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STRINGSTRING
UBOX5 UBOX5 UBE4A UBE4A UBE4B UBE4B RAD23A RAD23A RAD23B RAD23B PUF60 PUF60 PSMD4 PSMD4 UBQLNL UBQLNL PLEC PLEC MRPS9 MRPS9 FAU FAU RPS17L RPS17L RPS17 RPS17 PSMD2 PSMD2 UBA52 UBA52 RPS16 RPS16 ENSG00000260836 ENSG00000260836 RPS7 RPS7 RPS27A RPS27A RPS24 RPS24 RPS15 RPS15 HACE1 HACE1 RPS5 RPS5 RPS25 RPS25 RPS28 RPS28 RPS19 RPS19
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
RPS5ribosomal protein S5 (204 aa)
UBOX5U-box domain containing 5 (541 aa)
RPS16ribosomal protein S16 (146 aa)
MRPS9mitochondrial ribosomal protein S9 (396 aa)
HACE1HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 (909 aa)
RPS27Aribosomal protein S27a (156 aa)
PSMD2proteasome (prosome, macropain) 26S subunit, non-ATPase, 2; Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins (908 aa)
PLECplectin (4684 aa)
RPS7ribosomal protein S7; Required for rRNA maturation (194 aa)
UBE4Bubiquitination factor E4B; Binds to the ubiquitin moieties of preformed conjugates and catalyzes ubiquitin chain assembly in conjunction with E1, E2, and E3 (By similarity) (1302 aa)
RPS17ribosomal protein S17 (135 aa)
RPS17Lribosomal protein S17-like (135 aa)
RAD23BRAD23 homolog B (S. cerevisiae); Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Binds to polyubiquitin chains. Proposed to be capable to bind simultaneously to the 26S proteasome and to polyubiquitinated substrates and to deliver ubiquitinated proteins to the proteasome. May play a role in endoplasmic reticulum- associated degradation (ERAD) of misfolded glycoproteins by association with PNGase and delivering deglycosylated proteins to the proteasome (409 aa)
PSMD4proteasome (prosome, macropain) 26S subunit, non-ATPase, 4; Binds and presumably selects ubiquitin-conjugates for destruction. Displays selectivity for longer polyubiquitin chains. Modulates intestinal fluid secretion (377 aa)
UBQLNLubiquilin-like (475 aa)
UBE4Aubiquitination factor E4A; Binds to the ubiquitin moieties of preformed conjugates and catalyzes ubiquitin chain assembly in conjunction with E1, E2, and E3 (By similarity) (1073 aa)
UBA52ubiquitin A-52 residue ribosomal protein fusion product 1 (128 aa)
RPS24ribosomal protein S24; Required for processing of pre-rRNA and maturation of 40S ribosomal subunits (289 aa)
FAUFinkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed (133 aa)
PUF60poly-U binding splicing factor 60KDa; DNA- and RNA-binding protein, involved in several nuclear processes such as pre-mRNA splicing, apoptosis and transcription regulation. In association with FUBP1 regulates MYC transcription at the P2 promoter through the core-TFIIH basal transcription factor. Acts as a transcriptional repressor through the core-TFIIH basal transcription factor. Represses FUBP1-induced transcriptional activation but not basal transcription. Decreases ERCC3 helicase activity. Does not repress TFIIH-mediated transcription in xeroderma pigmentosum complementation group [...] (559 aa)
RPS25ribosomal protein S25 (125 aa)
ENSG00000260836Uncharacterized protein (293 aa)
RAD23ARAD23 homolog A (S. cerevisiae); Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Binds to ’Lys-48’-linked polyubiquitin chains in a length-dependent manner and with a lower affinity to ’Lys-63’-linked polyubiquitin chains. Proposed to be capable to bind simultaneously to the 26S proteasome and to polyubiquitinated substrates and to deliver ubiquitinated proteins to the proteasome (363 aa)
RPS15ribosomal protein S15 (145 aa)
RPS19ribosomal protein S19; Required for pre-rRNA processing and maturation of 40S ribosomal subunits (145 aa)
RPS28ribosomal protein S28 (69 aa)
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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