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AQP2 | aquaporin 2 (collecting duct); Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient (271 aa) | |||
SLC32A1 | solute carrier family 32 (GABA vesicular transporter), member 1; Involved in the uptake of GABA and glycine into the synaptic vesicles (525 aa) | |||
SLC38A7 | solute carrier family 38, member 7; Mediates sodium-dependent transport of amino acids, preferentially L-glutamine (By similarity) (462 aa) | |||
AQP8 | aquaporin 8; Forms a water-specific channel; mercury-sensitive. Not permeable to glycerol or urea (261 aa) | |||
MOSPD3 | motile sperm domain containing 3 (235 aa) | |||
SLC38A2 | solute carrier family 38, member 2; Functions as a sodium-dependent amino acid transporter. Mediates the saturable, pH-sensitive and electrogenic cotransport of neutral amino acids and sodium ions with a stoichiometry of 1-1. May function in the transport of amino acids at the blood- brain barrier and in the supply of maternal nutrients to the fetus through the placenta (506 aa) | |||
MIP | major intrinsic protein of lens fiber; Water channel. May be responsible for regulating the osmolarity of the lens. Interactions between homotetramers from adjoining membranes may stabilize cell junctions in the eye lens core (By similarity) (263 aa) | |||
USP2 | ubiquitin specific peptidase 2; Hydrolase that deubiquitinates polyubiquitinated target proteins such as MDM2, MDM4 and CCND1. Isoform 1 and isoform 4 possess both ubiquitin-specific peptidase and isopeptidase activities. Deubiquitinates MDM2 without reversing MDM2-mediated p53/TP53 ubiquitination and thus indirectly promotes p53/TP53 degradation and limits p53 activity. Has no deubiquitinase activity against p53/TP53. Prevents MDM2-mediated degradation of MDM4. Plays a role in the G1/S cell-cycle progression in normal and cancer cells. Plays a role in the regulation of myogenic differ [...] (605 aa) | |||
SLC38A4 | solute carrier family 38, member 4; Sodium-dependent amino acid transporter. Mediates electrogenic symport of neutral amino acids and sodium ions. Has a broad specificity, with a preference for Ala, followed by His, Cys, Asn, Ser, Gly, Val, Thr, Gln and Met. May mediate sodium- independent transport of cationic amino acids, such as Arg and Lys. Amino acid uptake is pH-dependent, with low transport activities at pH 6.5, intermediate at pH 7.0 and highest between pH 7.5 and 8.5 (547 aa) | |||
CCNB3 | cyclin B3; Cyclins are positive regulatory subunits of the cyclin- dependent kinases (CDKs), and thereby play an essential role in the control of the cell cycle, notably via their destruction during cell division. Its tissue specificity suggest that it may be required during early meiotic prophase I (1395 aa) | |||
AQP5 | aquaporin 5; Forms a water-specific channel. Implicated in the generation of saliva, tears, and pulmonary secretions (265 aa) | |||
SLC38A8 | solute carrier family 38, member 8; Putative sodium-dependent amino acid/proton antiporter (By similarity) (435 aa) | |||
TXNDC2 | thioredoxin domain containing 2 (spermatozoa); Probably plays a regulatory role in sperm development. May participate in regulation of fibrous sheath (FS) assembly by supporting the formation of disulfide bonds during sperm tail morphogenesis. May also be required to rectify incorrect disulfide pairing and generate suitable pairs between the FS constituents. Can reduce disulfide bonds in vitro in the presence of NADP and thioredoxin reductase (553 aa) | |||
AQP1 | aquaporin 1 (Colton blood group); Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient (269 aa) | |||
SLC38A5 | solute carrier family 38, member 5; Functions as a sodium-dependent amino acid transporter which countertransport protons. Mediates the saturable, pH- sensitive, and electrogenic cotransport of several neutral amino acids including glycine, asparagine, alanine, serine, glutamine and histidine with sodium (472 aa) | |||
AQP6 | aquaporin 6, kidney specific; Forms a water-specific channel that participates in distinct physiological functions such as glomerular filtration, tubular endocytosis and acid-base metabolism (By similarity) (282 aa) | |||
UBL4B | ubiquitin-like 4B (174 aa) | |||
ZFAND4 | zinc finger, AN1-type domain 4 (727 aa) | |||
TXNDC8 | thioredoxin domain containing 8 (spermatozoa); May be required for post-translational modifications of proteins required for acrosomal biogenesis. May act by reducing disulfide bonds within the sperm (115 aa) | |||
SLC38A10 | solute carrier family 38, member 10; Putative sodium-dependent amino acid/proton antiporter (By similarity) (1119 aa) | |||
SLC36A3 | solute carrier family 36 (proton/amino acid symporter), member 3 (511 aa) | |||
UBQLNL | ubiquilin-like (475 aa) | |||
AQP4 | aquaporin 4; Forms a water-specific channel. Osmoreceptor which regulates body water balance and mediates water flow within the central nervous system (323 aa) | |||
ENSG00000250424 | Uncharacterized protein (446 aa) | |||
USP50 | ubiquitin specific peptidase 50; Has no peptidase activity (334 aa) | |||
UBBP4 | ubiquitin B pseudogene 4 (229 aa) |