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STRINGSTRING
SLC6A19 SLC6A19 SLC6A14 SLC6A14 SLC6A15 SLC6A15 SLC6A16 SLC6A16 TMEM27 TMEM27 SLC6A18 SLC6A18 SLC6A17 SLC6A17 SLC6A13 SLC6A13 SLC6A20 SLC6A20 SLC6A5 SLC6A5 RBM18 RBM18
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
SLC6A15solute carrier family 6 (neutral amino acid transporter), member 15; Functions as a sodium-dependent neutral amino acid transporter. Exhibits preference for the branched-chain amino acids, particularly leucine, valine and isoleucine and methionine. Mediates the saturable, pH-sensitive and electrogenic cotransport of proline and sodium ions with a stoichiometry of 1-1. May have a role as transporter for neurotransmitter precursors into neurons. In contrast to other members of the neurotransmitter transporter family, does not appear to be chloride-dependent (730 aa)
SLC6A19solute carrier family 6 (neutral amino acid transporter), member 19; Transporter that mediates epithelial resorption of neutral amino acids across the apical membrane of epithelial cells in the kidney and intestine. It appears that leucine is the preferred substrate, but all large neutral non-aromatic L-amino acids bind to this transporter. Uptake of leucine is sodium- dependent. In contrast to other members of the neurotransmitter transporter family, does not appear to be chloride-dependent (By similarity) (634 aa)
SLC6A18solute carrier family 6, member 18; Functions as a sodium and chloride-dependent neutral amino acid transporter (By similarity) (628 aa)
SLC6A17solute carrier family 6, member 17; Functions as a sodium-dependent vesicular transporter selective for proline, glycine, leucine and alanine. In contrast to other members of this neurotransmitter transporter family, does not appear to be chloride-dependent (By similarity) (727 aa)
SLC6A16solute carrier family 6, member 16 (736 aa)
SLC6A13solute carrier family 6 (neurotransmitter transporter, GABA), member 13; Sodium-dependent GABA and taurine transporter. In presynaptic terminals, regulates GABA signaling termination through GABA uptake. May also be involved in beta-alanine transport (602 aa)
SLC6A20solute carrier family 6 (proline IMINO transporter), member 20; Mediates the calcium-dependent uptake of imino acids such as L-proline, N-methyl-L-proline and pipecolate as well as N- methylated amino acids. Involved in the transport of glycine (592 aa)
SLC6A14solute carrier family 6 (amino acid transporter), member 14; Mediates the uptake of a broad range of neutral and cationic amino acids (with the exception of proline) in a Na(+)/Cl(-)-dependent manner (642 aa)
TMEM27transmembrane protein 27; Regulator of SNARE complex function. Stimulator of beta cell replication (222 aa)
RBM18RNA binding motif protein 18 (190 aa)
SLC6A5solute carrier family 6 (neurotransmitter transporter, glycine), member 5; Terminates the action of glycine by its high affinity sodium-dependent reuptake into presynaptic terminals. May be responsible for the termination of neurotransmission at strychnine-sensitive glycinergic synapses (797 aa)
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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