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STRINGSTRING
SLC25A17 SLC25A17 SLC22A6 SLC22A6 RPL27A RPL27A SLC22A8 SLC22A8 SLC22A25 SLC22A25 SLC22A1 SLC22A1 SVOP SVOP SLC22A10 SLC22A10 ESYT2 ESYT2 MOSPD3 MOSPD3 VAPA VAPA VAPB VAPB ESYT1 ESYT1 SLC22A11 SLC22A11 ESYT3 ESYT3 SLC22A2 SLC22A2 SLC22A7 SLC22A7 EXOC1 EXOC1 SLC22A9 SLC22A9 SLC22A23 SLC22A23 SV2B SV2B EXOC8 EXOC8 EXOC2 EXOC2 SLC22A24 SLC22A24 SLC22A12 SLC22A12 SV2C SV2C
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
MOSPD3motile sperm domain containing 3 (235 aa)
EXOC2exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane (924 aa)
ESYT2extended synaptotagmin-like protein 2 (893 aa)
ESYT1extended synaptotagmin-like protein 1; May play a role as calcium-regulated intrinsic membrane protein (By similarity) (1114 aa)
SLC22A9solute carrier family 22 (organic anion transporter), member 9 (553 aa)
SVOPSV2 related protein homolog (rat) (483 aa)
SLC22A11solute carrier family 22 (organic anion/urate transporter), member 11; Mediates saturable uptake of estrone sulfate, dehydroepiandrosterone sulfate and related compounds (550 aa)
SLC22A25solute carrier family 22, member 25 (547 aa)
EXOC1exocyst complex component 1; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane (894 aa)
SLC22A10solute carrier family 22, member 10 (541 aa)
SV2Bsynaptic vesicle glycoprotein 2B; Probably plays a role in the control of regulated secretion in neural and endocrine cells (By similarity) (683 aa)
SLC22A8solute carrier family 22 (organic anion transporter), member 8; Plays an important role in the excretion/detoxification of endogenous and exogenous organic anions, especially from the brain and kidney. Involved in the transport basolateral of steviol, fexofenadine. Transports benzylpenicillin (PCG), estrone- 3-sulfate (E1S), cimetidine (CMD), 2,4-dichloro-phenoxyacetate (2,4-D), p-amino-hippurate (PAH), acyclovir (ACV) and ochratoxin (OTA) (542 aa)
VAPAVAMP (vesicle-associated membrane protein)-associated protein A, 33kDa; May play a role in vesicle trafficking (294 aa)
RPL27Aribosomal protein L27a (148 aa)
EXOC8exocyst complex component 8; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane (725 aa)
SLC22A2solute carrier family 22 (organic cation transporter), member 2; Mediates tubular uptake of organic compounds from circulation. Mediates the influx of agmatine, dopamine, noradrenaline (norepinephrine), serotonin, choline, famotidine, ranitidine, histamin, creatinine, amantadine, memantine, acriflavine, 4-[4-(dimethylamino)-styryl]-N-methylpyridinium ASP, amiloride, metformin, N-1-methylnicotinamide (NMN), tetraethylammonium (TEA), 1-methyl-4-phenylpyridinium (MPP), cimetidine, cisplatin and oxaliplatin. Cisplatin may develop a nephrotoxic action. Transport of creatinine is inhibited b [...] (555 aa)
SLC22A1solute carrier family 22 (organic cation transporter), member 1; Translocates a broad array of organic cations with various structures and molecular weights including the model compounds 1-methyl-4-phenylpyridinium (MPP), tetraethylammonium (TEA), N-1-methylnicotinamide (NMN), 4-(4-(dimethylamino)styryl)- N-methylpyridinium (ASP), the endogenous compounds choline, guanidine, histamine, epinephrine, adrenaline, noradrenaline and dopamine, and the drugs quinine, and metformin. The transport of organic cations is inhibited by a broad array of compounds like tetramethylammonium (TMA), coca [...] (554 aa)
SLC22A7solute carrier family 22 (organic anion transporter), member 7; Mediates sodium-independent multispecific organic anion transport. Transport of prostaglandin E2, prostaglandin F2, tetracycline, bumetanide, estrone sulfate, glutarate, dehydroepiandrosterone sulfate, allopurinol, 5-fluorouracil, paclitaxel, L-ascorbic acid, salicylate, ethotrexate, and alpha- ketoglutarate (548 aa)
SLC22A12solute carrier family 22 (organic anion/urate transporter), member 12; Required for efficient urate re-absorption in the kidney. Regulates blood urate levels. Mediates saturable urate uptake by facilitating the exchange of urate against organic anions (553 aa)
SLC22A6solute carrier family 22 (organic anion transporter), member 6 (563 aa)
ESYT3extended synaptotagmin-like protein 3; May play a role as calcium-regulated intrinsic membrane protein (By similarity) (886 aa)
SLC22A23solute carrier family 22, member 23 (686 aa)
SLC25A17solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17; Peroxisomal transporter for multiple cofactors like coenzyme A (CoA), flavin adenine dinucleotide (FAD), flavin mononucleotide (FMN) and nucleotide adenosine monophosphate (AMP), and to a lesser extend for nicotinamide adenine dinucleotide (NAD(+)), adenosine diphosphate (ADP) and adenosine 3’,5’- diphosphate (PAP). May catalyze the transport of free CoA, FAD and NAD(+) from the cytosol into the peroxisomal matrix by a counter- exchange mechanism. Inhibited by pyridoxal 5’-phosphate and ba [...] (307 aa)
SLC22A24solute carrier family 22, member 24 (551 aa)
VAPBVAMP (vesicle-associated membrane protein)-associated protein B and C; Participates in the endoplasmic reticulum unfolded protein response (UPR) by inducing ERN1/IRE1 activity. Involved in cellular calcium homeostasis regulation (243 aa)
SV2Csynaptic vesicle glycoprotein 2C; Plays a role in the control of regulated secretion in neural and endocrine cells, enhancing selectively low-frequency neurotransmission. Positively regulates vesicle fusion by maintaining the readily releasable pool of secretory vesicles (By similarity) (727 aa)
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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