node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CORO1A | UBC | ENSP00000219150 | ENSP00000344818 | coronin, actin binding protein, 1A; May be a crucial component of the cytoskeleton of highly motile cells, functioning both in the invagination of large pieces of plasma membrane, as well as in forming protrusions of the plasma membrane involved in cell locomotion. In mycobacteria- infected cells, its retention on the phagosomal membrane prevents fusion between phagosomes and lysosomes | ubiquitin C | 0.923 |
CORO1B | CORO1C | ENSP00000340211 | ENSP00000261401 | coronin, actin binding protein, 1B; Regulates leading edge dynamics and cell motility in fibroblasts. May be involved in cytokinesis and signal transduction (By similarity) | coronin, actin binding protein, 1C; May be involved in cytokinesis, motility, and signal transduction (By similarity) | 0.544 |
CORO1B | UBC | ENSP00000340211 | ENSP00000344818 | coronin, actin binding protein, 1B; Regulates leading edge dynamics and cell motility in fibroblasts. May be involved in cytokinesis and signal transduction (By similarity) | ubiquitin C | 0.890 |
CORO1C | CORO1B | ENSP00000261401 | ENSP00000340211 | coronin, actin binding protein, 1C; May be involved in cytokinesis, motility, and signal transduction (By similarity) | coronin, actin binding protein, 1B; Regulates leading edge dynamics and cell motility in fibroblasts. May be involved in cytokinesis and signal transduction (By similarity) | 0.544 |
CORO1C | UBC | ENSP00000261401 | ENSP00000344818 | coronin, actin binding protein, 1C; May be involved in cytokinesis, motility, and signal transduction (By similarity) | ubiquitin C | 0.919 |
CORO6 | UBC | ENSP00000344562 | ENSP00000344818 | coronin 6 | ubiquitin C | 0.487 |
PHKA1 | PHKB | ENSP00000362643 | ENSP00000313504 | phosphorylase kinase, alpha 1 (muscle); Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The alpha chain may bind calmodulin | phosphorylase kinase, beta; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The beta chain acts as a regulatory unit and modulates the activity of the holoenzyme in response to phosphorylation | 0.541 |
PHKA1 | PHKG1 | ENSP00000362643 | ENSP00000297373 | phosphorylase kinase, alpha 1 (muscle); Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The alpha chain may bind calmodulin | phosphorylase kinase, gamma 1 (muscle); Catalytic subunit of the phosphorylase b kinase (PHK), which mediates the neural and hormonal regulation of glycogen breakdown (glycogenolysis) by phosphorylating and thereby activating glycogen phosphorylase. In vitro, phosphorylates PYGM, TNNI3, MAPT/TAU, GAP43 and NRGN/RC3 (By similarity) | 0.867 |
PHKA1 | PHKG2 | ENSP00000362643 | ENSP00000455607 | phosphorylase kinase, alpha 1 (muscle); Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The alpha chain may bind calmodulin | phosphorylase kinase, gamma 2 (testis); Catalytic subunit of the phosphorylase b kinase (PHK), which mediates the neural and hormonal regulation of glycogen breakdown (glycogenolysis) by phosphorylating and thereby activating glycogen phosphorylase. May regulate glycogeneolysis in the testis. In vitro, phosphorylates PYGM (By similarity) | 0.933 |
PHKA1 | UBC | ENSP00000362643 | ENSP00000344818 | phosphorylase kinase, alpha 1 (muscle); Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The alpha chain may bind calmodulin | ubiquitin C | 0.483 |
PHKA2 | PHKB | ENSP00000369274 | ENSP00000313504 | phosphorylase kinase, alpha 2 (liver); Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The alpha chain may bind calmodulin | phosphorylase kinase, beta; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The beta chain acts as a regulatory unit and modulates the activity of the holoenzyme in response to phosphorylation | 0.953 |
PHKA2 | PHKG1 | ENSP00000369274 | ENSP00000297373 | phosphorylase kinase, alpha 2 (liver); Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The alpha chain may bind calmodulin | phosphorylase kinase, gamma 1 (muscle); Catalytic subunit of the phosphorylase b kinase (PHK), which mediates the neural and hormonal regulation of glycogen breakdown (glycogenolysis) by phosphorylating and thereby activating glycogen phosphorylase. In vitro, phosphorylates PYGM, TNNI3, MAPT/TAU, GAP43 and NRGN/RC3 (By similarity) | 0.930 |
PHKA2 | PHKG2 | ENSP00000369274 | ENSP00000455607 | phosphorylase kinase, alpha 2 (liver); Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The alpha chain may bind calmodulin | phosphorylase kinase, gamma 2 (testis); Catalytic subunit of the phosphorylase b kinase (PHK), which mediates the neural and hormonal regulation of glycogen breakdown (glycogenolysis) by phosphorylating and thereby activating glycogen phosphorylase. May regulate glycogeneolysis in the testis. In vitro, phosphorylates PYGM (By similarity) | 0.994 |
PHKB | PHKA1 | ENSP00000313504 | ENSP00000362643 | phosphorylase kinase, beta; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The beta chain acts as a regulatory unit and modulates the activity of the holoenzyme in response to phosphorylation | phosphorylase kinase, alpha 1 (muscle); Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The alpha chain may bind calmodulin | 0.541 |
PHKB | PHKA2 | ENSP00000313504 | ENSP00000369274 | phosphorylase kinase, beta; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The beta chain acts as a regulatory unit and modulates the activity of the holoenzyme in response to phosphorylation | phosphorylase kinase, alpha 2 (liver); Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The alpha chain may bind calmodulin | 0.953 |
PHKB | PHKG1 | ENSP00000313504 | ENSP00000297373 | phosphorylase kinase, beta; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The beta chain acts as a regulatory unit and modulates the activity of the holoenzyme in response to phosphorylation | phosphorylase kinase, gamma 1 (muscle); Catalytic subunit of the phosphorylase b kinase (PHK), which mediates the neural and hormonal regulation of glycogen breakdown (glycogenolysis) by phosphorylating and thereby activating glycogen phosphorylase. In vitro, phosphorylates PYGM, TNNI3, MAPT/TAU, GAP43 and NRGN/RC3 (By similarity) | 0.992 |
PHKB | PHKG2 | ENSP00000313504 | ENSP00000455607 | phosphorylase kinase, beta; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The beta chain acts as a regulatory unit and modulates the activity of the holoenzyme in response to phosphorylation | phosphorylase kinase, gamma 2 (testis); Catalytic subunit of the phosphorylase b kinase (PHK), which mediates the neural and hormonal regulation of glycogen breakdown (glycogenolysis) by phosphorylating and thereby activating glycogen phosphorylase. May regulate glycogeneolysis in the testis. In vitro, phosphorylates PYGM (By similarity) | 0.994 |
PHKB | RILPL1 | ENSP00000313504 | ENSP00000366070 | phosphorylase kinase, beta; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The beta chain acts as a regulatory unit and modulates the activity of the holoenzyme in response to phosphorylation | Rab interacting lysosomal protein-like 1; Neuroprotective protein, which acts by sequestring GAPDH in the cytosol and prevent the apoptotic function of GAPDH in the nucleus. Competes with SIAH1 for binding GAPDH (By similarity). Does not regulate lysosomal morphology and distribution | 0.726 |
PHKG1 | PHKA1 | ENSP00000297373 | ENSP00000362643 | phosphorylase kinase, gamma 1 (muscle); Catalytic subunit of the phosphorylase b kinase (PHK), which mediates the neural and hormonal regulation of glycogen breakdown (glycogenolysis) by phosphorylating and thereby activating glycogen phosphorylase. In vitro, phosphorylates PYGM, TNNI3, MAPT/TAU, GAP43 and NRGN/RC3 (By similarity) | phosphorylase kinase, alpha 1 (muscle); Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The alpha chain may bind calmodulin | 0.867 |
PHKG1 | PHKA2 | ENSP00000297373 | ENSP00000369274 | phosphorylase kinase, gamma 1 (muscle); Catalytic subunit of the phosphorylase b kinase (PHK), which mediates the neural and hormonal regulation of glycogen breakdown (glycogenolysis) by phosphorylating and thereby activating glycogen phosphorylase. In vitro, phosphorylates PYGM, TNNI3, MAPT/TAU, GAP43 and NRGN/RC3 (By similarity) | phosphorylase kinase, alpha 2 (liver); Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The alpha chain may bind calmodulin | 0.930 |