node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACOT9 | DAB2 | ENSP00000368605 | ENSP00000313391 | acyl-CoA thioesterase 9; Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. Active on long chain acyl-CoAs | disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila); Adapter protein that functions as clathrin-associated sorting protein (CLASP) required for clathrin-mediated endocytosis of selected cargo proteins. Can bind and assemble clathrin, and binds simultaneously to phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) and cargos containg non-phosphorylated NPXY internalization motifs, such as the LDL receptor, to recruit them to clathrin-coated pits. Can function in clathrin-mediated endocytosis independently of the AP-2 complex. Involved in endocytosis of integrin beta-1; t [...] | 0.430 |
ACOT9 | GRSF1 | ENSP00000368605 | ENSP00000254799 | acyl-CoA thioesterase 9; Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. Active on long chain acyl-CoAs | G-rich RNA sequence binding factor 1; Binds RNAs containing the 14 base G-rich element | 0.481 |
ACOT9 | MINOS1 | ENSP00000368605 | ENSP00000325562 | acyl-CoA thioesterase 9; Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. Active on long chain acyl-CoAs | mitochondrial inner membrane organizing system 1; May play a role in mitochondrial architecture (By similarity) | 0.512 |
ACOT9 | MYO16 | ENSP00000368605 | ENSP00000349145 | acyl-CoA thioesterase 9; Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. Active on long chain acyl-CoAs | myosin XVI | 0.570 |
ACOT9 | UBC | ENSP00000368605 | ENSP00000344818 | acyl-CoA thioesterase 9; Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. Active on long chain acyl-CoAs | ubiquitin C | 0.800 |
C12orf10 | UBC | ENSP00000267103 | ENSP00000344818 | chromosome 12 open reading frame 10 | ubiquitin C | 0.686 |
DAB2 | ACOT9 | ENSP00000313391 | ENSP00000368605 | disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila); Adapter protein that functions as clathrin-associated sorting protein (CLASP) required for clathrin-mediated endocytosis of selected cargo proteins. Can bind and assemble clathrin, and binds simultaneously to phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) and cargos containg non-phosphorylated NPXY internalization motifs, such as the LDL receptor, to recruit them to clathrin-coated pits. Can function in clathrin-mediated endocytosis independently of the AP-2 complex. Involved in endocytosis of integrin beta-1; t [...] | acyl-CoA thioesterase 9; Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. Active on long chain acyl-CoAs | 0.430 |
DAB2 | UBC | ENSP00000313391 | ENSP00000344818 | disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila); Adapter protein that functions as clathrin-associated sorting protein (CLASP) required for clathrin-mediated endocytosis of selected cargo proteins. Can bind and assemble clathrin, and binds simultaneously to phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) and cargos containg non-phosphorylated NPXY internalization motifs, such as the LDL receptor, to recruit them to clathrin-coated pits. Can function in clathrin-mediated endocytosis independently of the AP-2 complex. Involved in endocytosis of integrin beta-1; t [...] | ubiquitin C | 0.633 |
EGFR | UBC | ENSP00000275493 | ENSP00000344818 | epidermal growth factor receptor | ubiquitin C | 0.999 |
EHHADH | HADHA | ENSP00000231887 | ENSP00000370023 | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit; Bifunctional subunit | 0.972 |
EHHADH | HIBCH | ENSP00000231887 | ENSP00000352706 | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase | 3-hydroxyisobutyryl-CoA hydrolase; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite. Has high activity toward isobutyryl-CoA. Could be an isobutyryl-CoA dehydrogenase that functions in valine catabolism. Also hydrolyzes 3-hydroxypropanoyl-CoA | 0.952 |
GRSF1 | ACOT9 | ENSP00000254799 | ENSP00000368605 | G-rich RNA sequence binding factor 1; Binds RNAs containing the 14 base G-rich element | acyl-CoA thioesterase 9; Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. Active on long chain acyl-CoAs | 0.481 |
GRSF1 | HADHA | ENSP00000254799 | ENSP00000370023 | G-rich RNA sequence binding factor 1; Binds RNAs containing the 14 base G-rich element | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit; Bifunctional subunit | 0.503 |
GRSF1 | UBC | ENSP00000254799 | ENSP00000344818 | G-rich RNA sequence binding factor 1; Binds RNAs containing the 14 base G-rich element | ubiquitin C | 0.878 |
HADHA | EHHADH | ENSP00000370023 | ENSP00000231887 | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit; Bifunctional subunit | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase | 0.972 |
HADHA | GRSF1 | ENSP00000370023 | ENSP00000254799 | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit; Bifunctional subunit | G-rich RNA sequence binding factor 1; Binds RNAs containing the 14 base G-rich element | 0.503 |
HADHA | HIBCH | ENSP00000370023 | ENSP00000352706 | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit; Bifunctional subunit | 3-hydroxyisobutyryl-CoA hydrolase; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite. Has high activity toward isobutyryl-CoA. Could be an isobutyryl-CoA dehydrogenase that functions in valine catabolism. Also hydrolyzes 3-hydroxypropanoyl-CoA | 0.951 |
HADHA | UBC | ENSP00000370023 | ENSP00000344818 | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit; Bifunctional subunit | ubiquitin C | 0.943 |
HIBCH | EHHADH | ENSP00000352706 | ENSP00000231887 | 3-hydroxyisobutyryl-CoA hydrolase; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite. Has high activity toward isobutyryl-CoA. Could be an isobutyryl-CoA dehydrogenase that functions in valine catabolism. Also hydrolyzes 3-hydroxypropanoyl-CoA | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase | 0.952 |
HIBCH | HADHA | ENSP00000352706 | ENSP00000370023 | 3-hydroxyisobutyryl-CoA hydrolase; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite. Has high activity toward isobutyryl-CoA. Could be an isobutyryl-CoA dehydrogenase that functions in valine catabolism. Also hydrolyzes 3-hydroxypropanoyl-CoA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit; Bifunctional subunit | 0.951 |