node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AP1G1 | GGA1 | ENSP00000377148 | ENSP00000341344 | adaptor-related protein complex 1, gamma 1 subunit; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules | golgi-associated, gamma adaptin ear containing, ARF binding protein 1 | 0.502 |
AP1G1 | GGA2 | ENSP00000377148 | ENSP00000311962 | adaptor-related protein complex 1, gamma 1 subunit; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules | golgi-associated, gamma adaptin ear containing, ARF binding protein 2; Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates the ARF- dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (AC-LL) motif | 0.504 |
AP1G1 | SYNRG | ENSP00000377148 | ENSP00000343610 | adaptor-related protein complex 1, gamma 1 subunit; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules | synergin, gamma; May play a role in endocytosis and/or membrane trafficking at the trans-Golgi network (TGN). May act by linking the adapter protein complex AP-1 to other proteins | 0.990 |
AP1G1 | UBC | ENSP00000377148 | ENSP00000344818 | adaptor-related protein complex 1, gamma 1 subunit; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules | ubiquitin C | 0.747 |
CCDC91 | GGA1 | ENSP00000370658 | ENSP00000341344 | coiled-coil domain containing 91; Involved in the regulation of membrane traffic through the trans-Golgi network (TGN) | golgi-associated, gamma adaptin ear containing, ARF binding protein 1 | 0.923 |
CCDC91 | GGA2 | ENSP00000370658 | ENSP00000311962 | coiled-coil domain containing 91; Involved in the regulation of membrane traffic through the trans-Golgi network (TGN) | golgi-associated, gamma adaptin ear containing, ARF binding protein 2; Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates the ARF- dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (AC-LL) motif | 0.576 |
CCDC91 | SYNRG | ENSP00000370658 | ENSP00000343610 | coiled-coil domain containing 91; Involved in the regulation of membrane traffic through the trans-Golgi network (TGN) | synergin, gamma; May play a role in endocytosis and/or membrane trafficking at the trans-Golgi network (TGN). May act by linking the adapter protein complex AP-1 to other proteins | 0.576 |
CCDC91 | UBC | ENSP00000370658 | ENSP00000344818 | coiled-coil domain containing 91; Involved in the regulation of membrane traffic through the trans-Golgi network (TGN) | ubiquitin C | 0.483 |
EWSR1 | UBC | ENSP00000400142 | ENSP00000344818 | Ewing sarcoma breakpoint region 1; Might normally function as a transcriptionnal repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes | ubiquitin C | 0.929 |
GGA1 | AP1G1 | ENSP00000341344 | ENSP00000377148 | golgi-associated, gamma adaptin ear containing, ARF binding protein 1 | adaptor-related protein complex 1, gamma 1 subunit; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules | 0.502 |
GGA1 | CCDC91 | ENSP00000341344 | ENSP00000370658 | golgi-associated, gamma adaptin ear containing, ARF binding protein 1 | coiled-coil domain containing 91; Involved in the regulation of membrane traffic through the trans-Golgi network (TGN) | 0.923 |
GGA1 | GGA2 | ENSP00000341344 | ENSP00000311962 | golgi-associated, gamma adaptin ear containing, ARF binding protein 1 | golgi-associated, gamma adaptin ear containing, ARF binding protein 2; Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates the ARF- dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (AC-LL) motif | 0.736 |
GGA1 | SYNRG | ENSP00000341344 | ENSP00000343610 | golgi-associated, gamma adaptin ear containing, ARF binding protein 1 | synergin, gamma; May play a role in endocytosis and/or membrane trafficking at the trans-Golgi network (TGN). May act by linking the adapter protein complex AP-1 to other proteins | 0.989 |
GGA1 | UBC | ENSP00000341344 | ENSP00000344818 | golgi-associated, gamma adaptin ear containing, ARF binding protein 1 | ubiquitin C | 0.997 |
GGA2 | AP1G1 | ENSP00000311962 | ENSP00000377148 | golgi-associated, gamma adaptin ear containing, ARF binding protein 2; Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates the ARF- dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (AC-LL) motif | adaptor-related protein complex 1, gamma 1 subunit; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules | 0.504 |
GGA2 | CCDC91 | ENSP00000311962 | ENSP00000370658 | golgi-associated, gamma adaptin ear containing, ARF binding protein 2; Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates the ARF- dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (AC-LL) motif | coiled-coil domain containing 91; Involved in the regulation of membrane traffic through the trans-Golgi network (TGN) | 0.576 |
GGA2 | GGA1 | ENSP00000311962 | ENSP00000341344 | golgi-associated, gamma adaptin ear containing, ARF binding protein 2; Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates the ARF- dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (AC-LL) motif | golgi-associated, gamma adaptin ear containing, ARF binding protein 1 | 0.736 |
GGA2 | SYNRG | ENSP00000311962 | ENSP00000343610 | golgi-associated, gamma adaptin ear containing, ARF binding protein 2; Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates the ARF- dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (AC-LL) motif | synergin, gamma; May play a role in endocytosis and/or membrane trafficking at the trans-Golgi network (TGN). May act by linking the adapter protein complex AP-1 to other proteins | 0.920 |
GGA2 | UBC | ENSP00000311962 | ENSP00000344818 | golgi-associated, gamma adaptin ear containing, ARF binding protein 2; Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates the ARF- dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (AC-LL) motif | ubiquitin C | 0.804 |
SYNRG | AP1G1 | ENSP00000343610 | ENSP00000377148 | synergin, gamma; May play a role in endocytosis and/or membrane trafficking at the trans-Golgi network (TGN). May act by linking the adapter protein complex AP-1 to other proteins | adaptor-related protein complex 1, gamma 1 subunit; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules | 0.990 |