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STRINGSTRING
ZNF789 ZNF789 ZNF664 ZNF664 ZNF256 ZNF256 ZNF117 ZNF117 SAV1 SAV1 NYNRIN NYNRIN MZF1 MZF1 ZNF667 ZNF667 SIN3B SIN3B KLF14 KLF14 SIN3A SIN3A PHF17 PHF17 UBC UBC ZNF677 ZNF677 PHF16 PHF16 ZNF823 ZNF823 KIAA1217 KIAA1217 ZNF337 ZNF337 AGTPBP1 AGTPBP1 ZNF700 ZNF700 ZNF862 ZNF862 PRDM8 PRDM8 ZNF317 ZNF317 ZNF331 ZNF331 RBPMS RBPMS PHF15 PHF15
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
MZF1myeloid zinc finger 1; Binds to target promoter DNA and functions as trancription regulator. Regulates transcription from the PADI1 and CDH2 promoter. May be one regulator of transcriptional events during hemopoietic development (734 aa)
PHF16PHD finger protein 16; Component of the HBO1 complex which has a histone H4- specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo (823 aa)
ZNF862zinc finger protein 862; May be involved in transcriptional regulation (By similarity) (1169 aa)
PHF17PHD finger protein 17 (842 aa)
ZNF317zinc finger protein 317; May function as a transcription factor. May play an important role in erythroid maturation and lymphoid proliferation (595 aa)
ZNF337zinc finger protein 337; May be involved in transcriptional regulation (751 aa)
ZNF331zinc finger protein 331; May be involved in transcriptional regulation. May play a role in spermatogenesis (463 aa)
ZNF700zinc finger protein 700; May be involved in transcriptional regulation (742 aa)
ZNF256zinc finger protein 256; Transcriptional repressor that plays a role in cell proliferation. Requires TRIM28 for its activity (627 aa)
ZNF117zinc finger protein 117; May be involved in transcriptional regulation (483 aa)
ZNF667zinc finger protein 667; May be involved in transcriptional regulation (By similarity) (610 aa)
KLF14Kruppel-like factor 14 (323 aa)
SAV1salvador homolog 1 (Drosophila); Regulator of STK3/MST2 and STK4/MST1 in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Phosphorylation of YAP1 by LATS1/2 inhibits its translocation into the n [...] (383 aa)
ZNF789zinc finger protein 789; May be involved in transcriptional regulation (425 aa)
ZNF677zinc finger protein 677; May be involved in transcriptional regulation (584 aa)
ZNF664zinc finger protein 664; May be involved in transcriptional regulation (261 aa)
PRDM8PR domain containing 8; May be involved in transcriptional regulation (689 aa)
RBPMSRNA binding protein with multiple splicing; Acts as a coactivator of transcriptional activity. Required to increase TGFB1/Smad-mediated transactivation. Acts through SMAD2, SMAD3 and SMAD4 to increase transcriptional activity. Increases phosphorylation of SMAD2 and SMAD3 on their C- terminal SSXS motif, possibly through recruitment of TGFBR1. Promotes the nuclear accumulation of SMAD2, SMAD3 and SMAD4 proteins. Binds to poly(A) RNA (219 aa)
ZNF823zinc finger protein 823; May be involved in transcriptional regulation (610 aa)
UBCubiquitin C (685 aa)
SIN3ASIN3 transcription regulator homolog A (yeast); Acts as a transcriptional repressor. Corepressor for REST. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Also interacts with MXD1-MAX heterodimers to repress transcription by tethering SIN3A to DNA (By similarity). Acts cooperatively with OGT to repress transcription in parallel with histone deacetylation (1273 aa)
AGTPBP1ATP/GTP binding protein 1 (1186 aa)
KIAA1217KIAA1217 (1943 aa)
SIN3BSIN3 transcription regulator homolog B (yeast); Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription (By similarity) (1162 aa)
NYNRINNYN domain and retroviral integrase containing (1898 aa)
PHF15PHD finger protein 15; Component of the HBO1 complex which has a histone H4- specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo (790 aa)
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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