surrounding tissues (401 aa)
GALNT14UDP-N-acetyl-alpha-D-galactosamine-polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14) (552 aa)
GALNT10UDP-N-acetyl-alpha-D-galactosamine-polypeptide N-acetylgalactosaminyltransferase 10 (GalNAc-T10) (603 aa)
MUC17mucin 17, cell surface associated; Probably plays a role in maintaining homeostasis on mucosal surfaces (4493 aa)
C1GALT1C1C1GALT1-specific chaperone 1; Probable chaperone required for the generation of 1 O- glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins. Probably acts as a specific molecular chaperone assisting the folding/stability of core 1 beta-3-galactosyltransferase (C1GALT1) (318 aa)
B3GNT2UDP-GlcNAc-betaGal beta-1,3-N-acetylglucosaminyltransferase 2; Catalyzes the initiation and elongation of poly-N- acetyllactosamine chains (397 aa)
MUCL1mucin-like 1; May play a role as marker for the diagnosis of metastatic breast cancer (90 aa)
MUC13mucin 13, cell surface associated; Epithelial and hemopoietic transmembrane mucin that may play a role in cell signaling (511 aa)
B3GNT8UDP-GlcNAc-betaGal beta-1,3-N-acetylglucosaminyltransferase 8; Beta-1,3-N-acetylglucosaminyltransferase that plays a role in the elongation of specific branch structures of multiantennary N-glycans. Has strong activity towards tetraantennary N-glycans and 2,6 triantennary glycans (397 aa)
GALNT11UDP-N-acetyl-alpha-D-galactosamine-polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11); Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor. Displays the same enzyme activity toward Muc1, Muc4.1, and EA2 than GALNT1. Does not appear to be involved in glycosylation of erythropoietin (608 aa)
B3GNT5UDP-GlcNAc-betaGal beta-1,3-N-acetylglucosaminyltransferase 5; Beta-1,3-N-acetylglucosaminyltransferase that plays a key role in the synthesis of lacto- or neolacto-series carbohydrate chains on glycolipids, notably by participating in biosynthesis of HNK-1 and Lewis X carbohydrate structures. Has strong activity toward lactosylceramide (LacCer) and neolactotetraosylceramide (nLc(4)Cer; paragloboside), resulting in the synthesis of Lc(3)Cer and neolactopentaosylceramide (nLc(5)Cer), respectively. Probably plays a central role in regulating neolacto-series glycolipid synthesis during em [...] (378 aa)
B3GNT4UDP-GlcNAc-betaGal beta-1,3-N-acetylglucosaminyltransferase 4; Has a beta-1,3-N-acetylglucosaminyltransferase activity for type 2 oligosaccharides (378 aa)
B3GNT3UDP-GlcNAc-betaGal beta-1,3-N-acetylglucosaminyltransferase 3; Has a beta-1,3-N-acetylglucosaminyltransferase activity for type 2 oligosaccharides (372 aa)
MUC3Amucin 3A, cell surface associated; Major glycoprotein component of a variety of mucus gels. Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces (By similarity) (876 aa)
GALNTL2UDP-N-acetyl-alpha-D-galactosamine-polypeptide N-acetylgalactosaminyltransferase-like 2; Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor. Although it displays a much weaker activity toward all substrates tested compared to GALNT2, it is able to transfer up to seven GalNAc residues to the Muc5AC peptide, suggesting that it can fill vicinal Thr/Ser residues in cooperation with other GALNT proteins. Prefers Muc1a as substrate (639 aa)
GALNT6UDP-N-acetyl-alpha-D-galactosamine-polypeptide N-acetylgalactosaminyltransferase 6 (GalNAc-T6); Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor. May participate in synthesis of oncofetal fibronectin. Has activity toward Muc1a, Muc2, EA2 and fibronectin peptides (622 aa)
GALNT2UDP-N-acetyl-alpha-D-galactosamine-polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2); Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor. Has a broad spectrum of substrates for peptides such as EA2, Muc5AC, Muc1a, Muc1b. Probably involved in O-linked glycosylation of the immunoglobulin A1 (IgA1) hinge region (571 aa)
GALNT12UDP-N-acetyl-alpha-D-galactosamine-polypeptide N-acetylgalactosaminyltransferase 12 (GalNAc-T12); Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor. Has activity toward non-glycosylated peptides such as Muc5AC, Muc1a and EA2, and no detectable activity with Muc2 and Muc7. Displays enzymatic activity toward the Gal-NAc- Muc5AC glycopeptide, but no detectable activity to mono-GalNAc- glycosylated Muc1a, Muc2, Muc7 and EA2. May play an important role in the [...] (581 aa)
MUC21mucin 21, cell surface associated (566 aa)
GCNT1glucosaminyl (N-acetyl) transferase 1, core 2; Forms critical branches in O-glycans (428 aa)
GALNT3UDP-N-acetyl-alpha-D-galactosamine-polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3); Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor. Has activity toward HIV envelope glycoprotein gp120, EA2, Muc2 and Muc5. Probably glycosylates fibronectin in vivo. Glycosylates FGF23. Plays a central role in phosphate homeostasis (633 aa)
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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