node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
HNF1B | ONECUT1 | ENSP00000225893 | ENSP00000302630 | HNF1 homeobox B; Transcription factor, probably binds to the inverted palindrome 5’-GTTAATNATTAAC-3’ | one cut homeobox 1; Transcriptional activator. Binds the consensus sequence 5’-DHWATTGAYTWWD-3’ on a variety of gene promoters such as those of HNF3B and TTR. Important for liver genes transcription | 0.973 |
HNF1B | ONECUT3 | ENSP00000225893 | ENSP00000371786 | HNF1 homeobox B; Transcription factor, probably binds to the inverted palindrome 5’-GTTAATNATTAAC-3’ | one cut homeobox 3; Transcriptional activator. Binds the consensus DNA sequence 5’-DHWATTGAYTWWD-3’ on a variety of gene promoters such as those of HNF3B and TTR (By similarity) | 0.929 |
NR3C1 | ONECUT1 | ENSP00000231509 | ENSP00000302630 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor); Receptor for glucocorticoids (GC). Has a dual mode of action- as a transcription factor that binds to glucocorticoid response elements (GRE), both for nuclear and mitochondrial DNA, and as a modulator of other transcription factors. Affects inflammatory responses, cellular proliferation and differentiation in target tissues. Could act as a coactivator for STAT5-dependent transcription upon growth hormone (GH) stimulation and could reveal an essential role of hepatic GR in the control of body growth. Involved in [...] | one cut homeobox 1; Transcriptional activator. Binds the consensus sequence 5’-DHWATTGAYTWWD-3’ on a variety of gene promoters such as those of HNF3B and TTR. Important for liver genes transcription | 0.603 |
NR3C1 | PRDM10 | ENSP00000231509 | ENSP00000351686 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor); Receptor for glucocorticoids (GC). Has a dual mode of action- as a transcription factor that binds to glucocorticoid response elements (GRE), both for nuclear and mitochondrial DNA, and as a modulator of other transcription factors. Affects inflammatory responses, cellular proliferation and differentiation in target tissues. Could act as a coactivator for STAT5-dependent transcription upon growth hormone (GH) stimulation and could reveal an essential role of hepatic GR in the control of body growth. Involved in [...] | PR domain containing 10 | 0.578 |
NR3C1 | SARM1 | ENSP00000231509 | ENSP00000406738 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor); Receptor for glucocorticoids (GC). Has a dual mode of action- as a transcription factor that binds to glucocorticoid response elements (GRE), both for nuclear and mitochondrial DNA, and as a modulator of other transcription factors. Affects inflammatory responses, cellular proliferation and differentiation in target tissues. Could act as a coactivator for STAT5-dependent transcription upon growth hormone (GH) stimulation and could reveal an essential role of hepatic GR in the control of body growth. Involved in [...] | sterile alpha and TIR motif containing 1 | 0.672 |
ONECUT1 | HNF1B | ENSP00000302630 | ENSP00000225893 | one cut homeobox 1; Transcriptional activator. Binds the consensus sequence 5’-DHWATTGAYTWWD-3’ on a variety of gene promoters such as those of HNF3B and TTR. Important for liver genes transcription | HNF1 homeobox B; Transcription factor, probably binds to the inverted palindrome 5’-GTTAATNATTAAC-3’ | 0.973 |
ONECUT1 | NR3C1 | ENSP00000302630 | ENSP00000231509 | one cut homeobox 1; Transcriptional activator. Binds the consensus sequence 5’-DHWATTGAYTWWD-3’ on a variety of gene promoters such as those of HNF3B and TTR. Important for liver genes transcription | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor); Receptor for glucocorticoids (GC). Has a dual mode of action- as a transcription factor that binds to glucocorticoid response elements (GRE), both for nuclear and mitochondrial DNA, and as a modulator of other transcription factors. Affects inflammatory responses, cellular proliferation and differentiation in target tissues. Could act as a coactivator for STAT5-dependent transcription upon growth hormone (GH) stimulation and could reveal an essential role of hepatic GR in the control of body growth. Involved in [...] | 0.603 |
ONECUT1 | ONECUT3 | ENSP00000302630 | ENSP00000371786 | one cut homeobox 1; Transcriptional activator. Binds the consensus sequence 5’-DHWATTGAYTWWD-3’ on a variety of gene promoters such as those of HNF3B and TTR. Important for liver genes transcription | one cut homeobox 3; Transcriptional activator. Binds the consensus DNA sequence 5’-DHWATTGAYTWWD-3’ on a variety of gene promoters such as those of HNF3B and TTR (By similarity) | 0.907 |
ONECUT3 | HNF1B | ENSP00000371786 | ENSP00000225893 | one cut homeobox 3; Transcriptional activator. Binds the consensus DNA sequence 5’-DHWATTGAYTWWD-3’ on a variety of gene promoters such as those of HNF3B and TTR (By similarity) | HNF1 homeobox B; Transcription factor, probably binds to the inverted palindrome 5’-GTTAATNATTAAC-3’ | 0.929 |
ONECUT3 | ONECUT1 | ENSP00000371786 | ENSP00000302630 | one cut homeobox 3; Transcriptional activator. Binds the consensus DNA sequence 5’-DHWATTGAYTWWD-3’ on a variety of gene promoters such as those of HNF3B and TTR (By similarity) | one cut homeobox 1; Transcriptional activator. Binds the consensus sequence 5’-DHWATTGAYTWWD-3’ on a variety of gene promoters such as those of HNF3B and TTR. Important for liver genes transcription | 0.907 |
PRDM10 | NR3C1 | ENSP00000351686 | ENSP00000231509 | PR domain containing 10 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor); Receptor for glucocorticoids (GC). Has a dual mode of action- as a transcription factor that binds to glucocorticoid response elements (GRE), both for nuclear and mitochondrial DNA, and as a modulator of other transcription factors. Affects inflammatory responses, cellular proliferation and differentiation in target tissues. Could act as a coactivator for STAT5-dependent transcription upon growth hormone (GH) stimulation and could reveal an essential role of hepatic GR in the control of body growth. Involved in [...] | 0.578 |
SARM1 | NR3C1 | ENSP00000406738 | ENSP00000231509 | sterile alpha and TIR motif containing 1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor); Receptor for glucocorticoids (GC). Has a dual mode of action- as a transcription factor that binds to glucocorticoid response elements (GRE), both for nuclear and mitochondrial DNA, and as a modulator of other transcription factors. Affects inflammatory responses, cellular proliferation and differentiation in target tissues. Could act as a coactivator for STAT5-dependent transcription upon growth hormone (GH) stimulation and could reveal an essential role of hepatic GR in the control of body growth. Involved in [...] | 0.672 |