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EHHADH | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase (723 aa) | |||
LRFN3 | leucine rich repeat and fibronectin type III domain containing 3; Cell adhesion molecule that mediates homophilic cell- cell adhesion in a Ca(2+)-independent manner. Promotes neurite outgrowth in hippocampal neurons (By similarity) (628 aa) | |||
PPP2R3C | protein phosphatase 2, regulatory subunit B’’, gamma (453 aa) | |||
CNOT6L | CCR4-NOT transcription complex, subunit 6-like; Has 3’-5’ poly(A) exoribonuclease activity for synthetic poly(A) RNA substrate. Catalytic component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. May be involved in the deadenylation-dependent degradation of mRNAs through the 3 [...] (555 aa) | |||
GFOD2 | glucose-fructose oxidoreductase domain containing 2; Promotes matrix assembly (By similarity) (385 aa) | |||
NR2C2 | nuclear receptor subfamily 2, group C, member 2; Orphan nuclear receptor that can act as a repressor or activator of transcription. An important repressor of nuclear recptor signaling pathways such as retinoic acid receptor, retinoid X, vitamin D3 receptor, thyroid hormone receptor and estrogen receptor pathways. May regulate gene expression during the late phase of spermatogenesis. Together with NR2C1, forms the core of the DRED (direct repeat erythroid-definitive) complex that represses embryonic and fetal globin transcription including that of GATA1. Binds to hormone response elemen [...] (615 aa) | |||
DMTF1 | cyclin D binding myb-like transcription factor 1 (760 aa) | |||
FOXN2 | forkhead box N2; Binds to the purine-rich region in HTLV-I LTR (431 aa) | |||
LRFN2 | leucine rich repeat and fibronectin type III domain containing 2; Promotes neurite outgrowth in hippocampal neurons. Enhances the cell surface expression of 2 NMDA receptor subunits GRIN1 and GRIN2A. May play a role in redistributing DLG4 to the cell periphery (By similarity) (789 aa) | |||
HIBCH | 3-hydroxyisobutyryl-CoA hydrolase; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite. Has high activity toward isobutyryl-CoA. Could be an isobutyryl-CoA dehydrogenase that functions in valine catabolism. Also hydrolyzes 3-hydroxypropanoyl-CoA (386 aa) | |||
FOXJ3 | forkhead box J3 (622 aa) | |||
TLR1 | toll-like receptor 1; Participates in the innate immune response to microbial agents. Specifically recognizes diacylated and triacylated lipopeptides. Cooperates with TLR2 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity) (786 aa) | |||
LRIG2 | leucine-rich repeats and immunoglobulin-like domains 2 (1065 aa) | |||
LRRC8C | leucine rich repeat containing 8 family, member C; May play a role in adipogenesis (By similarity) (803 aa) | |||
TCTE1 | t-complex-associated-testis-expressed 1 (501 aa) | |||
ABHD13 | abhydrolase domain containing 13 (337 aa) | |||
UBQLN1 | ubiquilin 1; Links CD47 to the cytoskeleton. Promotes the surface expression of GABA-A receptors (By similarity). Promotes the accumulation of uncleaved PSEN1 and PSEN2 by stimulating their biosynthesis. Has no effect on PSEN1 and PSEN2 degradation (589 aa) | |||
ECI2 | enoyl-CoA delta isomerase 2 (394 aa) | |||
HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit; Bifunctional subunit (763 aa) | |||
LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 (763 aa) | |||
ADHFE1 | alcohol dehydrogenase, iron containing, 1; Catalyzes the cofactor-independent reversible oxidation of gamma-hydroxybutyrate (GHB) to succinic semialdehyde (SSA) coupled to reduction of 2-ketoglutarate (2-KG) to D-2- hydroxyglutarate (D-2-HG). D,L-3-hydroxyisobutyrate and L-3- hydroxybutyrate (L-3-OHB) are also substrates for HOT with 10-fold lower activities (467 aa) |