26 items (Homo sapiens) - STRING network view

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Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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protein of unknown 3D structure

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Your Input:
	MRPL27	mitochondrial ribosomal protein L27 (148 aa)
	MRPL51	mitochondrial ribosomal protein L51 (128 aa)
	MRPL4	mitochondrial ribosomal protein L4 (311 aa)
	MRPS25	mitochondrial ribosomal protein S25 (173 aa)
	PTCD3	pentatricopeptide repeat domain 3; Mitochondrial RNA-binding protein that has a role in mitochondrial translation (689 aa)
	MRPS27	mitochondrial ribosomal protein S27 (414 aa)
	MTIF2	mitochondrial translational initiation factor 2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (727 aa)
	MRPL3	mitochondrial ribosomal protein L3 (348 aa)
	MRPL49	mitochondrial ribosomal protein L49 (166 aa)
	GFM2	G elongation factor, mitochondrial 2; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation (779 aa)
	ICT1	immature colon carcinoma transcript 1; Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes (206 aa)
	MRPL39	mitochondrial ribosomal protein L39 (353 aa)
	MRPL13	mitochondrial ribosomal protein L13 (178 aa)
	MRPL38	mitochondrial ribosomal protein L38 (380 aa)
	MRPL1	mitochondrial ribosomal protein L1 (325 aa)
	MRPS31	mitochondrial ribosomal protein S31 (395 aa)
	MRPS33	mitochondrial ribosomal protein S33 (106 aa)
	MRPL54	mitochondrial ribosomal protein L54 (138 aa)
	DAP3	death associated protein 3; Involved in mediating interferon-gamma-induced cell death (398 aa)
	MRPL52	mitochondrial ribosomal protein L52 (123 aa)
	MRPL41	mitochondrial ribosomal protein L41; Component of the mitochondrial ribosome large subunit. Also involved in apoptosis and cell cycle. Enhances p53/TP53 stability, thereby contributing to p53/TP53-induced apoptosis in response to growth-inhibitory condition. Enhances p53/TP53 translocation to the mitochondria. Has the ability to arrest the cell cycle at the G1 phase, possibly by stabilizing the CDKN1A and CDKN1B (p27Kip1) proteins (137 aa)
	MRPS15	mitochondrial ribosomal protein S15 (257 aa)
	MRPL23	mitochondrial ribosomal protein L23 (153 aa)
	MRPL47	mitochondrial ribosomal protein L47 (250 aa)
	MRPS30	mitochondrial ribosomal protein S30 (439 aa)
	MRPL42	mitochondrial ribosomal protein L42 (142 aa)

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DAP3	ICT1	ENSP00000341692	ENSP00000301585	death associated protein 3; Involved in mediating interferon-gamma-induced cell death	immature colon carcinoma transcript 1; Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes	0.693
DAP3	MRPL23	ENSP00000341692	ENSP00000370930	death associated protein 3; Involved in mediating interferon-gamma-induced cell death	mitochondrial ribosomal protein L23	0.426
DAP3	MRPL4	ENSP00000341692	ENSP00000253099	death associated protein 3; Involved in mediating interferon-gamma-induced cell death	mitochondrial ribosomal protein L4	0.671
DAP3	MRPL42	ENSP00000341692	ENSP00000447547	death associated protein 3; Involved in mediating interferon-gamma-induced cell death	mitochondrial ribosomal protein L42	0.563
DAP3	MRPS15	ENSP00000341692	ENSP00000362208	death associated protein 3; Involved in mediating interferon-gamma-induced cell death	mitochondrial ribosomal protein S15	0.909
DAP3	MRPS27	ENSP00000341692	ENSP00000261413	death associated protein 3; Involved in mediating interferon-gamma-induced cell death	mitochondrial ribosomal protein S27	0.900
DAP3	MRPS30	ENSP00000341692	ENSP00000424328	death associated protein 3; Involved in mediating interferon-gamma-induced cell death	mitochondrial ribosomal protein S30	0.552
DAP3	PTCD3	ENSP00000341692	ENSP00000254630	death associated protein 3; Involved in mediating interferon-gamma-induced cell death	pentatricopeptide repeat domain 3; Mitochondrial RNA-binding protein that has a role in mitochondrial translation	0.641
GFM2	MRPL1	ENSP00000296805	ENSP00000315017	G elongation factor, mitochondrial 2; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation	mitochondrial ribosomal protein L1	0.926
GFM2	MRPL13	ENSP00000296805	ENSP00000306548	G elongation factor, mitochondrial 2; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation	mitochondrial ribosomal protein L13	0.931
GFM2	MRPL27	ENSP00000296805	ENSP00000225969	G elongation factor, mitochondrial 2; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation	mitochondrial ribosomal protein L27	0.712
GFM2	MRPL3	ENSP00000296805	ENSP00000264995	G elongation factor, mitochondrial 2; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation	mitochondrial ribosomal protein L3	0.974
GFM2	MRPL39	ENSP00000296805	ENSP00000305682	G elongation factor, mitochondrial 2; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation	mitochondrial ribosomal protein L39	0.500
GFM2	MRPL4	ENSP00000296805	ENSP00000253099	G elongation factor, mitochondrial 2; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation	mitochondrial ribosomal protein L4	0.974
GFM2	MRPS15	ENSP00000296805	ENSP00000362208	G elongation factor, mitochondrial 2; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation	mitochondrial ribosomal protein S15	0.663
GFM2	MTIF2	ENSP00000296805	ENSP00000263629	G elongation factor, mitochondrial 2; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation	mitochondrial translational initiation factor 2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	0.721
ICT1	DAP3	ENSP00000301585	ENSP00000341692	immature colon carcinoma transcript 1; Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes	death associated protein 3; Involved in mediating interferon-gamma-induced cell death	0.693
ICT1	MRPL1	ENSP00000301585	ENSP00000315017	immature colon carcinoma transcript 1; Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes	mitochondrial ribosomal protein L1	0.453
ICT1	MRPL13	ENSP00000301585	ENSP00000306548	immature colon carcinoma transcript 1; Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes	mitochondrial ribosomal protein L13	0.903
ICT1	MRPL23	ENSP00000301585	ENSP00000370930	immature colon carcinoma transcript 1; Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes	mitochondrial ribosomal protein L23	0.951

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