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STRINGSTRING
IPO4 IPO4 UBB UBB UEVLD UEVLD UBC UBC LDHAL6B LDHAL6B LDHC LDHC CS CS LDHA LDHA LDHB LDHB MDH1 MDH1 AIFM2 AIFM2 TMEM4 TMEM4 MDH2 MDH2 LDHAL6A LDHAL6A MDH1B MDH1B NDUFAB1 NDUFAB1 SLC25A35 SLC25A35
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
NDUFAB1NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa; Carrier of the growing fatty acid chain in fatty acid biosynthesis in mitochondria. Accessory and non-catalytic subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain (By similarity) (156 aa)
LDHBlactate dehydrogenase B (334 aa)
LDHClactate dehydrogenase C; Possible role in sperm motility (332 aa)
LDHAL6Alactate dehydrogenase A-like 6A; Displays an lactate dehydrogenase activity. Significantly increases the transcriptional activity of JUN, when overexpressed (332 aa)
LDHAL6Blactate dehydrogenase A-like 6B (381 aa)
UBBubiquitin B (229 aa)
AIFM2apoptosis-inducing factor, mitochondrion-associated, 2; Oxidoreductase, which may play a role in mediating a p53/TP53-dependent apoptosis response. Probable oxidoreductase that acts as a caspase-independent mitochondrial effector of apoptotic cell death. Binds to DNA in a sequence-independent manner. May contribute to genotoxin-induced growth arrest (373 aa)
MDH2malate dehydrogenase 2, NAD (mitochondrial) (338 aa)
CScitrate synthase (466 aa)
UBCubiquitin C (685 aa)
IPO4importin 4; Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran- dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis re [...] (1081 aa)
MDH1Bmalate dehydrogenase 1B, NAD (soluble) (518 aa)
SLC25A35solute carrier family 25, member 35 (295 aa)
UEVLDUEV and lactate/malate dehyrogenase domains; Possible negative regulator of polyubiquitination (471 aa)
MDH1malate dehydrogenase 1, NAD (soluble) (352 aa)
LDHAlactate dehydrogenase A (361 aa)
TMEM4Uncharacterized protein (263 aa)
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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