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MOSPD3 | motile sperm domain containing 3 (235 aa) | |||
REEP6 | receptor accessory protein 6; May enhance the cell surface expression of odorant receptors (By similarity) (184 aa) | |||
RAB9B | RAB9B, member RAS oncogene family; Involved in the transport of proteins between the endosomes and the trans Golgi network (By similarity) (201 aa) | |||
LETMD1 | LETM1 domain containing 1 (360 aa) | |||
RAB7A | RAB7A, member RAS oncogene family; Key regulator in endo-lysosomal trafficking. Governs early-to-late endosomal maturation, microtubule minus-end as well as plus-end directed endosomal migration and positioning, and endosome-lysosome transport through different protein-protein interaction cascades. Plays a central role, not only in endosomal traffic, but also in many other cellular and physiological events, such as growth-factor-mediated cell signaling, nutrient- transportor mediated nutrient uptake, neurotrophin transport in the axons of neurons and lipid metabolism. Also involved in [...] (207 aa) | |||
GPR84 | G protein-coupled receptor 84; Receptor for medium-chain free fatty acid (FFA) with carbon chain lengths of C9 to C14. Capric acid (C10-0), undecanoic acid (C11-0) and lauric acid (C12-0) are the most potent agonists. Not activated by short-chain and long-chain saturated and unsaturated FFAs. Activation by medium-chain free fatty acid is coupled to a pertussis toxin sensitive G(i/o) protein pathway. May have important roles in processes from fatty acid metabolism to regulation of the immune system (396 aa) | |||
KIAA1715 | KIAA1715; May be involved in limb and central nervous system development (By similarity) (428 aa) | |||
RAB5A | RAB5A, member RAS oncogene family; Required for the fusion of plasma membranes and early endosomes. Contributes to the regulation of filopodia extension (215 aa) | |||
YIPF5 | Yip1 domain family, member 5; Plays a role in transport between endoplasmic reticulum and Golgi (257 aa) | |||
RAB41 | RAB41, member RAS oncogene family (221 aa) | |||
RAB6B | RAB6B, member RAS oncogene family; Seems to have a role in retrograde membrane traffic at the level of the Golgi complex. May function in retrograde transport in neuronal cells (208 aa) | |||
RAB8A | RAB8A, member RAS oncogene family; May be involved in vesicular trafficking and neurotransmitter release. Together with RAB11A, RAB3IP, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis. Together with MYO5B and RAB11A participates in epithelial cell polarization (207 aa) | |||
RAB8B | RAB8B, member RAS oncogene family; May be involved in vesicular trafficking and neurotransmitter release (By similarity). May participate in cell junction dynamics in Sertoli cells (By similarity) (207 aa) | |||
SCAMP4 | secretory carrier membrane protein 4; Probably involved in membrane protein trafficking (By similarity) (229 aa) | |||
ATP6V0A2 | ATPase, H+ transporting, lysosomal V0 subunit a2; Part of the proton channel of V-ATPases. Essential component of the endosomal pH-sensing machinery. May play a role in maintaining the Golgi functions, such as glycosylation maturation, by controlling the Golgi pH (856 aa) | |||
YIPF7 | Yip1 domain family, member 7 (280 aa) | |||
VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa; May play a role in vesicle trafficking (294 aa) | |||
RAB5C | RAB5C, member RAS oncogene family; Protein transport. Probably involved in vesicular traffic (By similarity) (216 aa) | |||
RAB5B | RAB5B, member RAS oncogene family; Protein transport. Probably involved in vesicular traffic (By similarity) (215 aa) | |||
RAB13 | RAB13, member RAS oncogene family; Could participate in polarized transport, in the assembly and/or the activity of tight junctions (203 aa) | |||
REEP5 | receptor accessory protein 5; May promote functional cell surface expression of olfactory receptors (189 aa) | |||
E2F6 | E2F transcription factor 6; Inhibitor of E2F-dependent transcription. Binds DNA cooperatively with DP proteins through the E2 recognition site, 5’-TTTC[CG]CGC-3’. Has a preference for the 5’-TTTCCCGC-3’ E2F recognition site. E2F6 lacks the transcriptional activation and pocket protein binding domains. Appears to regulate a subset of E2F-dependent genes whose products are required for entry into the cell cycle but not for normal cell cycle progression. May silence expression via the recruitment of a chromatin remodeling complex containing histone H3-K9 methyltransferase activity. Overex [...] (281 aa) | |||
BRD7 | bromodomain containing 7; Acts both as coactivator and as corepressor. May play a role in chromatin remodeling. Activator of the Wnt signaling pathway in a DVL1-dependent manner by negatively regulating the GSK3B phosphotransferase activity. Induces dephosphorylation of GSK3B at ’Tyr-216’. Down-regulates TRIM24-mediated activation of transcriptional activation by AR (By similarity). Transcriptional corepressor that down-regulates the expression of target genes. Binds to target promoters, leading to increased histone H3 acetylation at ’Lys-9’ (H3K9ac). Binds to the ESR1 promoter. Recrui [...] (652 aa) | |||
VAPB | VAMP (vesicle-associated membrane protein)-associated protein B and C; Participates in the endoplasmic reticulum unfolded protein response (UPR) by inducing ERN1/IRE1 activity. Involved in cellular calcium homeostasis regulation (243 aa) | |||
RAB9A | RAB9A, member RAS oncogene family; Involved in the transport of proteins between the endosomes and the trans Golgi network (201 aa) | |||
TMEM33 | transmembrane protein 33 (247 aa) |