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MZF1 | myeloid zinc finger 1; Binds to target promoter DNA and functions as trancription regulator. Regulates transcription from the PADI1 and CDH2 promoter. May be one regulator of transcriptional events during hemopoietic development (734 aa) | |||
PHF16 | PHD finger protein 16; Component of the HBO1 complex which has a histone H4- specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo (823 aa) | |||
ZNF862 | zinc finger protein 862; May be involved in transcriptional regulation (By similarity) (1169 aa) | |||
PHF17 | PHD finger protein 17 (842 aa) | |||
ZNF317 | zinc finger protein 317; May function as a transcription factor. May play an important role in erythroid maturation and lymphoid proliferation (595 aa) | |||
ZNF337 | zinc finger protein 337; May be involved in transcriptional regulation (751 aa) | |||
ZNF331 | zinc finger protein 331; May be involved in transcriptional regulation. May play a role in spermatogenesis (463 aa) | |||
ZNF700 | zinc finger protein 700; May be involved in transcriptional regulation (742 aa) | |||
ZNF256 | zinc finger protein 256; Transcriptional repressor that plays a role in cell proliferation. Requires TRIM28 for its activity (627 aa) | |||
ZNF117 | zinc finger protein 117; May be involved in transcriptional regulation (483 aa) | |||
ZNF667 | zinc finger protein 667; May be involved in transcriptional regulation (By similarity) (610 aa) | |||
KLF14 | Kruppel-like factor 14 (323 aa) | |||
SAV1 | salvador homolog 1 (Drosophila); Regulator of STK3/MST2 and STK4/MST1 in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Phosphorylation of YAP1 by LATS1/2 inhibits its translocation into the n [...] (383 aa) | |||
ZNF789 | zinc finger protein 789; May be involved in transcriptional regulation (425 aa) | |||
ZNF677 | zinc finger protein 677; May be involved in transcriptional regulation (584 aa) | |||
ZNF664 | zinc finger protein 664; May be involved in transcriptional regulation (261 aa) | |||
PRDM8 | PR domain containing 8; May be involved in transcriptional regulation (689 aa) | |||
RBPMS | RNA binding protein with multiple splicing; Acts as a coactivator of transcriptional activity. Required to increase TGFB1/Smad-mediated transactivation. Acts through SMAD2, SMAD3 and SMAD4 to increase transcriptional activity. Increases phosphorylation of SMAD2 and SMAD3 on their C- terminal SSXS motif, possibly through recruitment of TGFBR1. Promotes the nuclear accumulation of SMAD2, SMAD3 and SMAD4 proteins. Binds to poly(A) RNA (219 aa) | |||
ZNF823 | zinc finger protein 823; May be involved in transcriptional regulation (610 aa) | |||
UBC | ubiquitin C (685 aa) | |||
SIN3A | SIN3 transcription regulator homolog A (yeast); Acts as a transcriptional repressor. Corepressor for REST. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Also interacts with MXD1-MAX heterodimers to repress transcription by tethering SIN3A to DNA (By similarity). Acts cooperatively with OGT to repress transcription in parallel with histone deacetylation (1273 aa) | |||
AGTPBP1 | ATP/GTP binding protein 1 (1186 aa) | |||
KIAA1217 | KIAA1217 (1943 aa) | |||
SIN3B | SIN3 transcription regulator homolog B (yeast); Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription (By similarity) (1162 aa) | |||
NYNRIN | NYN domain and retroviral integrase containing (1898 aa) | |||
PHF15 | PHD finger protein 15; Component of the HBO1 complex which has a histone H4- specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo (790 aa) |