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DHODH | dihydroorotate dehydrogenase (quinone); Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (395 aa) | |||
BLNK | B-cell linker; Functions as a central linker protein, downstream of the B-cell receptor (BCR), bridging the SYK kinase to a multitude of signaling pathways and regulating biological outcomes of B-cell function and development. Plays a role in the activation of ERK/EPHB2, MAP kinase p38 and JNK. Modulates AP1 activation. Important for the activation of NF-kappa-B and NFAT. Plays an important role in BCR-mediated PLCG1 and PLCG2 activation and Ca(2+) mobilization and is required for trafficking of the BCR to late endosomes. However, does not seem to be required for pre-BCR- mediated acti [...] (456 aa) | |||
SFXN3 | sideroflexin 3; Potential iron transporter (325 aa) | |||
PTCD3 | pentatricopeptide repeat domain 3; Mitochondrial RNA-binding protein that has a role in mitochondrial translation (689 aa) | |||
S100A11 | S100 calcium binding protein A11; Facilitates the differentiation and the cornification of keratinocytes (105 aa) | |||
HTR5A | 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled; This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins (357 aa) | |||
TMEM79 | transmembrane protein 79 (394 aa) | |||
STT3B | STT3, subunit of the oligosaccharyltransferase complex, homolog B (S. cerevisiae); Catalytic subunit of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). STT3B is present in a small subs [...] (826 aa) | |||
CCR1 | chemokine (C-C motif) receptor 1; Receptor for a C-C type chemokine. Binds to MIP-1-alpha, MIP-1-delta, RANTES, and MCP-3 and, less efficiently, to MIP-1- beta or MCP-1 and subsequently transduces a signal by increasing the intracellular calcium ions level. Responsible for affecting stem cell proliferation (355 aa) | |||
NUDCD2 | NudC domain containing 2; May regulate the LIS1/dynein pathway by stabilizing LIS1 with Hsp90 chaperone (157 aa) | |||
CD2BP2 | CD2 (cytoplasmic tail) binding protein 2; Involved in pre-mRNA splicing as component of the U5 snRNP complex that is involved in spliceosome assembly (341 aa) | |||
MRP63 | mitochondrial ribosomal protein 63 (102 aa) | |||
LACC1 | laccase (multicopper oxidoreductase) domain containing 1 (430 aa) | |||
CLN8 | ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation); Could play a role in cell proliferation during neuronal differentiation and in protection against cell death (286 aa) | |||
MRPL30 | mitochondrial ribosomal protein L30 (161 aa) | |||
HNRNPF | heterogeneous nuclear ribonucleoprotein F; Component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Plays a role in the regulation of alternative splicing events. Binds G-rich sequences in pre-mRNAs and keeps target RNA in an unfolded state (415 aa) | |||
LAGE3 | L antigen family, member 3 (143 aa) | |||
SGOL2 | shugoshin-like 2 (S. pombe); Cooperates with PPP2CA to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I. Has a crucial role in protecting REC8 at centromeres from cleavage by separase. During meiosis, protects centromeric cohesion complexes until metaphase II/anaphase II transition, preventing premature release of meiosis-specific REC8 cohesin complexes from anaphase I centromeres. Is thus essential for an accurate gametogenesis. May act by targeting PPP2CA to centromeres, thus leading to cohesin dephosphorylation (By similarity). Ess [...] (1265 aa) | |||
MRPL9 | mitochondrial ribosomal protein L9 (267 aa) | |||
SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein (623 aa) | |||
MRPL41 | mitochondrial ribosomal protein L41; Component of the mitochondrial ribosome large subunit. Also involved in apoptosis and cell cycle. Enhances p53/TP53 stability, thereby contributing to p53/TP53-induced apoptosis in response to growth-inhibitory condition. Enhances p53/TP53 translocation to the mitochondria. Has the ability to arrest the cell cycle at the G1 phase, possibly by stabilizing the CDKN1A and CDKN1B (p27Kip1) proteins (137 aa) | |||
PLP2 | proteolipid protein 2 (colonic epithelium-enriched); May play a role in cell differentiation in the intestinal epithelium (152 aa) | |||
BCAP31 | B-cell receptor-associated protein 31; May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi. May be involved in CASP8-mediated apoptosis (313 aa) | |||
SLC12A4 | solute carrier family 12 (potassium/chloride transporters), member 4 (1087 aa) | |||
ILF3 | interleukin enhancer binding factor 3, 90kDa (898 aa) | |||
CCDC155 | coiled-coil domain containing 155; May be involved in meiotic chromosome dynamics and homolog pairing (By similarity) (562 aa) |