Export your current network:
... as a bitmap image:
file format is 'PNG': portable network graphic
... as a high-resolution bitmap:
same PNG format, but resolution at 400 dpi
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as simple tabular text output:
TSV: tab separated values - can be opened in Excel
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and annotated functions of the network proteins
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CBWD5 | UBC | ENSP00000366612 | ENSP00000344818 | COBW domain containing 5 | ubiquitin C | 0.721 |
| GTF2E1 | UBC | ENSP00000283875 | ENSP00000344818 | general transcription factor IIE, polypeptide 1, alpha 56kDa; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase | ubiquitin C | 0.626 |
| METAP1 | METAP2 | ENSP00000296411 | ENSP00000325312 | methionyl aminopeptidase 1; Removes the N-terminal methionine from nascent proteins. Required for normal progression through the cell cycle | methionyl aminopeptidase 2; Removes the N-terminal methionine from nascent proteins. The catalytic activity of human METAP2 toward Met-Val peptides is consistently two orders of magnitude higher than that of METAP1, suggesting that it is responsible for processing proteins containing N-terminal Met-Val and Met-Thr sequences in vivo | 0.971 |
| METAP1 | UBC | ENSP00000296411 | ENSP00000344818 | methionyl aminopeptidase 1; Removes the N-terminal methionine from nascent proteins. Required for normal progression through the cell cycle | ubiquitin C | 0.707 |
| METAP1D | METAP2 | ENSP00000315152 | ENSP00000325312 | methionyl aminopeptidase type 1D (mitochondrial); Removes the N-terminal methionine from nascent proteins (By similarity). May play a role in colon tumorigenesis | methionyl aminopeptidase 2; Removes the N-terminal methionine from nascent proteins. The catalytic activity of human METAP2 toward Met-Val peptides is consistently two orders of magnitude higher than that of METAP1, suggesting that it is responsible for processing proteins containing N-terminal Met-Val and Met-Thr sequences in vivo | 0.923 |
| METAP2 | METAP1 | ENSP00000325312 | ENSP00000296411 | methionyl aminopeptidase 2; Removes the N-terminal methionine from nascent proteins. The catalytic activity of human METAP2 toward Met-Val peptides is consistently two orders of magnitude higher than that of METAP1, suggesting that it is responsible for processing proteins containing N-terminal Met-Val and Met-Thr sequences in vivo | methionyl aminopeptidase 1; Removes the N-terminal methionine from nascent proteins. Required for normal progression through the cell cycle | 0.971 |
| METAP2 | METAP1D | ENSP00000325312 | ENSP00000315152 | methionyl aminopeptidase 2; Removes the N-terminal methionine from nascent proteins. The catalytic activity of human METAP2 toward Met-Val peptides is consistently two orders of magnitude higher than that of METAP1, suggesting that it is responsible for processing proteins containing N-terminal Met-Val and Met-Thr sequences in vivo | methionyl aminopeptidase type 1D (mitochondrial); Removes the N-terminal methionine from nascent proteins (By similarity). May play a role in colon tumorigenesis | 0.923 |
| METAP2 | UBC | ENSP00000325312 | ENSP00000344818 | methionyl aminopeptidase 2; Removes the N-terminal methionine from nascent proteins. The catalytic activity of human METAP2 toward Met-Val peptides is consistently two orders of magnitude higher than that of METAP1, suggesting that it is responsible for processing proteins containing N-terminal Met-Val and Met-Thr sequences in vivo | ubiquitin C | 0.923 |
| PA2G4 | UBC | ENSP00000302886 | ENSP00000344818 | proliferation-associated 2G4, 38kDa; May play a role in a ERBB3-regulated signal transduction pathway. Seems be involved in growth regulation. Acts a corepressor of the androgen receptor (AR) and is regulated by the ERBB3 ligand neuregulin-1/heregulin (HRG). Inhibits transcription of some E2F1-regulated promoters, probably by recruiting histone acetylase (HAT) activity. Binds RNA. Associates with 28S, 18S and 5.8S mature rRNAs, several rRNA precursors and probably U3 small nucleolar RNA. May be involved in regulation of intermediate and late steps of rRNA processing. May be involved in [...] | ubiquitin C | 0.983 |
| TXNDC9 | UBC | ENSP00000264255 | ENSP00000344818 | thioredoxin domain containing 9; Significantly diminishes the chaperonin TCP1 complex ATPase activity, thus negatively impacts protein folding, including that of actin or tubulin | ubiquitin C | 0.762 |
| UBC | CBWD5 | ENSP00000344818 | ENSP00000366612 | ubiquitin C | COBW domain containing 5 | 0.721 |
| UBC | GTF2E1 | ENSP00000344818 | ENSP00000283875 | ubiquitin C | general transcription factor IIE, polypeptide 1, alpha 56kDa; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase | 0.626 |
| UBC | METAP1 | ENSP00000344818 | ENSP00000296411 | ubiquitin C | methionyl aminopeptidase 1; Removes the N-terminal methionine from nascent proteins. Required for normal progression through the cell cycle | 0.707 |
| UBC | METAP2 | ENSP00000344818 | ENSP00000325312 | ubiquitin C | methionyl aminopeptidase 2; Removes the N-terminal methionine from nascent proteins. The catalytic activity of human METAP2 toward Met-Val peptides is consistently two orders of magnitude higher than that of METAP1, suggesting that it is responsible for processing proteins containing N-terminal Met-Val and Met-Thr sequences in vivo | 0.923 |
| UBC | PA2G4 | ENSP00000344818 | ENSP00000302886 | ubiquitin C | proliferation-associated 2G4, 38kDa; May play a role in a ERBB3-regulated signal transduction pathway. Seems be involved in growth regulation. Acts a corepressor of the androgen receptor (AR) and is regulated by the ERBB3 ligand neuregulin-1/heregulin (HRG). Inhibits transcription of some E2F1-regulated promoters, probably by recruiting histone acetylase (HAT) activity. Binds RNA. Associates with 28S, 18S and 5.8S mature rRNAs, several rRNA precursors and probably U3 small nucleolar RNA. May be involved in regulation of intermediate and late steps of rRNA processing. May be involved in [...] | 0.983 |
| UBC | TXNDC9 | ENSP00000344818 | ENSP00000264255 | ubiquitin C | thioredoxin domain containing 9; Significantly diminishes the chaperonin TCP1 complex ATPase activity, thus negatively impacts protein folding, including that of actin or tubulin | 0.762 |
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