26 items (Homo sapiens) - STRING network view

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	OSTM1	osteopetrosis associated transmembrane protein 1; Required for osteoclast and melanocyte maturation and function (By similarity) (334 aa)
	BIRC7	baculoviral IAP repeat containing 7; Apoptotic regulator capable of exerting proapoptotic and anti-apoptotic activities and plays crucial roles in apoptosis, cell proliferation, and cell cycle control. Its anti-apoptotic activity is mediated through the inhibition of CASP3, CASP7 and CASP9, as well as by its E3 ubiquitin-protein ligase activity. As it is a weak caspase inhibitor, its anti-apoptotic activity is thought to be due to its ability to ubiquitinate DIABLO/SMAC targeting it for degradation thereby promoting cell survival. May contribute to caspase inhibition, by blocking the a [...] (298 aa)
	AK7	adenylate kinase 7; Adenylate kinase involved in maintaining ciliary structure and function (By similarity). Has highest activity toward AMP, and weaker activity toward dAMP, CMP and dCMP (723 aa)
	FAM177A1	family with sequence similarity 177, member A1 (236 aa)
	CD96	CD96 molecule; May be involved in adhesive interactions of activated T and NK cells during the late phase of the immune response. Promotes NK cell-target adhesion by interacting with PVR present on target cells. May function at a time after T and NK cells have penetrated the endothelium using integrins and selectins, when they are actively engaging diseased cells and moving within areas of inflammation (585 aa)
	PRSS12	protease, serine, 12 (neurotrypsin, motopsin); Plays a role in neuronal plasticity and the proteolytic action may subserve structural reorganizations associated with learning and memory operations (By similarity) (875 aa)
	AK8	adenylate kinase 8; Adenylate kinase. Has highest activity toward AMP, and weaker activity toward dAMP, CMP and dCMP (479 aa)
	MCOLN3	mucolipin 3 (553 aa)
	PACS1	phosphofurin acidic cluster sorting protein 1 (963 aa)
	FAM46A	family with sequence similarity 46, member A (442 aa)
	AK4	adenylate kinase 4; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor (223 aa)
	PRSS57	protease, serine, 57 (283 aa)
	RNF13	ring finger protein 13; E3 ubiquitin-protein ligase that may play a role in controlling cell proliferation (381 aa)
	XRCC3	X-ray repair complementing defective repair in Chinese hamster cells 3; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions. Plays a role in regulating mitochondrial DNA copy number under conditions of oxidative stress in the presence of RAD51 and RAD51C (346 aa)
	RAB5C	RAB5C, member RAS oncogene family; Protein transport. Probably involved in vesicular traffic (By similarity) (216 aa)
	AK5	adenylate kinase 5; Active on AMP and dAMP with ATP as a donor. When GTP is used as phosphate donor, the enzyme phosphorylates AMP, CMP, and to a small extent dCMP (562 aa)
	AK2	adenylate kinase 2 (239 aa)
	SLC33A1	solute carrier family 33 (acetyl-CoA transporter), member 1; Probable acetyl-CoA transporter necessary for O- acetylation of gangliosides (549 aa)
	TMEM9	transmembrane protein 9; May be involved in intracellular transport (183 aa)
	CMPK1	cytidine monophosphate (UMP-CMP) kinase 1, cytosolic; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors (228 aa)
	AK1	adenylate kinase 1; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (194 aa)
	AK3	adenylate kinase 3; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP-AMP phosphotransferase and ITP-AMP phosphotransferase activities (227 aa)
	CLCN7	chloride channel, voltage-sensitive 7; Slowly voltage-gated channel mediating the exchange of chloride ions against protons. Functions as antiporter and contributes to the acidification of the lysosome lumen (805 aa)
	LAMP2	lysosomal-associated membrane protein 2; Implicated in tumor cell metastasis. May function in protection of the lysosomal membrane from autodigestion, maintenance of the acidic environment of the lysosome, adhesion when expressed on the cell surface (plasma membrane), and inter- and intracellular signal transduction. Protects cells from the toxic effects of methylating mutagens (411 aa)
	AKD1	adenylate kinase domain containing 1 (1911 aa)
	TMEM9B	TMEM9 domain family, member B (198 aa)

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AK1	AK7	ENSP00000362249	ENSP00000267584	adenylate kinase 1; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adenylate kinase 7; Adenylate kinase involved in maintaining ciliary structure and function (By similarity). Has highest activity toward AMP, and weaker activity toward dAMP, CMP and dCMP	0.734
AK2	CMPK1	ENSP00000346921	ENSP00000360939	adenylate kinase 2	cytidine monophosphate (UMP-CMP) kinase 1, cytosolic; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors	0.520
AK3	AK5	ENSP00000371230	ENSP00000346577	adenylate kinase 3; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP-AMP phosphotransferase and ITP-AMP phosphotransferase activities	adenylate kinase 5; Active on AMP and dAMP with ATP as a donor. When GTP is used as phosphate donor, the enzyme phosphorylates AMP, CMP, and to a small extent dCMP	0.445
AK3	CMPK1	ENSP00000371230	ENSP00000360939	adenylate kinase 3; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP-AMP phosphotransferase and ITP-AMP phosphotransferase activities	cytidine monophosphate (UMP-CMP) kinase 1, cytosolic; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors	0.939
AK4	AK7	ENSP00000322175	ENSP00000267584	adenylate kinase 4; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor	adenylate kinase 7; Adenylate kinase involved in maintaining ciliary structure and function (By similarity). Has highest activity toward AMP, and weaker activity toward dAMP, CMP and dCMP	0.545
AK5	AK3	ENSP00000346577	ENSP00000371230	adenylate kinase 5; Active on AMP and dAMP with ATP as a donor. When GTP is used as phosphate donor, the enzyme phosphorylates AMP, CMP, and to a small extent dCMP	adenylate kinase 3; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP-AMP phosphotransferase and ITP-AMP phosphotransferase activities	0.445
AK5	AK7	ENSP00000346577	ENSP00000267584	adenylate kinase 5; Active on AMP and dAMP with ATP as a donor. When GTP is used as phosphate donor, the enzyme phosphorylates AMP, CMP, and to a small extent dCMP	adenylate kinase 7; Adenylate kinase involved in maintaining ciliary structure and function (By similarity). Has highest activity toward AMP, and weaker activity toward dAMP, CMP and dCMP	0.770
AK5	AK8	ENSP00000346577	ENSP00000298545	adenylate kinase 5; Active on AMP and dAMP with ATP as a donor. When GTP is used as phosphate donor, the enzyme phosphorylates AMP, CMP, and to a small extent dCMP	adenylate kinase 8; Adenylate kinase. Has highest activity toward AMP, and weaker activity toward dAMP, CMP and dCMP	0.459
AK7	AK1	ENSP00000267584	ENSP00000362249	adenylate kinase 7; Adenylate kinase involved in maintaining ciliary structure and function (By similarity). Has highest activity toward AMP, and weaker activity toward dAMP, CMP and dCMP	adenylate kinase 1; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	0.734
AK7	AK4	ENSP00000267584	ENSP00000322175	adenylate kinase 7; Adenylate kinase involved in maintaining ciliary structure and function (By similarity). Has highest activity toward AMP, and weaker activity toward dAMP, CMP and dCMP	adenylate kinase 4; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor	0.545
AK7	AK5	ENSP00000267584	ENSP00000346577	adenylate kinase 7; Adenylate kinase involved in maintaining ciliary structure and function (By similarity). Has highest activity toward AMP, and weaker activity toward dAMP, CMP and dCMP	adenylate kinase 5; Active on AMP and dAMP with ATP as a donor. When GTP is used as phosphate donor, the enzyme phosphorylates AMP, CMP, and to a small extent dCMP	0.770
AK7	AK8	ENSP00000267584	ENSP00000298545	adenylate kinase 7; Adenylate kinase involved in maintaining ciliary structure and function (By similarity). Has highest activity toward AMP, and weaker activity toward dAMP, CMP and dCMP	adenylate kinase 8; Adenylate kinase. Has highest activity toward AMP, and weaker activity toward dAMP, CMP and dCMP	0.632
AK7	AKD1	ENSP00000267584	ENSP00000410186	adenylate kinase 7; Adenylate kinase involved in maintaining ciliary structure and function (By similarity). Has highest activity toward AMP, and weaker activity toward dAMP, CMP and dCMP	adenylate kinase domain containing 1	0.801
AK7	CMPK1	ENSP00000267584	ENSP00000360939	adenylate kinase 7; Adenylate kinase involved in maintaining ciliary structure and function (By similarity). Has highest activity toward AMP, and weaker activity toward dAMP, CMP and dCMP	cytidine monophosphate (UMP-CMP) kinase 1, cytosolic; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors	0.517
AK8	AK5	ENSP00000298545	ENSP00000346577	adenylate kinase 8; Adenylate kinase. Has highest activity toward AMP, and weaker activity toward dAMP, CMP and dCMP	adenylate kinase 5; Active on AMP and dAMP with ATP as a donor. When GTP is used as phosphate donor, the enzyme phosphorylates AMP, CMP, and to a small extent dCMP	0.459
AK8	AK7	ENSP00000298545	ENSP00000267584	adenylate kinase 8; Adenylate kinase. Has highest activity toward AMP, and weaker activity toward dAMP, CMP and dCMP	adenylate kinase 7; Adenylate kinase involved in maintaining ciliary structure and function (By similarity). Has highest activity toward AMP, and weaker activity toward dAMP, CMP and dCMP	0.632
AK8	CMPK1	ENSP00000298545	ENSP00000360939	adenylate kinase 8; Adenylate kinase. Has highest activity toward AMP, and weaker activity toward dAMP, CMP and dCMP	cytidine monophosphate (UMP-CMP) kinase 1, cytosolic; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors	0.749
AKD1	AK7	ENSP00000410186	ENSP00000267584	adenylate kinase domain containing 1	adenylate kinase 7; Adenylate kinase involved in maintaining ciliary structure and function (By similarity). Has highest activity toward AMP, and weaker activity toward dAMP, CMP and dCMP	0.801
CLCN7	LAMP2	ENSP00000372193	ENSP00000408411	chloride channel, voltage-sensitive 7; Slowly voltage-gated channel mediating the exchange of chloride ions against protons. Functions as antiporter and contributes to the acidification of the lysosome lumen	lysosomal-associated membrane protein 2; Implicated in tumor cell metastasis. May function in protection of the lysosomal membrane from autodigestion, maintenance of the acidic environment of the lysosome, adhesion when expressed on the cell surface (plasma membrane), and inter- and intracellular signal transduction. Protects cells from the toxic effects of methylating mutagens	0.612
CLCN7	OSTM1	ENSP00000372193	ENSP00000193322	chloride channel, voltage-sensitive 7; Slowly voltage-gated channel mediating the exchange of chloride ions against protons. Functions as antiporter and contributes to the acidification of the lysosome lumen	osteopetrosis associated transmembrane protein 1; Required for osteoclast and melanocyte maturation and function (By similarity)	0.998

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