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PSMB2 PSMB2 PSMD2 PSMD2 PSMD4 PSMD4 RPS27A RPS27A RPS28 RPS28 RPS27L RPS27L UBA52 UBA52 UBD UBD MRPS7 MRPS7 HACE1 HACE1 RPS5 RPS5 RPS7 RPS7 RPS4Y1 RPS4Y1 RPS3A RPS3A RPS9 RPS9 RPS4Y2 RPS4Y2 RPS29 RPS29 RPS4X RPS4X RPSA RPSA RPS6 RPS6 RPSAP58 RPSAP58 RPS16 RPS16 RPS13 RPS13 RPS15 RPS15 ENSG00000260836 ENSG00000260836 RPS27 RPS27
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
RPS5ribosomal protein S5 (204 aa)
MRPS7mitochondrial ribosomal protein S7 (242 aa)
RPS4Y1ribosomal protein S4, Y-linked 1 (263 aa)
RPS16ribosomal protein S16 (146 aa)
HACE1HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 (909 aa)
RPS27Aribosomal protein S27a (156 aa)
RPS4Y2ribosomal protein S4, Y-linked 2 (263 aa)
RPS9ribosomal protein S9 (194 aa)
PSMD2proteasome (prosome, macropain) 26S subunit, non-ATPase, 2; Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins (908 aa)
RPS27Lribosomal protein S27-like (84 aa)
RPS7ribosomal protein S7; Required for rRNA maturation (194 aa)
RPS3Aribosomal protein S3A; May play a role during erythropoiesis through regulation of transcription factor DDIT3 (By similarity) (264 aa)
RPSAribosomal protein SA; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Also acts as a receptor for several other ligands, including the pathogenic prion protein, viruses, and bacteria. A [...] (295 aa)
RPSAP58ribosomal protein SA pseudogene 58; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Also acts as a receptor for several other ligands, including the pathogenic prion protein, viruses, a [...] (295 aa)
RPS27ribosomal protein S27 (84 aa)
PSMD4proteasome (prosome, macropain) 26S subunit, non-ATPase, 4; Binds and presumably selects ubiquitin-conjugates for destruction. Displays selectivity for longer polyubiquitin chains. Modulates intestinal fluid secretion (377 aa)
PSMB2proteasome (prosome, macropain) subunit, beta type, 2; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit has a trypsin-like activity (201 aa)
RPS4Xribosomal protein S4, X-linked (263 aa)
UBDubiquitin D (165 aa)
RPS6ribosomal protein S6; May play an important role in controlling cell growth and proliferation through the selective translation of particular classes of mRNA (249 aa)
RPS29ribosomal protein S29 (67 aa)
UBA52ubiquitin A-52 residue ribosomal protein fusion product 1 (128 aa)
RPS13ribosomal protein S13 (151 aa)
ENSG00000260836Uncharacterized protein (293 aa)
RPS15ribosomal protein S15 (145 aa)
RPS28ribosomal protein S28 (69 aa)
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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