5 items (Homo sapiens) - STRING network view

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Size

small nodes:
protein of unknown 3D structure

large nodes:
some 3D structure is known or predicted

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RAB12	RAB12, member RAS oncogene family; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab may play a role in protein transport from recycling endosomes to lysosomes regulating, for instance, the degradation of the transferrin receptor (By similarity) (244 aa)
	UBC	ubiquitin C (685 aa)
	RAB13	RAB13, member RAS oncogene family; Could participate in polarized transport, in the assembly and/or the activity of tight junctions (203 aa)
	CCDC64B	coiled-coil domain containing 64B (508 aa)
	KLC3	kinesin light chain 3; Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport (504 aa)

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but resolution at 400 dpi

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as simple tabular text output:

download

TSV: tab separated values - can be opened in Excel

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCDC64B	KLC3	ENSP00000373998	ENSP00000375810	coiled-coil domain containing 64B	kinesin light chain 3; Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport	0.537
KLC3	CCDC64B	ENSP00000375810	ENSP00000373998	kinesin light chain 3; Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport	coiled-coil domain containing 64B	0.537
RAB12	UBC	ENSP00000331748	ENSP00000344818	RAB12, member RAS oncogene family; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab may play a role in protein transport from recycling endosomes to lysosomes regulating, for instance, the degradation of the transferrin receptor (By similarity)	ubiquitin C	0.777
RAB13	UBC	ENSP00000357564	ENSP00000344818	RAB13, member RAS oncogene family; Could participate in polarized transport, in the assembly and/or the activity of tight junctions	ubiquitin C	0.862
UBC	RAB12	ENSP00000344818	ENSP00000331748	ubiquitin C	RAB12, member RAS oncogene family; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab may play a role in protein transport from recycling endosomes to lysosomes regulating, for instance, the degradation of the transferrin receptor (By similarity)	0.777
UBC	RAB13	ENSP00000344818	ENSP00000357564	ubiquitin C	RAB13, member RAS oncogene family; Could participate in polarized transport, in the assembly and/or the activity of tight junctions	0.862

Experiments

Cooccurrence

Databases

Neighborhood

Textmining

Fusion

Coexpression

© STRING Consortium 2017

Credits

Access

Info

About