8 items (Homo sapiens) - STRING network view

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Size

small nodes:
protein of unknown 3D structure

large nodes:
some 3D structure is known or predicted

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HAL	histidine ammonia-lyase (657 aa)
	HDC	histidine decarboxylase; Catalyzes the biosynthesis of histamine from histidine (662 aa)
	CNDP2	CNDP dipeptidase 2 (metallopeptidase M20 family); Hydrolyzes a variety of dipeptides including L-carnosine but has a strong preference for Cys-Gly. Isoform 2 may be play a role as tumor suppressor in hepatocellular carcinoma (HCC) cells (475 aa)
	UBC	ubiquitin C (685 aa)
	DDC	dopa decarboxylase (aromatic L-amino acid decarboxylase); Catalyzes the decarboxylation of L-3,4- dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine (480 aa)
	CNDP1	carnosine dipeptidase 1 (metallopeptidase M20 family) (507 aa)
	METTL6	methyltransferase like 6; Probable methyltransferase (By similarity) (284 aa)
	CARNS1	carnosine synthase 1; Catalyzes the synthesis of carnosine and homocarnosine. Carnosine is synthesized more efficiently than homocarnosine (950 aa)

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but resolution at 400 dpi

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as simple tabular text output:

download

TSV: tab separated values - can be opened in Excel

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CARNS1	CNDP1	ENSP00000389009	ENSP00000351682	carnosine synthase 1; Catalyzes the synthesis of carnosine and homocarnosine. Carnosine is synthesized more efficiently than homocarnosine	carnosine dipeptidase 1 (metallopeptidase M20 family)	0.965
CARNS1	CNDP2	ENSP00000389009	ENSP00000325548	carnosine synthase 1; Catalyzes the synthesis of carnosine and homocarnosine. Carnosine is synthesized more efficiently than homocarnosine	CNDP dipeptidase 2 (metallopeptidase M20 family); Hydrolyzes a variety of dipeptides including L-carnosine but has a strong preference for Cys-Gly. Isoform 2 may be play a role as tumor suppressor in hepatocellular carcinoma (HCC) cells	0.942
CARNS1	DDC	ENSP00000389009	ENSP00000350616	carnosine synthase 1; Catalyzes the synthesis of carnosine and homocarnosine. Carnosine is synthesized more efficiently than homocarnosine	dopa decarboxylase (aromatic L-amino acid decarboxylase); Catalyzes the decarboxylation of L-3,4- dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine	0.903
CARNS1	HAL	ENSP00000389009	ENSP00000261208	carnosine synthase 1; Catalyzes the synthesis of carnosine and homocarnosine. Carnosine is synthesized more efficiently than homocarnosine	histidine ammonia-lyase	0.900
CARNS1	HDC	ENSP00000389009	ENSP00000267845	carnosine synthase 1; Catalyzes the synthesis of carnosine and homocarnosine. Carnosine is synthesized more efficiently than homocarnosine	histidine decarboxylase; Catalyzes the biosynthesis of histamine from histidine	0.903
CARNS1	METTL6	ENSP00000389009	ENSP00000373300	carnosine synthase 1; Catalyzes the synthesis of carnosine and homocarnosine. Carnosine is synthesized more efficiently than homocarnosine	methyltransferase like 6; Probable methyltransferase (By similarity)	0.900
CNDP1	CARNS1	ENSP00000351682	ENSP00000389009	carnosine dipeptidase 1 (metallopeptidase M20 family)	carnosine synthase 1; Catalyzes the synthesis of carnosine and homocarnosine. Carnosine is synthesized more efficiently than homocarnosine	0.965
CNDP1	CNDP2	ENSP00000351682	ENSP00000325548	carnosine dipeptidase 1 (metallopeptidase M20 family)	CNDP dipeptidase 2 (metallopeptidase M20 family); Hydrolyzes a variety of dipeptides including L-carnosine but has a strong preference for Cys-Gly. Isoform 2 may be play a role as tumor suppressor in hepatocellular carcinoma (HCC) cells	0.957
CNDP1	DDC	ENSP00000351682	ENSP00000350616	carnosine dipeptidase 1 (metallopeptidase M20 family)	dopa decarboxylase (aromatic L-amino acid decarboxylase); Catalyzes the decarboxylation of L-3,4- dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine	0.909
CNDP1	HAL	ENSP00000351682	ENSP00000261208	carnosine dipeptidase 1 (metallopeptidase M20 family)	histidine ammonia-lyase	0.900
CNDP1	HDC	ENSP00000351682	ENSP00000267845	carnosine dipeptidase 1 (metallopeptidase M20 family)	histidine decarboxylase; Catalyzes the biosynthesis of histamine from histidine	0.915
CNDP1	METTL6	ENSP00000351682	ENSP00000373300	carnosine dipeptidase 1 (metallopeptidase M20 family)	methyltransferase like 6; Probable methyltransferase (By similarity)	0.900
CNDP2	CARNS1	ENSP00000325548	ENSP00000389009	CNDP dipeptidase 2 (metallopeptidase M20 family); Hydrolyzes a variety of dipeptides including L-carnosine but has a strong preference for Cys-Gly. Isoform 2 may be play a role as tumor suppressor in hepatocellular carcinoma (HCC) cells	carnosine synthase 1; Catalyzes the synthesis of carnosine and homocarnosine. Carnosine is synthesized more efficiently than homocarnosine	0.942
CNDP2	CNDP1	ENSP00000325548	ENSP00000351682	CNDP dipeptidase 2 (metallopeptidase M20 family); Hydrolyzes a variety of dipeptides including L-carnosine but has a strong preference for Cys-Gly. Isoform 2 may be play a role as tumor suppressor in hepatocellular carcinoma (HCC) cells	carnosine dipeptidase 1 (metallopeptidase M20 family)	0.957
CNDP2	DDC	ENSP00000325548	ENSP00000350616	CNDP dipeptidase 2 (metallopeptidase M20 family); Hydrolyzes a variety of dipeptides including L-carnosine but has a strong preference for Cys-Gly. Isoform 2 may be play a role as tumor suppressor in hepatocellular carcinoma (HCC) cells	dopa decarboxylase (aromatic L-amino acid decarboxylase); Catalyzes the decarboxylation of L-3,4- dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine	0.909
CNDP2	HAL	ENSP00000325548	ENSP00000261208	CNDP dipeptidase 2 (metallopeptidase M20 family); Hydrolyzes a variety of dipeptides including L-carnosine but has a strong preference for Cys-Gly. Isoform 2 may be play a role as tumor suppressor in hepatocellular carcinoma (HCC) cells	histidine ammonia-lyase	0.901
CNDP2	HDC	ENSP00000325548	ENSP00000267845	CNDP dipeptidase 2 (metallopeptidase M20 family); Hydrolyzes a variety of dipeptides including L-carnosine but has a strong preference for Cys-Gly. Isoform 2 may be play a role as tumor suppressor in hepatocellular carcinoma (HCC) cells	histidine decarboxylase; Catalyzes the biosynthesis of histamine from histidine	0.919
CNDP2	METTL6	ENSP00000325548	ENSP00000373300	CNDP dipeptidase 2 (metallopeptidase M20 family); Hydrolyzes a variety of dipeptides including L-carnosine but has a strong preference for Cys-Gly. Isoform 2 may be play a role as tumor suppressor in hepatocellular carcinoma (HCC) cells	methyltransferase like 6; Probable methyltransferase (By similarity)	0.900
CNDP2	UBC	ENSP00000325548	ENSP00000344818	CNDP dipeptidase 2 (metallopeptidase M20 family); Hydrolyzes a variety of dipeptides including L-carnosine but has a strong preference for Cys-Gly. Isoform 2 may be play a role as tumor suppressor in hepatocellular carcinoma (HCC) cells	ubiquitin C	0.873
DDC	CARNS1	ENSP00000350616	ENSP00000389009	dopa decarboxylase (aromatic L-amino acid decarboxylase); Catalyzes the decarboxylation of L-3,4- dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine	carnosine synthase 1; Catalyzes the synthesis of carnosine and homocarnosine. Carnosine is synthesized more efficiently than homocarnosine	0.903

page 1 of 3

Experiments

Neighborhood

Databases

Cooccurrence

Textmining

Fusion

Coexpression

© STRING Consortium 2017

Credits

Access

Info

About